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Mammalian Phenotype Browser
Term Detail
MP term:abnormal macrophage morphology
Synonym: macrophage abnormalities
Synonym: mononuclear phagocyte abnormalities
MP id: MP:0002446
Definition: any structural anomaly of the large mononuclear phagocytes which differentiate from monocytes, are typically resident in a particular tissue, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology [MP:0002446] (670 genotypes, 821 annotations)
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage cell number +
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology +
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +
                                                                is-aabnormal monocyte morphology +
                                                                is-aabnormal myeloid dendritic cell morphology +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal myeloid leukocyte morphology
                                                        is-aabnormal phagocyte morphology
                                                                is-aabnormal mononuclear phagocyte morphology
                                                                        is-aabnormal macrophage morphology [MP:0002446] (670 genotypes, 821 annotations)
                                                                                is-aabnormal alveolar macrophage morphology
                                                                                is-aabnormal Kupffer cell morphology
                                                                                is-aabnormal macrophage cell number +
                                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                                is-aabnormal macrophage differentiation
                                                                                is-aabnormal metallophilic macrophage morphology
                                                                                is-aabnormal microglial cell morphology +
                                                                                is-aabnormal osteoclast morphology +
                                                                                is-aabnormal peritoneal macrophage morphology
                                                                                is-aabnormal perivascular macrophage morphology
                                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                                is-adecreased macrophage cell number +
                                                                                is-aincreased macrophage cell number +
                                                                        is-aabnormal monocyte morphology +
                                                                        is-aabnormal myeloid dendritic cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal mononuclear phagocyte morphology
                                                        is-aabnormal macrophage morphology [MP:0002446] (670 genotypes, 821 annotations)
                                                                is-aabnormal alveolar macrophage morphology
                                                                is-aabnormal Kupffer cell morphology
                                                                is-aabnormal macrophage cell number +
                                                                is-aabnormal macrophage derived foam cell morphology +
                                                                is-aabnormal macrophage differentiation
                                                                is-aabnormal metallophilic macrophage morphology
                                                                is-aabnormal microglial cell morphology +
                                                                is-aabnormal osteoclast morphology +
                                                                is-aabnormal peritoneal macrophage morphology
                                                                is-aabnormal perivascular macrophage morphology
                                                                is-aabnormal spleen marginal zone macrophage morphology
                                                                is-adecreased macrophage cell number +
                                                                is-aincreased macrophage cell number +
                                                        is-aabnormal monocyte morphology +
                                                        is-aabnormal myeloid dendritic cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal myeloid leukocyte morphology
                                                is-aabnormal phagocyte morphology
                                                        is-aabnormal mononuclear phagocyte morphology
                                                                is-aabnormal macrophage morphology [MP:0002446] (670 genotypes, 821 annotations)
                                                                        is-aabnormal alveolar macrophage morphology
                                                                        is-aabnormal Kupffer cell morphology
                                                                        is-aabnormal macrophage cell number +
                                                                        is-aabnormal macrophage derived foam cell morphology +
                                                                        is-aabnormal macrophage differentiation
                                                                        is-aabnormal metallophilic macrophage morphology
                                                                        is-aabnormal microglial cell morphology +
                                                                        is-aabnormal osteoclast morphology +
                                                                        is-aabnormal peritoneal macrophage morphology
                                                                        is-aabnormal perivascular macrophage morphology
                                                                        is-aabnormal spleen marginal zone macrophage morphology
                                                                        is-adecreased macrophage cell number +
                                                                        is-aincreased macrophage cell number +
                                                                is-aabnormal monocyte morphology +
                                                                is-aabnormal myeloid dendritic cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal professional antigen presenting cell morphology
                                        is-aabnormal dendritic cell morphology +
                                        is-aabnormal macrophage morphology [MP:0002446] (670 genotypes, 821 annotations)
                                                is-aabnormal alveolar macrophage morphology
                                                is-aabnormal Kupffer cell morphology
                                                is-aabnormal macrophage cell number +
                                                is-aabnormal macrophage derived foam cell morphology +
                                                is-aabnormal macrophage differentiation
                                                is-aabnormal metallophilic macrophage morphology
                                                is-aabnormal microglial cell morphology +
                                                is-aabnormal osteoclast morphology +
                                                is-aabnormal peritoneal macrophage morphology
                                                is-aabnormal perivascular macrophage morphology
                                                is-aabnormal spleen marginal zone macrophage morphology
                                                is-adecreased macrophage cell number +
                                                is-aincreased macrophage cell number +
                                        is-aabnormal mature B cell morphology +

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory