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Gene Ontology Browser
Term Detail
GO term:phospholipid translocation
Synonym: flippase
GO id:GO:0045332
Definition:The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
CommentsNote that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.
Number of paths to term: 25

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-aregulation of membrane lipid distribution
                                        is-alipid translocation
                                                is-aglycolipid translocation
                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                        positively-regulatespositive regulation of phospholipid translocation
                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-acellular component organization or biogenesis
                        is-acellular component organization
                                is-amembrane organization
                                        is-asingle-organism membrane organization
                                                is-aregulation of membrane lipid distribution
                                                        is-alipid translocation
                                                                is-aglycolipid translocation
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-alipid transport
                                                        is-alipid translocation
                                                                is-aglycolipid translocation
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-alipid transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-aorganic anion transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-aorganic substance transport
                                                is-aorganophosphate ester transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-aion transport
                                                        is-aanion transport
                                                                is-aorganic anion transport
                                                                        is-aphospholipid transport
                                                                                is-aaminophospholipid transport
                                                                                is-aceramide 1-phosphate transport
                                                                                is-alysophospholipid transport
                                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                                is-aphospholipid efflux +
                                                                                is-aphospholipid transfer to membrane
                                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                                        regulatesregulation of phospholipid translocation +
                                                                                is-aplatelet activating factor secretion +
                                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-alipid transport
                                                        is-alipid translocation
                                                                is-aglycolipid translocation
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-alipid transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-aestablishment of localization
                                is-atransport
                                        is-asingle-organism transport
                                                is-aorganophosphate ester transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-alipid localization
                                        part-oflipid transport
                                                is-alipid translocation
                                                        is-aglycolipid translocation
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-alipid localization
                                        part-oflipid transport
                                                is-aphospholipid transport
                                                        is-aaminophospholipid transport
                                                        is-aceramide 1-phosphate transport
                                                        is-alysophospholipid transport
                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                        is-aphospholipid efflux +
                                                        is-aphospholipid transfer to membrane
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +
                                                        is-aplatelet activating factor secretion +
                                                        positively-regulatespositive regulation of phospholipid transport +
                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-aion transport
                                                is-aanion transport
                                                        is-aorganic anion transport
                                                                is-aphospholipid transport
                                                                        is-aaminophospholipid transport
                                                                        is-aceramide 1-phosphate transport
                                                                        is-alysophospholipid transport
                                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                                        is-aphospholipid efflux +
                                                                        is-aphospholipid transfer to membrane
                                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                                regulatesregulation of phospholipid translocation +
                                                                        is-aplatelet activating factor secretion +
                                                                        positively-regulatespositive regulation of phospholipid transport +
                                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-alipid transport
                                                is-alipid translocation
                                                        is-aglycolipid translocation
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-alipid transport
                                                is-aphospholipid transport
                                                        is-aaminophospholipid transport
                                                        is-aceramide 1-phosphate transport
                                                        is-alysophospholipid transport
                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                        is-aphospholipid efflux +
                                                        is-aphospholipid transfer to membrane
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +
                                                        is-aplatelet activating factor secretion +
                                                        positively-regulatespositive regulation of phospholipid transport +
                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-aorganophosphate ester transport
                                                is-aphospholipid transport
                                                        is-aaminophospholipid transport
                                                        is-aceramide 1-phosphate transport
                                                        is-alysophospholipid transport
                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                        is-aphospholipid efflux +
                                                        is-aphospholipid transfer to membrane
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +
                                                        is-aplatelet activating factor secretion +
                                                        positively-regulatespositive regulation of phospholipid transport +
                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-aion transport
                                                is-aanion transport
                                                        is-aorganic anion transport
                                                                is-aphospholipid transport
                                                                        is-aaminophospholipid transport
                                                                        is-aceramide 1-phosphate transport
                                                                        is-alysophospholipid transport
                                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                                        is-aphospholipid efflux +
                                                                        is-aphospholipid transfer to membrane
                                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                                regulatesregulation of phospholipid translocation +
                                                                        is-aplatelet activating factor secretion +
                                                                        positively-regulatespositive regulation of phospholipid transport +
                                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-alipid transport
                                                is-alipid translocation
                                                        is-aglycolipid translocation
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-alipid transport
                                                is-aphospholipid transport
                                                        is-aaminophospholipid transport
                                                        is-aceramide 1-phosphate transport
                                                        is-alysophospholipid transport
                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                        is-aphospholipid efflux +
                                                        is-aphospholipid transfer to membrane
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +
                                                        is-aplatelet activating factor secretion +
                                                        positively-regulatespositive regulation of phospholipid transport +
                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-asingle-organism transport
                                        is-aorganophosphate ester transport
                                                is-aphospholipid transport
                                                        is-aaminophospholipid transport
                                                        is-aceramide 1-phosphate transport
                                                        is-alysophospholipid transport
                                                        negatively-regulatesnegative regulation of phospholipid transport +
                                                        is-aphospholipid efflux +
                                                        is-aphospholipid transfer to membrane
                                                        is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                negatively-regulatesnegative regulation of phospholipid translocation
                                                                positively-regulatespositive regulation of phospholipid translocation
                                                                regulatesregulation of phospholipid translocation +
                                                        is-aplatelet activating factor secretion +
                                                        positively-regulatespositive regulation of phospholipid transport +
                                                        regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism membrane organization
                                is-aregulation of membrane lipid distribution
                                        is-alipid translocation
                                                is-aglycolipid translocation
                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                        positively-regulatespositive regulation of phospholipid translocation
                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-aion transport
                                        is-aanion transport
                                                is-aorganic anion transport
                                                        is-aphospholipid transport
                                                                is-aaminophospholipid transport
                                                                is-aceramide 1-phosphate transport
                                                                is-alysophospholipid transport
                                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                                is-aphospholipid efflux +
                                                                is-aphospholipid transfer to membrane
                                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                                        positively-regulatespositive regulation of phospholipid translocation
                                                                        regulatesregulation of phospholipid translocation +
                                                                is-aplatelet activating factor secretion +
                                                                positively-regulatespositive regulation of phospholipid transport +
                                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-alipid transport
                                        is-alipid translocation
                                                is-aglycolipid translocation
                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                        positively-regulatespositive regulation of phospholipid translocation
                                                        regulatesregulation of phospholipid translocation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-alipid transport
                                        is-aphospholipid transport
                                                is-aaminophospholipid transport
                                                is-aceramide 1-phosphate transport
                                                is-alysophospholipid transport
                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                is-aphospholipid efflux +
                                                is-aphospholipid transfer to membrane
                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                        positively-regulatespositive regulation of phospholipid translocation
                                                        regulatesregulation of phospholipid translocation +
                                                is-aplatelet activating factor secretion +
                                                positively-regulatespositive regulation of phospholipid transport +
                                                regulatesregulation of phospholipid transport +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism transport
                                is-aorganophosphate ester transport
                                        is-aphospholipid transport
                                                is-aaminophospholipid transport
                                                is-aceramide 1-phosphate transport
                                                is-alysophospholipid transport
                                                negatively-regulatesnegative regulation of phospholipid transport +
                                                is-aphospholipid efflux +
                                                is-aphospholipid transfer to membrane
                                                is-aphospholipid translocation [GO:0045332] (20 genes, 23 annotations)
                                                        negatively-regulatesnegative regulation of phospholipid translocation
                                                        positively-regulatespositive regulation of phospholipid translocation
                                                        regulatesregulation of phospholipid translocation +
                                                is-aplatelet activating factor secretion +
                                                positively-regulatespositive regulation of phospholipid transport +
                                                regulatesregulation of phospholipid transport +


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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory