| GO term: | positive regulation of tumor necrosis factor biosynthetic process |
| Synonym: | activation of tumor necrosis factor biosynthetic process |
| Synonym: | positive regulation of TNF alpha biosynthesis |
| Synonym: | positive regulation of TNF-alpha biosynthesis |
| Synonym: | positive regulation of TNF alpha biosynthetic process |
| Synonym: | positive regulation of TNF-alpha biosynthetic process |
| Synonym: | positive regulation of TNF biosynthesis |
| Synonym: | positive regulation of TNF biosynthetic process |
| Synonym: | positive regulation of tumor necrosis factor-alpha biosynthesis |
| Synonym: | positive regulation of tumor necrosis factor-alpha biosynthetic process |
| Synonym: | positive regulation of tumor necrosis factor anabolism |
| Synonym: | positive regulation of tumor necrosis factor biosynthesis |
| Synonym: | positive regulation of tumor necrosis factor formation |
| Synonym: | positive regulation of tumor necrosis factor synthesis |
| Synonym: | stimulation of tumor necrosis factor biosynthetic process |
| Synonym: | up regulation of tumor necrosis factor biosynthetic process |
| Synonym: | up-regulation of tumor necrosis factor biosynthetic process |
| Synonym: | upregulation of tumor necrosis factor biosynthetic process |
| GO id: | GO:0042535 |
| Definition: | Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. |
| Comments | Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). |
| Number of paths to term: | 226 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship