About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:regulation of spindle checkpoint
GO id:GO:0090231
Definition:Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
Number of paths to term: 17

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        regulatesregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        is-aspindle checkpoint
                                                                part-ofdetection of stimulus involved in spindle checkpoint +
                                                                is-ameiotic spindle checkpoint +
                                                                is-amitotic spindle checkpoint +
                                                                negatively-regulatesnegative regulation of spindle checkpoint +
                                                                positively-regulatespositive regulation of spindle checkpoint +
                                                                regulatesregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +
                                                                part-ofsignal transduction involved in spindle checkpoint +
                                                                is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                regulatesregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                is-aspindle checkpoint
                                                        part-ofdetection of stimulus involved in spindle checkpoint +
                                                        is-ameiotic spindle checkpoint +
                                                        is-amitotic spindle checkpoint +
                                                        negatively-regulatesnegative regulation of spindle checkpoint +
                                                        positively-regulatespositive regulation of spindle checkpoint +
                                                        regulatesregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +
                                                        part-ofsignal transduction involved in spindle checkpoint +
                                                        is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        regulatesregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle checkpoint
                                                        is-aspindle checkpoint
                                                                part-ofdetection of stimulus involved in spindle checkpoint +
                                                                is-ameiotic spindle checkpoint +
                                                                is-amitotic spindle checkpoint +
                                                                negatively-regulatesnegative regulation of spindle checkpoint +
                                                                positively-regulatespositive regulation of spindle checkpoint +
                                                                regulatesregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +
                                                                part-ofsignal transduction involved in spindle checkpoint +
                                                                is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle checkpoint
                                                                is-anegative regulation of cell cycle checkpoint +
                                                                is-apositive regulation of cell cycle checkpoint +
                                                                is-aregulation of DNA damage checkpoint +
                                                                is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                        is-anegative regulation of spindle checkpoint +
                                                                        is-apositive regulation of spindle checkpoint +
                                                                        is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                regulatesregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle checkpoint
                                                is-aspindle checkpoint
                                                        part-ofdetection of stimulus involved in spindle checkpoint +
                                                        is-ameiotic spindle checkpoint +
                                                        is-amitotic spindle checkpoint +
                                                        negatively-regulatesnegative regulation of spindle checkpoint +
                                                        positively-regulatespositive regulation of spindle checkpoint +
                                                        regulatesregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +
                                                        part-ofsignal transduction involved in spindle checkpoint +
                                                        is-aspindle assembly checkpoint +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle checkpoint
                                                        is-anegative regulation of cell cycle checkpoint +
                                                        is-apositive regulation of cell cycle checkpoint +
                                                        is-aregulation of DNA damage checkpoint +
                                                        is-aregulation of spindle checkpoint [GO:0090231] (14 genes, 17 annotations)
                                                                is-anegative regulation of spindle checkpoint +
                                                                is-apositive regulation of spindle checkpoint +
                                                                is-aregulation of mitotic spindle checkpoint +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory