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Gene Ontology Browser
Term Detail
GO term:insulin receptor signaling pathway via phosphatidylinositol 3-kinase
Synonym: insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade
Synonym: insulin receptor signaling pathway via PI3K cascade
Synonym: insulin receptor signaling via PI3K
Synonym: insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade
GO id:GO:0038028
Definition:The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.
Number of paths to term: 48

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to nitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxygen-containing compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to nitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxygen-containing compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to nitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to organic substance
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-acellular response to chemical stimulus
                                        is-acellular response to oxygen-containing compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to nitrogen compound
                                        is-acellular response to nitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to nitrogen compound
                                        is-aresponse to organonitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to nitrogen compound
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to nitrogen compound
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-aresponse to peptide hormone
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to nitrogen compound
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-aresponse to peptide hormone
                                                                is-aresponse to insulin
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-acellular response to organic substance
                                                is-acellular response to hormone stimulus
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-acellular response to organic substance
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to hormone
                                                is-acellular response to hormone stimulus
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to hormone
                                                is-aresponse to peptide hormone
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to hormone
                                                is-aresponse to peptide hormone
                                                        is-aresponse to insulin
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to organonitrogen compound
                                                is-acellular response to organonitrogen compound
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-acellular response to peptide
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-aresponse to peptide hormone
                                                                is-acellular response to peptide hormone stimulus
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to organic substance
                                        is-aresponse to organonitrogen compound
                                                is-aresponse to peptide
                                                        is-aresponse to peptide hormone
                                                                is-aresponse to insulin
                                                                        is-acellular response to insulin stimulus
                                                                                is-ainsulin receptor signaling pathway
                                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to oxygen-containing compound
                                        is-acellular response to oxygen-containing compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to oxygen-containing compound
                                        is-aresponse to peptide
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to oxygen-containing compound
                                        is-aresponse to peptide
                                                is-aresponse to peptide hormone
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to chemical
                                is-aresponse to oxygen-containing compound
                                        is-aresponse to peptide
                                                is-aresponse to peptide hormone
                                                        is-aresponse to insulin
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-acellular response to endogenous stimulus
                                        is-acellular response to hormone stimulus
                                                is-acellular response to peptide hormone stimulus
                                                        is-acellular response to insulin stimulus
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-acellular response to endogenous stimulus
                                        is-acellular response to organonitrogen compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to hormone
                                        is-acellular response to hormone stimulus
                                                is-acellular response to peptide hormone stimulus
                                                        is-acellular response to insulin stimulus
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to hormone
                                        is-aresponse to peptide hormone
                                                is-acellular response to peptide hormone stimulus
                                                        is-acellular response to insulin stimulus
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to hormone
                                        is-aresponse to peptide hormone
                                                is-aresponse to insulin
                                                        is-acellular response to insulin stimulus
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to organonitrogen compound
                                        is-acellular response to organonitrogen compound
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to organonitrogen compound
                                        is-aresponse to peptide
                                                is-acellular response to peptide
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to organonitrogen compound
                                        is-aresponse to peptide
                                                is-aresponse to peptide hormone
                                                        is-acellular response to peptide hormone stimulus
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to endogenous stimulus
                                is-aresponse to organonitrogen compound
                                        is-aresponse to peptide
                                                is-aresponse to peptide hormone
                                                        is-aresponse to insulin
                                                                is-acellular response to insulin stimulus
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                is-ainsulin receptor signaling pathway
                                                                        is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                        is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                        is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                        negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                        positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                        regulatesregulation of insulin receptor signaling pathway +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway
                                                                        is-ainsulin receptor signaling pathway
                                                                                is-ainsulin receptor signaling pathway involved in dauer larval development
                                                                                is-ainsulin receptor signaling pathway involved in determination of adult lifespan +
                                                                                is-ainsulin receptor signaling pathway via phosphatidylinositol 3-kinase [GO:0038028] (3 genes, 3 annotations)
                                                                                negatively-regulatesnegative regulation of insulin receptor signaling pathway +
                                                                                positively-regulatespositive regulation of insulin receptor signaling pathway +
                                                                                regulatesregulation of insulin receptor signaling pathway +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory