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Gene Ontology Browser
Term Detail
GO term:cofactor binding
GO id:GO:0048037
Definition:Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-a2-aminoethylphosphonate binding
                        is-aacyl binding
                        is-aalkene binding +
                        is-aamide binding +
                        is-aamine binding +
                        is-aantigen binding +
                        is-abinding, bridging +
                        is-acalcium oxalate binding
                        is-acarbohydrate binding +
                        is-acarbohydrate derivative binding +
                        is-acarbon dioxide binding
                        is-acofactor binding [GO:0048037] (262 genes, 367 annotations)
                                is-acoenzyme binding +
                                is-ahydroquinone binding
                                is-airon-sulfur-molybdenum cofactor binding
                                is-aprosthetic group binding +
                                is-apyridoxal phosphate binding
                                is-aquinone binding +
                        is-adinitrosyl-iron complex binding
                        is-adrug binding +
                        is-aextracellular matrix binding +
                        is-afatty acid derivative binding +
                        is-aflavonoid binding +
                        is-aflurbiprofen binding
                        is-aheterocyclic compound binding +
                        is-ahormone binding +
                        is-ahost cell surface binding +
                        is-ahydroxyapatite binding
                        is-aion binding +
                        is-alipid binding +
                        is-amacromolecular complex binding +
                        is-ametal cluster binding +
                        is-aMgATP(2-) binding
                        is-amicrofibril binding
                        is-amodified amino acid binding +
                        is-aneurotransmitter binding +
                        is-anitric oxide binding +
                        is-aodorant binding +
                        is-aorganic cyclic compound binding +
                        is-aoxygen binding +
                        is-apattern binding +
                        is-apigment binding +
                        is-aplatinum binding
                        is-apoly(3-hydroxyalkanoate) binding
                        is-apolyamine binding +
                        is-aprotein binding +
                        is-aquaternary ammonium group binding +
                        is-aselenium binding
                        is-asmall molecule binding +
                        is-asulfur compound binding +
                        is-asynthetic cannabinoid binding
                        is-atetrahydrofolyl-poly(glutamate) polymer binding
                        is-atoxic substance binding
                        is-avirion binding
                        is-awater binding +
                        is-axenon atom binding


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory