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Mammalian Phenotype Browser
Term Detail
MP term:motor neuron degeneration
Synonym: loss of motor neurons
Synonym: motoneuron degeneration
MP id: MP:0000938
Definition: retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aabnormal motor neuron morphology
                                        is-aabnormal motor neuron innervation
                                        is-adecreased motor neuron number
                                        is-aincreased motor neuron number
                                        is-amotor neuron degeneration [MP:0000938] (87 genotypes, 87 annotations)

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal neuron morphology
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration [MP:0000938] (87 genotypes, 87 annotations)
                                        is-aPurkinje cell degeneration
                                        is-aretinal ganglion cell degeneration
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal spinal cord morphology
                                is-aabnormal spinal cord grey matter morphology
                                        is-aabnormal motor neuron morphology
                                                is-aabnormal motor neuron innervation
                                                is-adecreased motor neuron number
                                                is-aincreased motor neuron number
                                                is-amotor neuron degeneration [MP:0000938] (87 genotypes, 87 annotations)

mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aneurodegeneration
                                is-aneuron degeneration
                                        is-aamacrine cell degeneration
                                        is-acochlear hair cell degeneration +
                                        is-ahippocampal neuron degeneration
                                        is-amotor neuron degeneration [MP:0000938] (87 genotypes, 87 annotations)
                                        is-aPurkinje cell degeneration
                                        is-aretinal ganglion cell degeneration
                                        is-aretinal photoreceptor degeneration +
                                        is-avestibular hair cell degeneration
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
06/05/2013
MGI 5.13 		The Jackson Laboratory