| GO term: | kinetochore assembly |
| Synonym: | centromere and kinetochore complex maturation |
| Synonym: | centromere/kinetochore complex maturation |
| Synonym: | chromosome-kinetochore attachment |
| Synonym: | kinetochore biogenesis |
| Synonym: | kinetochore biosynthesis |
| Synonym: | kinetochore formation |
| GO id: | GO:0051382 |
| Definition: | The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
| Number of paths to term: | 24 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processcellular component organization or biogenesiscellular component biogenesiscellular component assemblymacromolecular complex assemblycellular macromolecular complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component biogenesiscellular component assemblymacromolecular complex assemblycellular macromolecular complex assemblyprotein-DNA complex assemblycentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular component organization or biogenesiscellular component biogenesiscellular component assemblymacromolecular complex assemblyprotein complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component biogenesiscellular component assemblyorganelle assemblyautophagic vacuole assembly +CVT vesicle assemblyextracellular vesicular exosome assemblyfemale pronucleus assemblykaryomere assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblymale pronucleus assembly +multivesicular body assemblyphagolysosome assembly +ribosome assembly +spindle assembly +biological_processcellular component organization or biogenesiscellular component biogenesisprotein complex biogenesisprotein complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationcellular component assemblymacromolecular complex assemblycellular macromolecular complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationcellular component assemblymacromolecular complex assemblycellular macromolecular complex assemblyprotein-DNA complex assemblycentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular component organization or biogenesiscellular component organizationcellular component assemblymacromolecular complex assemblyprotein complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationcellular component assemblyorganelle assemblyautophagic vacuole assembly +CVT vesicle assemblyextracellular vesicular exosome assemblyfemale pronucleus assemblykaryomere assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblymale pronucleus assembly +multivesicular body assemblyphagolysosome assembly +ribosome assembly +spindle assembly +biological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationmacromolecular complex assemblycellular macromolecular complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationmacromolecular complex assemblycellular macromolecular complex assemblyprotein-DNA complex assemblycentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationmacromolecular complex assemblyprotein complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationprotein complex subunit organizationkinetochore organizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblybiological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationprotein complex subunit organizationprotein complex assemblycellular protein complex assemblyactivation of transmembrane receptor protein tyrosine kinase activityaxonemal dynein complex assembly +cargo loading into vesicle +chaperone-mediated protein complex assembly +clathrin coat assembly +cytochrome complex assembly +eukaryotic translation initiation factor 3 complex assemblyeukaryotic translation initiation factor 4F complex assemblyexocyst assembly +GINS complex assemblyGolgi membrane coat protein complex assemblyGolgi membrane priming complex assemblyGolgi vesicle prefusion complex stabilizationJAK-induced STAT protein dimerizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyMCM complex assemblymediator complex assembly +MHC protein complex assembly +mitochondrial outer membrane translocase complex assemblymitochondrial respiratory chain complex assembly +mitochondrial respiratory chain supercomplex assemblyMre11 complex assemblymyosin filament assembly +NAD(P)H dehydrogenase complex assemblyNADH dehydrogenase complex assembly +NLRP3 inflammasome complex assembly +nodal receptor complex assembly +nuclear pore complex assembly +peptide antigen assembly with MHC protein complex +photosystem I assemblyphotosystem II assembly +posttranslational protein targeting to membrane, dockingproteasome assembly +protein catenane formation +protein import into nucleus, dockingprotein import into peroxisome matrix, dockingprotein polymerization +proton-transporting two-sector ATPase complex assembly +respiratory chain complex II assembly +respiratory chain complex IV assembly +SAGA complex assemblySCF complex assemblyseptin ring assemblysignal complex assemblysignalosome assemblySMAD protein complex assembly +SNARE complex assembly +spindle midzone assembly +SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionsteroid hormone receptor complex assemblysynaptic vesicle priming +transcription factor TFIIIB complex assemblytransforming growth factor beta receptor complex assemblytubulin complex assemblyvoltage-gated calcium channel complex assemblybiological_processcellular component organization or biogenesiscellular component organizationmacromolecular complex subunit organizationprotein-DNA complex subunit organizationprotein-DNA complex assemblycentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular component organization or biogenesiscellular component organizationorganelle organizationchromosome organizationcentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular component organization or biogenesiscellular component organizationorganelle organizationchromosome organizationkinetochore organizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblybiological_processcellular component organization or biogenesiscellular component organizationorganelle organizationorganelle assemblyautophagic vacuole assembly +CVT vesicle assemblyextracellular vesicular exosome assemblyfemale pronucleus assemblykaryomere assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblymale pronucleus assembly +multivesicular body assemblyphagolysosome assembly +ribosome assembly +spindle assembly +biological_processcellular processsingle-organism cellular processorganelle organizationchromosome organizationcentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processcellular processsingle-organism cellular processorganelle organizationchromosome organizationkinetochore organizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblybiological_processcellular processsingle-organism cellular processorganelle organizationorganelle assemblyautophagic vacuole assembly +CVT vesicle assemblyextracellular vesicular exosome assemblyfemale pronucleus assemblykaryomere assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblymale pronucleus assembly +multivesicular body assemblyphagolysosome assembly +ribosome assembly +spindle assembly +biological_processsingle-organism processsingle-organism cellular processorganelle organizationchromosome organizationcentromere complex assemblyCENP-A containing nucleosome assembly at centromerecentromeric heterochromatin assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblyregulation of centromere complex assembly +biological_processsingle-organism processsingle-organism cellular processorganelle organizationchromosome organizationkinetochore organizationkinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblybiological_processsingle-organism processsingle-organism cellular processorganelle organizationorganelle assemblyautophagic vacuole assembly +CVT vesicle assemblyextracellular vesicular exosome assemblyfemale pronucleus assemblykaryomere assemblykinetochore assembly [GO:0051382] (8 genes, 8 annotations)regulation of kinetochore assemblymale pronucleus assembly +multivesicular body assemblyphagolysosome assembly +ribosome assembly +spindle assembly +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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