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Gene Ontology Browser
Term Detail
GO term:smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Synonym: hedgehog signaling pathway involved in dorsal/ventral neural tube patterning
Synonym: hh signaling pathway involved in dorsal/ventral neural tube patterning
Synonym: smoothened signalling pathway involved in dorsal/ventral neural tube patterning
GO id:GO:0060831
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
Number of paths to term: 46

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-asmoothened signaling pathway
                                                                part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                                is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                                positively-regulatespositive regulation of smoothened signaling pathway +
                                                                regulatesregulation of smoothened signaling pathway +
                                                                part-ofsignal transduction downstream of smoothened +
                                                                is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                is-asmoothened signaling pathway involved in lung development
                                                                is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-asmoothened signaling pathway
                                                                part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                                is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                                positively-regulatespositive regulation of smoothened signaling pathway +
                                                                regulatesregulation of smoothened signaling pathway +
                                                                part-ofsignal transduction downstream of smoothened +
                                                                is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                is-asmoothened signaling pathway involved in lung development
                                                                is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aembryo development
                                        is-aembryo development ending in birth or egg hatching
                                                is-achordate embryonic development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aneural tube development
                                        part-ofneural tube patterning
                                                part-ofdorsal/ventral neural tube patterning
                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        is-anervous system development
                                                part-ofneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-aepithelium development
                                                is-aneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atube development
                                        is-aneural tube development
                                                part-ofneural tube patterning
                                                        part-ofdorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-aembryo development
                                        is-aembryo development ending in birth or egg hatching
                                                is-achordate embryonic development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofembryo development
                                                is-aembryo development ending in birth or egg hatching
                                                        is-achordate embryonic development
                                                                part-ofneural tube development
                                                                        part-ofneural tube patterning
                                                                                part-ofdorsal/ventral neural tube patterning
                                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-adorsal/ventral pattern formation
                                                                is-adorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-aneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-oftube development
                                                is-aneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-aneural tube development
                                        part-ofneural tube patterning
                                                part-ofdorsal/ventral neural tube patterning
                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-apattern specification process
                                        is-aregionalization
                                                is-adorsal/ventral pattern formation
                                                        is-adorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-apattern specification process
                                        is-aregionalization
                                                is-aneural tube patterning
                                                        part-ofdorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofembryo development
                                                is-aembryo development ending in birth or egg hatching
                                                        is-achordate embryonic development
                                                                part-ofneural tube development
                                                                        part-ofneural tube patterning
                                                                                part-ofdorsal/ventral neural tube patterning
                                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-adorsal/ventral pattern formation
                                                                is-adorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-aneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-oftube development
                                                is-aneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-apattern specification process
                                        is-aregionalization
                                                is-adorsal/ventral pattern formation
                                                        is-adorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-apattern specification process
                                        is-aregionalization
                                                is-aneural tube patterning
                                                        part-ofdorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-asmoothened signaling pathway
                                                        part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                        is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                        positively-regulatespositive regulation of smoothened signaling pathway +
                                                        regulatesregulation of smoothened signaling pathway +
                                                        part-ofsignal transduction downstream of smoothened +
                                                        is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        is-asmoothened signaling pathway involved in lung development
                                                        is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofembryo development
                                                is-aembryo development ending in birth or egg hatching
                                                        is-achordate embryonic development
                                                                part-ofneural tube development
                                                                        part-ofneural tube patterning
                                                                                part-ofdorsal/ventral neural tube patterning
                                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-adorsal/ventral pattern formation
                                                                is-adorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-aneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-oftube development
                                                is-aneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-apattern specification process
                                        is-aregionalization
                                                is-adorsal/ventral pattern formation
                                                        is-adorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-apattern specification process
                                        is-aregionalization
                                                is-aneural tube patterning
                                                        part-ofdorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-asmoothened signaling pathway
                                                                part-ofciliary receptor clustering involved in smoothened signaling pathway
                                                                is-amesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway +
                                                                positively-regulatespositive regulation of smoothened signaling pathway +
                                                                regulatesregulation of smoothened signaling pathway +
                                                                part-ofsignal transduction downstream of smoothened +
                                                                is-asmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                is-asmoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                is-asmoothened signaling pathway involved in lung development
                                                                is-asmoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                is-asmoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                is-asmoothened signaling pathway involved in ventral spinal cord patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-aembryo development
                                        is-aembryo development ending in birth or egg hatching
                                                is-achordate embryonic development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofembryo development
                                                is-aembryo development ending in birth or egg hatching
                                                        is-achordate embryonic development
                                                                part-ofneural tube development
                                                                        part-ofneural tube patterning
                                                                                part-ofdorsal/ventral neural tube patterning
                                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-adorsal/ventral pattern formation
                                                                is-adorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofpattern specification process
                                                is-aregionalization
                                                        is-aneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                is-anervous system development
                                                        part-ofneural tube development
                                                                part-ofneural tube patterning
                                                                        part-ofdorsal/ventral neural tube patterning
                                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-oftube development
                                                is-aneural tube development
                                                        part-ofneural tube patterning
                                                                part-ofdorsal/ventral neural tube patterning
                                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-aneural tube development
                                        part-ofneural tube patterning
                                                part-ofdorsal/ventral neural tube patterning
                                                        part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-apattern specification process
                                        is-aregionalization
                                                is-adorsal/ventral pattern formation
                                                        is-adorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-apattern specification process
                                        is-aregionalization
                                                is-aneural tube patterning
                                                        part-ofdorsal/ventral neural tube patterning
                                                                part-ofsmoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:0060831] (12 genes, 14 annotations)
                                                                        negatively-regulatesnegative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        positively-regulatespositive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
                                                                        regulatesregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory