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Mammalian Phenotype Browser
Term Detail
MP term:abnormal B cell differentiation
Synonym: abnormal B cell development
Synonym: abnormal B-cell development
Synonym: abnormal B cell maturation
Synonym: abnormal B-cell maturation
Synonym: abnormal B lymphocyte development
Synonym: abnormal B lymphocyte maturation
Synonym: abnormal lymphoid development/ B lymphocyte defects
Synonym: B cell abnormalities
Synonym: B-cell abnormalities
Synonym: B lymphocyte abnormalities
Synonym: immune system: lymphoid development/ B lymphocyte defects
MP id: MP:0002144
Alternate id: MP:0001801, MP:0002438, MP:0001803
Definition: atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal B cell morphology
                                                                        is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                                                is-aabnormal B cell activation +
                                                                                is-aabnormal B cell receptor editing
                                                                                is-aabnormal B cell selection +
                                                                                is-aabnormal class switch recombination
                                                                                is-aabnormal immature B cell morphology +
                                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                                is-aabnormal memory B cell differentiation
                                                                                is-aabnormal plasma cell differentiation
                                                                                is-aabnormal pro-B cell morphology +
                                                                                is-aabnormal somatic hypermutation frequency
                                                                                is-aarrested B cell differentiation
                                                                        is-aabnormal B cell number +
                                                                        is-aabnormal immature B cell morphology +
                                                                        is-aabnormal mature B cell morphology +
                                                                        is-aabnormal plasma cell morphology +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukocyte morphology
                                                is-aabnormal mononuclear cell morphology
                                                        is-aabnormal lymphocyte morphology
                                                                is-aabnormal lymphopoiesis
                                                                        is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                                                is-aabnormal B cell activation +
                                                                                is-aabnormal B cell receptor editing
                                                                                is-aabnormal B cell selection +
                                                                                is-aabnormal class switch recombination
                                                                                is-aabnormal immature B cell morphology +
                                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                                is-aabnormal memory B cell differentiation
                                                                                is-aabnormal plasma cell differentiation
                                                                                is-aabnormal pro-B cell morphology +
                                                                                is-aabnormal somatic hypermutation frequency
                                                                                is-aarrested B cell differentiation
                                                                        is-aabnormal NK cell differentiation
                                                                        is-aabnormal T cell differentiation +


mammalian phenotype
        is-ahematopoietic system phenotype
                is-aabnormal hematopoietic system morphology/development
                        is-aabnormal blood cell morphology/development
                                is-aabnormal hematopoiesis
                                        is-aabnormal leukopoiesis
                                                is-aabnormal lymphopoiesis
                                                        is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                                is-aabnormal B cell activation +
                                                                is-aabnormal B cell receptor editing
                                                                is-aabnormal B cell selection +
                                                                is-aabnormal class switch recombination
                                                                is-aabnormal immature B cell morphology +
                                                                is-aabnormal immunoglobulin V(D)J recombination +
                                                                is-aabnormal memory B cell differentiation
                                                                is-aabnormal plasma cell differentiation
                                                                is-aabnormal pro-B cell morphology +
                                                                is-aabnormal somatic hypermutation frequency
                                                                is-aarrested B cell differentiation
                                                        is-aabnormal NK cell differentiation
                                                        is-aabnormal T cell differentiation +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal B cell morphology
                                                                is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                                        is-aabnormal B cell activation +
                                                                        is-aabnormal B cell receptor editing
                                                                        is-aabnormal B cell selection +
                                                                        is-aabnormal class switch recombination
                                                                        is-aabnormal immature B cell morphology +
                                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                                        is-aabnormal memory B cell differentiation
                                                                        is-aabnormal plasma cell differentiation
                                                                        is-aabnormal pro-B cell morphology +
                                                                        is-aabnormal somatic hypermutation frequency
                                                                        is-aarrested B cell differentiation
                                                                is-aabnormal B cell number +
                                                                is-aabnormal immature B cell morphology +
                                                                is-aabnormal mature B cell morphology +
                                                                is-aabnormal plasma cell morphology +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukocyte morphology
                                        is-aabnormal mononuclear cell morphology
                                                is-aabnormal lymphocyte morphology
                                                        is-aabnormal lymphopoiesis
                                                                is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                                        is-aabnormal B cell activation +
                                                                        is-aabnormal B cell receptor editing
                                                                        is-aabnormal B cell selection +
                                                                        is-aabnormal class switch recombination
                                                                        is-aabnormal immature B cell morphology +
                                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                                        is-aabnormal memory B cell differentiation
                                                                        is-aabnormal plasma cell differentiation
                                                                        is-aabnormal pro-B cell morphology +
                                                                        is-aabnormal somatic hypermutation frequency
                                                                        is-aarrested B cell differentiation
                                                                is-aabnormal NK cell differentiation
                                                                is-aabnormal T cell differentiation +


mammalian phenotype
        is-aimmune system phenotype
                is-aabnormal immune system morphology
                        is-aabnormal immune system cell morphology
                                is-aabnormal leukopoiesis
                                        is-aabnormal lymphopoiesis
                                                is-aabnormal B cell differentiation [MP:0002144] (1096 genotypes, 1847 annotations)
                                                        is-aabnormal B cell activation +
                                                        is-aabnormal B cell receptor editing
                                                        is-aabnormal B cell selection +
                                                        is-aabnormal class switch recombination
                                                        is-aabnormal immature B cell morphology +
                                                        is-aabnormal immunoglobulin V(D)J recombination +
                                                        is-aabnormal memory B cell differentiation
                                                        is-aabnormal plasma cell differentiation
                                                        is-aabnormal pro-B cell morphology +
                                                        is-aabnormal somatic hypermutation frequency
                                                        is-aarrested B cell differentiation
                                                is-aabnormal NK cell differentiation
                                                is-aabnormal T cell differentiation +

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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory