About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:regulation of spindle checkpoint
GO id:GO:0090231
Definition:Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
CommentsNote that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
Number of paths to term: 17

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        regulatesregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        is-aspindle checkpoint
                                                                part-ofdetection of stimulus involved in spindle checkpoint +
                                                                is-ameiotic spindle checkpoint +
                                                                is-amitotic spindle checkpoint +
                                                                negatively-regulatesnegative regulation of spindle checkpoint +
                                                                positively-regulatespositive regulation of spindle checkpoint +
                                                                regulatesregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +
                                                                part-ofsignal transduction involved in spindle checkpoint +
                                                                is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                regulatesregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                is-aspindle checkpoint
                                                        part-ofdetection of stimulus involved in spindle checkpoint +
                                                        is-ameiotic spindle checkpoint +
                                                        is-amitotic spindle checkpoint +
                                                        negatively-regulatesnegative regulation of spindle checkpoint +
                                                        positively-regulatespositive regulation of spindle checkpoint +
                                                        regulatesregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +
                                                        part-ofsignal transduction involved in spindle checkpoint +
                                                        is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        regulatesregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        is-aspindle checkpoint
                                                                part-ofdetection of stimulus involved in spindle checkpoint +
                                                                is-ameiotic spindle checkpoint +
                                                                is-amitotic spindle checkpoint +
                                                                negatively-regulatesnegative regulation of spindle checkpoint +
                                                                positively-regulatespositive regulation of spindle checkpoint +
                                                                regulatesregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +
                                                                part-ofsignal transduction involved in spindle checkpoint +
                                                                is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                regulatesregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                is-aspindle checkpoint
                                                        part-ofdetection of stimulus involved in spindle checkpoint +
                                                        is-ameiotic spindle checkpoint +
                                                        is-amitotic spindle checkpoint +
                                                        negatively-regulatesnegative regulation of spindle checkpoint +
                                                        positively-regulatespositive regulation of spindle checkpoint +
                                                        regulatesregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +
                                                        part-ofsignal transduction involved in spindle checkpoint +
                                                        is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (15 genes, 18 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/20/2015
MGI 5.22
The Jackson Laboratory