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Mammalian Phenotype Browser
Term Detail
MP term:abnormal hypothalamus morphology
Synonym: hypothalamus dysplasia
MP id: MP:0000837
Definition: any structural anomaly of the ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle; this region regulates the autonomic nervous system via hormone production and release
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal forebrain morphology
                                        is-aabnormal diencephalon morphology
                                                is-aabnormal epithalamus morphology +
                                                is-aabnormal globus pallidus morphology
                                                is-aabnormal hypothalamus morphology [MP:0000837] (58 genotypes, 65 annotations)
                                                        is-aabnormal anterior hypothalamic nucleus morphology
                                                        is-aabnormal magnocellular neurosecretory cell morphology +
                                                        is-aabnormal median eminence morphology
                                                        is-aabnormal paraventricular hypothalamic nucleus morphology +
                                                        is-aabnormal suprachiasmatic nucleus morphology
                                                        is-aabnormal supraoptic nucleus morphology
                                                        is-adecreased hypothalamus hypoxanthine-guanine phosphoribosyltransferase level
                                                        is-ahypothalamus hyperplasia
                                                        is-aincreased hypothalamus hypoxanthine-guanine phosphoribosyltransferase level
                                                is-aabnormal mammillary body morphology
                                                is-aabnormal pituitary gland morphology +
                                                is-aabnormal subthalamus morphology +
                                                is-aabnormal thalamus morphology +
                                                is-aabnormal third ventricle morphology +
                                                is-aabsent diencephalon
                                                is-adiencephalon hyperplasia
                                                is-adiencephalon hypoplasia


mammalian phenotype
        is-anervous system phenotype
                is-aabnormal nervous system morphology
                        is-aabnormal brain morphology
                                is-aabnormal forebrain morphology
                                        is-aabnormal limbic system morphology
                                                is-aabnormal amygdala morphology +
                                                is-aabnormal fornicate gyrus morphology +
                                                is-aabnormal hippocampus morphology +
                                                is-aabnormal hypothalamus morphology [MP:0000837] (58 genotypes, 65 annotations)
                                                        is-aabnormal anterior hypothalamic nucleus morphology
                                                        is-aabnormal magnocellular neurosecretory cell morphology +
                                                        is-aabnormal median eminence morphology
                                                        is-aabnormal paraventricular hypothalamic nucleus morphology +
                                                        is-aabnormal suprachiasmatic nucleus morphology
                                                        is-aabnormal supraoptic nucleus morphology
                                                        is-adecreased hypothalamus hypoxanthine-guanine phosphoribosyltransferase level
                                                        is-ahypothalamus hyperplasia
                                                        is-aincreased hypothalamus hypoxanthine-guanine phosphoribosyltransferase level
                                                is-aabnormal nucleus accumbens morphology +
                                                is-aabnormal orbitofrontal cortex morphology

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory