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Gene Ontology Browser
Term Detail
GO term:multicellular organismal protein catabolic process
Synonym: organismal protein breakdown
Synonym: organismal protein catabolism
Synonym: organismal protein degradation
GO id:GO:0044254
Definition:The chemical reactions and pathways resulting in the breakdown of a protein in a multicellular organism, occurring at the tissue, organ, or organismal level.
Number of paths to term: 24

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-amulticellular organismal macromolecule catabolic process
                                                        is-amulticellular organismal carbohydrate catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acatabolism by organism of protein in other organism involved in symbiotic interaction +
                                                        is-acellular protein catabolic process +
                                                        is-aglycoprotein catabolic process +
                                                        is-ahemoglobin catabolic process
                                                        is-ainsulin catabolic process
                                                        is-alipoprotein catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin
                                                        negatively-regulatesnegative regulation of protein catabolic process +
                                                        positively-regulatespositive regulation of protein catabolic process +
                                                        is-aproteasomal protein catabolic process +
                                                        regulatesregulation of protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acatabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-ametaphase/anaphase transition of mitotic cell cycle +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                is-aangiotensin catabolic process in blood
                                                is-aprotein catabolic process by pepsin
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-amulticellular organismal macromolecule catabolic process
                                                        is-amulticellular organismal carbohydrate catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acatabolism by organism of protein in other organism involved in symbiotic interaction +
                                                        is-acellular protein catabolic process +
                                                        is-aglycoprotein catabolic process +
                                                        is-ahemoglobin catabolic process
                                                        is-ainsulin catabolic process
                                                        is-alipoprotein catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin
                                                        negatively-regulatesnegative regulation of protein catabolic process +
                                                        positively-regulatespositive regulation of protein catabolic process +
                                                        is-aproteasomal protein catabolic process +
                                                        regulatesregulation of protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein catabolic process
                                                        is-acatabolism by organism of protein in other organism involved in symbiotic interaction +
                                                        is-acellular protein catabolic process +
                                                        is-aglycoprotein catabolic process +
                                                        is-ahemoglobin catabolic process
                                                        is-ainsulin catabolic process
                                                        is-alipoprotein catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin
                                                        negatively-regulatesnegative regulation of protein catabolic process +
                                                        positively-regulatespositive regulation of protein catabolic process +
                                                        is-aproteasomal protein catabolic process +
                                                        regulatesregulation of protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-amulticellular organismal macromolecule catabolic process
                                                        is-amulticellular organismal carbohydrate catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic substance catabolic process
                                        is-amacromolecule catabolic process
                                                is-aprotein catabolic process
                                                        is-acatabolism by organism of protein in other organism involved in symbiotic interaction +
                                                        is-acellular protein catabolic process +
                                                        is-aglycoprotein catabolic process +
                                                        is-ahemoglobin catabolic process
                                                        is-ainsulin catabolic process
                                                        is-alipoprotein catabolic process +
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin
                                                        negatively-regulatesnegative regulation of protein catabolic process +
                                                        positively-regulatespositive regulation of protein catabolic process +
                                                        is-aproteasomal protein catabolic process +
                                                        regulatesregulation of protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-amulticellular organismal protein metabolic process
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein catabolic process
                                                is-acatabolism by organism of protein in other organism involved in symbiotic interaction +
                                                is-acellular protein catabolic process +
                                                is-aglycoprotein catabolic process +
                                                is-ahemoglobin catabolic process
                                                is-ainsulin catabolic process
                                                is-alipoprotein catabolic process +
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin
                                                negatively-regulatesnegative regulation of protein catabolic process +
                                                positively-regulatespositive regulation of protein catabolic process +
                                                is-aproteasomal protein catabolic process +
                                                regulatesregulation of protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-ametaphase/anaphase transition of mitotic cell cycle +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                is-aangiotensin catabolic process in blood
                                                is-aprotein catabolic process by pepsin
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-adigestion
                                        is-aprotein digestion
                                                part-ofmulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-adigestion
                                        is-aprotein digestion
                                                part-ofmulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal catabolic process
                                                is-acollagen catabolic process +
                                                is-amulticellular organismal carbohydrate catabolic process +
                                                is-amulticellular organismal lipid catabolic process +
                                                is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                        is-aangiotensin catabolic process in blood
                                                        is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-amulticellular organismal metabolic process
                                        is-amulticellular organismal macromolecule metabolic process
                                                is-amulticellular organismal protein metabolic process
                                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                                is-aangiotensin catabolic process in blood
                                                                is-aprotein catabolic process by pepsin


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asingle-organism catabolic process
                                        is-a2,5-dihydroxypyridine catabolic process to fumarate
                                        is-a2-aminobenzenesulfonate catabolic process
                                        is-aacetyl-CoA assimilation pathway
                                        is-aacetylcholine catabolic process +
                                        is-aaldehyde catabolic process +
                                        is-aalkane catabolic process +
                                        is-aalkanesulfonate catabolic process
                                        is-aalkyne catabolic process +
                                        is-aatrazine catabolic process to urea
                                        is-aaustinol catabolic process
                                        is-aautophagy in response to ER overload
                                        is-acell septum edging catabolic process
                                        is-acellular lactam catabolic process +
                                        is-achondroitin sulfate catabolic process
                                        is-acollagen catabolic process +
                                        is-acyanate catabolic process
                                        is-acyanide catabolic process
                                        is-acytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
                                        is-adeoxyhypusine biosynthetic process from spermidine
                                        is-adiacetylchitobiose catabolic process to glucosamine and acetate
                                        is-adibenzofuran catabolic process
                                        is-adimethylsilanediol catabolic process
                                        is-aER-associated misfolded protein catabolic process
                                        is-aether catabolic process +
                                        is-afatty acid derivative catabolic process +
                                        is-agalactosaminoglycan catabolic process
                                        is-aglutathione derivative catabolic process +
                                        is-aglycosyl compound catabolic process +
                                        is-ahalogenated hydrocarbon catabolic process +
                                        is-aheparan sulfate proteoglycan catabolic process
                                        is-aheparin catabolic process
                                        is-ahyaluronan catabolic process
                                        is-ahydrogen peroxide catabolic process +
                                        is-akeratan sulfate catabolic process
                                        is-alipid catabolic process +
                                        is-amacroautophagy +
                                        is-ameiotic DNA double-strand break processing +
                                        is-ametaphase/anaphase transition of mitotic cell cycle +
                                        is-amicroautophagy +
                                        is-amulticellular organismal protein catabolic process [GO:0044254] (1 genes, 1 annotations)
                                                is-aangiotensin catabolic process in blood
                                                is-aprotein catabolic process by pepsin
                                        is-anitrate catabolic process
                                        is-anucleobase catabolic process +
                                        is-anucleoside phosphate catabolic process +
                                        is-anucleus-associated proteasomal ubiquitin-dependent protein catabolic process +
                                        is-aoctamethylcyclotetrasiloxane catabolic process to dimethylsilanediol
                                        is-aperoxisome degradation +
                                        is-aphenylpropanoid catabolic process +
                                        is-apheromone catabolic process
                                        is-apigment catabolic process +
                                        is-apolyphosphate catabolic process
                                        is-aquercetin catabolic process
                                        is-asecondary metabolite catabolic process +
                                        is-asingle-organism carbohydrate catabolic process +
                                        is-asmall molecule catabolic process +
                                        is-atartrate catabolic process


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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory