| MP term: | arrested B cell differentiation |
| Synonym: | arrested B cell development |
| Synonym: | arrested B-cell development |
| Synonym: | arrested B lymphocyte development |
| Synonym: | failed B cell maturation |
| Synonym: | failed B-cell maturation |
| Synonym: | failed B lymphocyte maturation |
| Synonym: | failure of B cell maturation |
| Synonym: | failure of B-cell maturation |
| Synonym: | failure of B lymphocyte maturation |
| MP id: | MP:0001802 |
| Alternate id: | MP:0002457 |
| Definition: | inability to produce mature B cells, and accumulation of B cell precursors |
| Number of paths to term: | 12 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
cellular phenotypeabnormal cell physiologyabnormal cell differentiationabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal hematopoiesisabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal blood cell morphology/developmentabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)hematopoietic system phenotypeabnormal hematopoietic system morphology/developmentabnormal bone marrow cell morphology/developmentabnormal myeloblast morphology/developmentabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal B cell morphologyabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukocyte morphologyabnormal mononuclear cell morphologyabnormal lymphocyte morphologyabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)immune system phenotypeabnormal immune system morphologyabnormal immune system cell morphologyabnormal leukopoiesisabnormal mononuclear cell differentiationabnormal lymphopoiesisabnormal B cell differentiationabnormal B cell activation +abnormal B cell receptor editingabnormal B cell selection +abnormal class switch recombinationabnormal immature B cell morphology +abnormal immunoglobulin V(D)J recombination +abnormal memory B cell differentiationabnormal plasma cell differentiationabnormal pro-B cell morphology +abnormal somatic hypermutation frequencyarrested B cell differentiation [MP:0001802] (127 genotypes, 127 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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