| MP term: | abnormal macrophage morphology |
| Synonym: | macrophage abnormalities |
| Synonym: | mononuclear phagocyte abnormalities |
| MP id: | MP:0002446 |
| Definition: | any structural anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells |
| Number of paths to term: | 7 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal myeloid leukocyte morphologyabnormal phagocyte morphologyabnormal mononuclear phagocyte morphologyabnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal monocyte morphology +abnormal myeloid dendritic cell morphology +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal professional antigen presenting cell morphologyabnormal dendritic cell morphology +abnormal macrophage morphology [MP:0002446] (593 genotypes, 734 annotations)abnormal alveolar macrophage morphologyabnormal Kupffer cell morphologyabnormal macrophage derived foam cell morphology +abnormal macrophage differentiationabnormal metallophilic macrophage morphologyabnormal microglial cell morphology +abnormal osteoclast morphology +abnormal peritoneal macrophage morphologyabnormal perivascular macrophage morphologyabnormal spleen marginal zone macrophage morphologydecreased macrophage cell number +increased macrophage cell number +abnormal mature B cell morphology +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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