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Mammalian Phenotype Browser
Term Detail
MP term:abnormal apical ectodermal ridge morphology
Synonym: abnormal AER
MP id: MP:0001676
Definition: any structural anomaly of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal developmental patterning
                                is-aabnormal gastrulation
                                        is-aabnormal triploblastic development
                                                is-aabnormal ectoderm development
                                                        is-aabnormal apical ectodermal ridge morphology [MP:0001676] (54 genotypes, 60 annotations)
                                                                is-aabsent apical ectodermal ridge
                                                                is-athick apical ectodermal ridge
                                                                is-athin apical ectodermal ridge
                                                        is-aabnorrmal surface ectoderm morphology
                                                        is-aabsent ectoderm
                                                        is-aincreased ectoderm apoptosis


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal limb bud morphology
                                        is-aabnormal apical ectodermal ridge morphology [MP:0001676] (54 genotypes, 60 annotations)
                                                is-aabsent apical ectodermal ridge
                                                is-athick apical ectodermal ridge
                                                is-athin apical ectodermal ridge
                                        is-aabnormal forelimb bud morphology +
                                        is-aabnormal hindlimb bud morphology +
                                        is-aabnormal limb mesenchyme morphology
                                        is-aabnormal zone of polarizing activity morphology
                                        is-aabsent limb buds +
                                        is-abroad limb buds
                                        is-asmall limb buds +


mammalian phenotype
        is-aembryogenesis phenotype
                is-aabnormal embryogenesis/ development
                        is-aabnormal embryonic tissue morphology
                                is-aabnormal triploblastic development
                                        is-aabnormal ectoderm development
                                                is-aabnormal apical ectodermal ridge morphology [MP:0001676] (54 genotypes, 60 annotations)
                                                        is-aabsent apical ectodermal ridge
                                                        is-athick apical ectodermal ridge
                                                        is-athin apical ectodermal ridge
                                                is-aabnorrmal surface ectoderm morphology
                                                is-aabsent ectoderm
                                                is-aincreased ectoderm apoptosis


mammalian phenotype
        is-alimbs/digits/tail phenotype
                is-aabnormal limb morphology
                        is-aabnormal limb development
                                is-aabnormal limb bud morphology
                                        is-aabnormal apical ectodermal ridge morphology [MP:0001676] (54 genotypes, 60 annotations)
                                                is-aabsent apical ectodermal ridge
                                                is-athick apical ectodermal ridge
                                                is-athin apical ectodermal ridge
                                        is-aabnormal forelimb bud morphology +
                                        is-aabnormal hindlimb bud morphology +
                                        is-aabnormal limb mesenchyme morphology
                                        is-aabnormal zone of polarizing activity morphology
                                        is-aabsent limb buds +
                                        is-abroad limb buds
                                        is-asmall limb buds +

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory