| MP term: | abnormal B cell differentiation |
| Synonym: | abnormal B cell development |
| Synonym: | abnormal B-cell development |
| Synonym: | abnormal B cell maturation |
| Synonym: | abnormal B-cell maturation |
| Synonym: | abnormal B lymphocyte development |
| Synonym: | abnormal B lymphocyte maturation |
| Synonym: | abnormal lymphoid development/ B lymphocyte defects |
| Synonym: | B cell abnormalities |
| Synonym: | B-cell abnormalities |
| Synonym: | B lymphocyte abnormalities |
| Synonym: | immune system: lymphoid development/ B lymphocyte defects |
| MP id: | MP:0002144 |
| Alternate id: | MP:0001801, MP:0002438, MP:0001803 |
| Definition: | atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors |
| Number of paths to term: | 12 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal B cell number +abnormal immature B cell morphology +abnormal mature B cell morphology +abnormal plasma cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal B cell number +abnormal immature B cell morphology +abnormal mature B cell morphology +abnormal plasma cell morphology +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal bone marrow cell morphology/developmentabnormal myeloblast morphology/developmentabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal B cell number +abnormal immature B cell morphology +abnormal mature B cell morphology +abnormal plasma cell morphology +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiation [MP:0002144] (1032 genotypes, 1745 annotations)abnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiationabnormal NK cell differentiationabnormal T cell differentiation +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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