| MP term: | abnormal roof plate morphology |
| Synonym: | roof plate abnormalities |
| Synonym: | roof plate dysplasia |
| MP id: | MP:0000923 |
| Definition: | any structural anomaly of a transient group of neuroepithelial cells located at the dorsal midline of the neural tube that profoundly influences the development of the vertebrate central nervous system |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
embryogenesis phenotypeabnormal embryogenesis/ developmentabnormal embryonic tissue morphologyabnormal neural tube morphology/developmentabnormal embryonic neuroepithelium morphology +abnormal floor plate morphology +abnormal neural crest morphology +abnormal neural tube closure +abnormal neural tube mantle layer morphology +abnormal neural tube marginal layer morphologyabnormal neural tube ventricular layer morphologyabnormal neuromere morphology +abnormal roof plate morphology [MP:0000923] (12 genotypes, 12 annotations)absent roof platecaudal rachischisiscraniorachischisiskinked neural tubewavy neural tubenervous system phenotypeabnormal nervous system morphologyabnormal nervous system developmentabnormal neural tube morphology/developmentabnormal embryonic neuroepithelium morphology +abnormal floor plate morphology +abnormal neural crest morphology +abnormal neural tube closure +abnormal neural tube mantle layer morphology +abnormal neural tube marginal layer morphologyabnormal neural tube ventricular layer morphologyabnormal neuromere morphology +abnormal roof plate morphology [MP:0000923] (12 genotypes, 12 annotations)absent roof platecaudal rachischisiscraniorachischisiskinked neural tubewavy neural tubeMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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