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Gene Ontology Browser
Term Detail
GO term:canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
Synonym: canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation
Synonym: canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation
Synonym: canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation
GO id:GO:0044338
Definition:The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.
Number of paths to term: 13

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-acanonical Wnt signaling pathway
                                                                        is-acanonical Wnt signaling pathway involved in heart development +
                                                                        is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                        is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                        is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                        is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                        is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                        is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                        is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                        negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                        positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                        part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                        regulatesregulation of canonical Wnt signaling pathway +
                                                                        is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-acanonical Wnt signaling pathway
                                                                        is-acanonical Wnt signaling pathway involved in heart development +
                                                                        is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                        is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                        is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                        is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                        is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                        is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                        is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                        negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                        positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                        part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                        regulatesregulation of canonical Wnt signaling pathway +
                                                                        is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-amesenchymal stem cell differentiation
                                                                is-aamniotic stem cell differentiation +
                                                                part-ofcanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-amesenchymal stem cell differentiation involved in nephron morphogenesis +
                                                                negatively-regulatesnegative regulation of mesenchymal stem cell differentiation +
                                                                positively-regulatespositive regulation of mesenchymal stem cell differentiation +
                                                                regulatesregulation of mesenchymal stem cell differentiation +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-amesenchymal stem cell differentiation
                                                                is-aamniotic stem cell differentiation +
                                                                part-ofcanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-amesenchymal stem cell differentiation involved in nephron morphogenesis +
                                                                negatively-regulatesnegative regulation of mesenchymal stem cell differentiation +
                                                                positively-regulatespositive regulation of mesenchymal stem cell differentiation +
                                                                regulatesregulation of mesenchymal stem cell differentiation +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aWnt signaling pathway
                                                        is-acanonical Wnt signaling pathway
                                                                is-acanonical Wnt signaling pathway involved in heart development +
                                                                is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                regulatesregulation of canonical Wnt signaling pathway +
                                                                is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aWnt signaling pathway
                                                                is-acanonical Wnt signaling pathway
                                                                        is-acanonical Wnt signaling pathway involved in heart development +
                                                                        is-acanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                        is-acanonical Wnt signaling pathway involved in mesonephros development +
                                                                        is-acanonical Wnt signaling pathway involved in metanephric kidney development +
                                                                        is-acanonical Wnt signaling pathway involved in negative regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in neural crest cell differentiation +
                                                                        is-acanonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +
                                                                        is-acanonical Wnt signaling pathway involved in osteoblast differentiation
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of apoptotic process
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of endothelial cell migration
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
                                                                        is-acanonical Wnt signaling pathway involved in positive regulation of wound healing
                                                                        is-acanonical Wnt signaling pathway involved in regulation of cell proliferation +
                                                                        negatively-regulatesnegative regulation of canonical Wnt signaling pathway +
                                                                        positively-regulatespositive regulation of canonical Wnt signaling pathway +
                                                                        part-ofreceptor internalization involved in canonical Wnt signaling pathway
                                                                        regulatesregulation of canonical Wnt signaling pathway +
                                                                        is-aregulation of hair cycle by canonical Wnt signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-amesenchymal stem cell differentiation
                                                                is-aamniotic stem cell differentiation +
                                                                part-ofcanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-amesenchymal stem cell differentiation involved in nephron morphogenesis +
                                                                negatively-regulatesnegative regulation of mesenchymal stem cell differentiation +
                                                                positively-regulatespositive regulation of mesenchymal stem cell differentiation +
                                                                regulatesregulation of mesenchymal stem cell differentiation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-amesenchymal stem cell differentiation
                                                                is-aamniotic stem cell differentiation +
                                                                part-ofcanonical Wnt signaling pathway involved in mesenchymal stem cell differentiation [GO:0044338] (2 genes, 2 annotations)
                                                                is-amesenchymal stem cell differentiation involved in nephron morphogenesis +
                                                                negatively-regulatesnegative regulation of mesenchymal stem cell differentiation +
                                                                positively-regulatespositive regulation of mesenchymal stem cell differentiation +
                                                                regulatesregulation of mesenchymal stem cell differentiation +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory