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Gene Ontology Browser
Term Detail
GO term:lactosylceramide alpha-2,3-sialyltransferase activity
Synonym: CMP-acetylneuraminate-lactosylceramide-sialyltransferase
Synonym: CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity
Synonym: CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity
Synonym: CMP-sialic acid:lactosylceramide-sialyltransferase activity
Synonym: cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity
Synonym: cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase
Synonym: ganglioside GM3 synthase activity
Synonym: ganglioside GM3 synthetase activity
Synonym: GM3 synthase activity
Synonym: GM3 synthetase activity
Synonym: SAT 1
GO id:GO:0047291
Definition:Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring glycosyl groups
                                        is-asialyltransferase activity
                                                is-a(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity
                                                is-aalpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
                                                is-aalpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
                                                is-abeta-galactoside (CMP) alpha-2,3-sialyltransferase activity
                                                is-abeta-galactoside alpha-2,3-sialyltransferase activity
                                                is-abeta-galactoside alpha-2,6-sialyltransferase activity
                                                is-agalactosyldiacylglycerol alpha-2,3-sialyltransferase activity
                                                is-alactosylceramide alpha-2,3-sialyltransferase activity [GO:0047291] (1 genes, 1 annotations)
                                                is-alactosylceramide alpha-2,6-N-sialyltransferase activity
                                                is-amonosialoganglioside sialyltransferase activity
                                                is-aN-acetyllactosaminide alpha-2,3-sialyltransferase activity
                                                is-aneolactotetraosylceramide alpha-2,3-sialyltransferase activity
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory