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Gene Ontology Browser
Term Detail
GO term:response to chemical
Synonym: response to chemical stimulus
Synonym: response to chemical substance
GO id:GO:0042221
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
CommentsNote that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-abehavior +
                        is-acellular response to stimulus +
                        is-adetection of stimulus +
                        is-aimmune response +
                        is-amuscle adaptation +
                        negatively-regulatesnegative regulation of response to stimulus +
                        positively-regulatespositive regulation of response to stimulus +
                        is-aprotein activation cascade +
                        regulatesregulation of response to stimulus +
                        is-aresponse to abiotic stimulus +
                        is-aresponse to activity +
                        is-aresponse to biotic stimulus +
                        is-aresponse to chemical [GO:0042221] (3698 genes, 6469 annotations)
                                is-acellular response to chemical stimulus +
                                is-achemosensory behavior +
                                is-achemotaxis +
                                is-achemotropism
                                is-adetection of chemical stimulus +
                                is-afilamentous growth of a population of unicellular organisms in response to chemical stimulus +
                                is-anegative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus
                                is-aregulation of synaptic plasticity by chemical substance +
                                is-aresponse to acid +
                                is-aresponse to antimetabolite
                                is-aresponse to aromatase inhibitor
                                is-aresponse to arsenic-containing substance +
                                is-aresponse to asparaginase
                                is-aresponse to boron-containing substance +
                                is-aresponse to docetaxel trihydrate
                                is-aresponse to drug +
                                is-aresponse to food +
                                is-aresponse to inorganic substance +
                                is-aresponse to irinotecan
                                is-aresponse to nitrogen compound +
                                is-aresponse to nutrient +
                                is-aresponse to organic substance +
                                is-aresponse to oxygen-containing compound +
                                is-aresponse to reverse transcriptase inhibitor
                                is-aresponse to salt +
                                is-aresponse to tacrolimus +
                                is-aresponse to TNF agonist
                                is-aresponse to topoisomerase inhibitor +
                                is-aresponse to toxic substance +
                                is-aresponse to transition metal nanoparticle +
                                is-aresponse to xenobiotic stimulus +
                                is-asalt aversion
                        is-aresponse to dietary excess +
                        is-aresponse to endogenous stimulus +
                        is-aresponse to external stimulus +
                        is-aresponse to inactivity +
                        is-aresponse to redox state +
                        is-aresponse to stimulus involved in regulation of muscle adaptation +
                        is-aresponse to stress +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory