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Mammalian Phenotype Browser
Term Detail
MP term:abnormal myelination
Synonym: absence of myelination
Synonym: absent myelination
Synonym: altered myelination
Synonym: myelination abnormalities
Synonym: myelination defect
MP id: MP:0000920
Alternate id: MP:0001894, MP:0010051
Definition: any anomaly in the process by which myelin sheaths are formed and maintained around neurons; oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system physiology
                        is-aabnormal autonomic nervous system physiology +
                        is-aabnormal blood-brain barrier function
                        is-aabnormal blood-cerebrospinal fluid barrier function
                        is-aabnormal central pattern generator function +
                        is-aabnormal cerebrospinal fluid production +
                        is-aabnormal dopamine level +
                        is-aabnormal embryonic neuroepithelial cell proliferation +
                        is-aabnormal endoneurial fluid pressure +
                        is-aabnormal ependyma motile cilium physiology +
                        is-aabnormal glial cell physiology +
                        is-aabnormal hippocampus physiology
                        is-aabnormal hypothalamus physiology +
                        is-aabnormal myelination [MP:0000920] (378 genotypes, 405 annotations)
                                is-ademyelination
                                is-ahypermyelination
                        is-aabnormal nervous system electrophysiology +
                        is-aabnormal nervous system regeneration +
                        is-aabnormal neuron physiology +
                        is-aabnormal neuronal stem cell physiology +
                        is-aabnormal pineal gland physiology +
                        is-aabnormal pituitary gland physiology +
                        is-aabnormal sensorimotor gating +
                        is-aabnormal somatic nervous system physiology +
                        is-aabnormal somatosensory cortex physiology +
                        is-aabnormal synaptic plasticity +
                        is-aabnormal synaptic transmission +
                        is-aaltered response to CNS ischemic injury +
                        is-aCNS inflammation +
                        is-aCNS ischemia
                        is-adecreased hindbrain apoptosis
                        is-aendoneurial edema
                        is-aincreased forebrain apoptosis
                        is-aincreased hindbrain apoptosis
                        is-aincreased midbrain apoptosis
                        is-aincreased neural tube apoptosis +
                        is-aincreased spinal cord apoptosis
                        is-aintracranial hemorrhage +
                        is-aseizures +
                        is-aspinal hemorrhage

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory