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Gene Ontology Browser
Term Detail
GO term:phospholipase C-activating adrenergic receptor signaling pathway
Synonym: activation of phospholipase C activity by adrenergic receptor signaling pathway
Synonym: activation of phospholipase C activity by adrenergic receptor signalling pathway
Synonym: adrenergic receptor, phospholipase C activating pathway
GO id:GO:0071882
Definition:The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
Number of paths to term: 18

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway
                                                                        is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                        is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                        is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                        is-aadrenergic receptor signaling pathway involved in heart process +
                                                                        negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                        regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway
                                                                        is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                        is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                        is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                        is-aadrenergic receptor signaling pathway involved in heart process +
                                                                        negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                        regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aadrenergic receptor signaling pathway
                                                                is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                is-aadrenergic receptor signaling pathway involved in heart process +
                                                                negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aadrenergic receptor signaling pathway
                                                                        is-aactivation of MAPK activity by adrenergic receptor signaling pathway
                                                                        is-aadenylate cyclase-activating adrenergic receptor signaling pathway +
                                                                        is-aadenylate cyclase-inhibiting adrenergic receptor signaling pathway +
                                                                        is-aadrenergic receptor signaling pathway involved in heart process +
                                                                        negatively-regulatesnegative regulation of adrenergic receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        positively-regulatespositive regulation of adrenergic receptor signaling pathway +
                                                                        regulatesregulation of adrenergic receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aphospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        negatively-regulatesnegative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway +
                                                                        is-aphospholipase C-activating adrenergic receptor signaling pathway [GO:0071882] (1 genes, 1 annotations)
                                                                        is-aphospholipase C-activating angiotensin-activated signaling pathway +
                                                                        is-aphospholipase C-activating dopamine receptor signaling pathway +
                                                                        is-aphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
                                                                        is-aphospholipase C-activating G-protein coupled glutamate receptor signaling pathway
                                                                        is-aphospholipase C-activating rhodopsin mediated signaling pathway
                                                                        is-aphospholipase C-activating serotonin receptor signaling pathway
                                                                        is-aphospholipase C-activating tachykinin receptor signaling pathway
                                                                        part-ofpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
                                                                        positively-regulatespositive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
                                                                        regulatesregulation of phospholipase C-activating G-protein coupled receptor signaling pathway +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory