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Gene Ontology Browser
Term Detail
GO term:somatostatin signaling pathway
Synonym: somatostatin-activated somatostatin receptor signaling pathway
Synonym: somatostatin-mediated signaling pathway
Synonym: somatostatin signalling pathway
Synonym: somatotrophin release inhibiting factor signaling pathway
Synonym: SRIF signaling pathway
Synonym: SST signaling pathway
GO id:GO:0038170
Definition:The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.
Number of paths to term: 25

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-asomatostatin receptor signaling pathway
                                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-ahormone-mediated signaling pathway
                                                        is-aabscisic acid-activated signaling pathway +
                                                        is-aadiponectin-activated signaling pathway
                                                        is-aauxin-activated signaling pathway +
                                                        is-acytokinin-activated signaling pathway +
                                                        is-aethylene-activated signaling pathway +
                                                        is-agibberellin mediated signaling pathway +
                                                        is-ahormone-mediated apoptotic signaling pathway
                                                        is-ajasmonic acid mediated signaling pathway +
                                                        is-ajuvenile hormone mediated signaling pathway
                                                        is-aprolactin signaling pathway +
                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                        is-asteroid hormone mediated signaling pathway +
                                                        is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-ahormone-mediated signaling pathway
                                                                is-aabscisic acid-activated signaling pathway +
                                                                is-aadiponectin-activated signaling pathway
                                                                is-aauxin-activated signaling pathway +
                                                                is-acytokinin-activated signaling pathway +
                                                                is-aethylene-activated signaling pathway +
                                                                is-agibberellin mediated signaling pathway +
                                                                is-ahormone-mediated apoptotic signaling pathway
                                                                is-ajasmonic acid mediated signaling pathway +
                                                                is-ajuvenile hormone mediated signaling pathway
                                                                is-aprolactin signaling pathway +
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                                is-asteroid hormone mediated signaling pathway +
                                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-asomatostatin receptor signaling pathway
                                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-ahormone-mediated signaling pathway
                                                        is-aabscisic acid-activated signaling pathway +
                                                        is-aadiponectin-activated signaling pathway
                                                        is-aauxin-activated signaling pathway +
                                                        is-acytokinin-activated signaling pathway +
                                                        is-aethylene-activated signaling pathway +
                                                        is-agibberellin mediated signaling pathway +
                                                        is-ahormone-mediated apoptotic signaling pathway
                                                        is-ajasmonic acid mediated signaling pathway +
                                                        is-ajuvenile hormone mediated signaling pathway
                                                        is-aprolactin signaling pathway +
                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                        is-asteroid hormone mediated signaling pathway +
                                                        is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-ahormone-mediated signaling pathway
                                                                is-aabscisic acid-activated signaling pathway +
                                                                is-aadiponectin-activated signaling pathway
                                                                is-aauxin-activated signaling pathway +
                                                                is-acytokinin-activated signaling pathway +
                                                                is-aethylene-activated signaling pathway +
                                                                is-agibberellin mediated signaling pathway +
                                                                is-ahormone-mediated apoptotic signaling pathway
                                                                is-ajasmonic acid mediated signaling pathway +
                                                                is-ajuvenile hormone mediated signaling pathway
                                                                is-aprolactin signaling pathway +
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                                is-asteroid hormone mediated signaling pathway +
                                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-ahormone-mediated signaling pathway
                                                                is-aabscisic acid-activated signaling pathway +
                                                                is-aadiponectin-activated signaling pathway
                                                                is-aauxin-activated signaling pathway +
                                                                is-acytokinin-activated signaling pathway +
                                                                is-aethylene-activated signaling pathway +
                                                                is-agibberellin mediated signaling pathway +
                                                                is-ahormone-mediated apoptotic signaling pathway
                                                                is-ajasmonic acid mediated signaling pathway +
                                                                is-ajuvenile hormone mediated signaling pathway
                                                                is-aprolactin signaling pathway +
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                                is-asteroid hormone mediated signaling pathway +
                                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-ahormone-mediated signaling pathway
                                                                is-aabscisic acid-activated signaling pathway +
                                                                is-aadiponectin-activated signaling pathway
                                                                is-aauxin-activated signaling pathway +
                                                                is-acytokinin-activated signaling pathway +
                                                                is-aethylene-activated signaling pathway +
                                                                is-agibberellin mediated signaling pathway +
                                                                is-ahormone-mediated apoptotic signaling pathway
                                                                is-ajasmonic acid mediated signaling pathway +
                                                                is-ajuvenile hormone mediated signaling pathway
                                                                is-aprolactin signaling pathway +
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                                is-asteroid hormone mediated signaling pathway +
                                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to hormone
                                                is-acellular response to hormone stimulus
                                                        is-ahormone-mediated signaling pathway
                                                                is-aabscisic acid-activated signaling pathway +
                                                                is-aadiponectin-activated signaling pathway
                                                                is-aauxin-activated signaling pathway +
                                                                is-acytokinin-activated signaling pathway +
                                                                is-aethylene-activated signaling pathway +
                                                                is-agibberellin mediated signaling pathway +
                                                                is-ahormone-mediated apoptotic signaling pathway
                                                                is-ajasmonic acid mediated signaling pathway +
                                                                is-ajuvenile hormone mediated signaling pathway
                                                                is-aprolactin signaling pathway +
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                                is-asteroid hormone mediated signaling pathway +
                                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-acellular response to endogenous stimulus
                                        is-acellular response to hormone stimulus
                                                is-ahormone-mediated signaling pathway
                                                        is-aabscisic acid-activated signaling pathway +
                                                        is-aadiponectin-activated signaling pathway
                                                        is-aauxin-activated signaling pathway +
                                                        is-acytokinin-activated signaling pathway +
                                                        is-aethylene-activated signaling pathway +
                                                        is-agibberellin mediated signaling pathway +
                                                        is-ahormone-mediated apoptotic signaling pathway
                                                        is-ajasmonic acid mediated signaling pathway +
                                                        is-ajuvenile hormone mediated signaling pathway
                                                        is-aprolactin signaling pathway +
                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                        is-asteroid hormone mediated signaling pathway +
                                                        is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to hormone
                                        is-acellular response to hormone stimulus
                                                is-ahormone-mediated signaling pathway
                                                        is-aabscisic acid-activated signaling pathway +
                                                        is-aadiponectin-activated signaling pathway
                                                        is-aauxin-activated signaling pathway +
                                                        is-acytokinin-activated signaling pathway +
                                                        is-aethylene-activated signaling pathway +
                                                        is-agibberellin mediated signaling pathway +
                                                        is-ahormone-mediated apoptotic signaling pathway
                                                        is-ajasmonic acid mediated signaling pathway +
                                                        is-ajuvenile hormone mediated signaling pathway
                                                        is-aprolactin signaling pathway +
                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                        is-asteroid hormone mediated signaling pathway +
                                                        is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-asomatostatin receptor signaling pathway
                                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-ahormone-mediated signaling pathway
                                                is-aabscisic acid-activated signaling pathway +
                                                is-aadiponectin-activated signaling pathway
                                                is-aauxin-activated signaling pathway +
                                                is-acytokinin-activated signaling pathway +
                                                is-aethylene-activated signaling pathway +
                                                is-agibberellin mediated signaling pathway +
                                                is-ahormone-mediated apoptotic signaling pathway
                                                is-ajasmonic acid mediated signaling pathway +
                                                is-ajuvenile hormone mediated signaling pathway
                                                is-aprolactin signaling pathway +
                                                is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                is-asteroid hormone mediated signaling pathway +
                                                is-athyroid hormone mediated signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-asomatostatin receptor signaling pathway
                                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-ahormone-mediated signaling pathway
                                                        is-aabscisic acid-activated signaling pathway +
                                                        is-aadiponectin-activated signaling pathway
                                                        is-aauxin-activated signaling pathway +
                                                        is-acytokinin-activated signaling pathway +
                                                        is-aethylene-activated signaling pathway +
                                                        is-agibberellin mediated signaling pathway +
                                                        is-ahormone-mediated apoptotic signaling pathway
                                                        is-ajasmonic acid mediated signaling pathway +
                                                        is-ajuvenile hormone mediated signaling pathway
                                                        is-aprolactin signaling pathway +
                                                        is-asomatostatin signaling pathway [GO:0038170] (4 genes, 6 annotations)
                                                        is-asteroid hormone mediated signaling pathway +
                                                        is-athyroid hormone mediated signaling pathway +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory