| GO term: | senescence-associated heterochromatin focus |
| Synonym: | SAHF |
| Synonym: | senescence-associated heterochromatin foci |
| GO id: | GO:0035985 |
| Definition: | A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes. |
| Number of paths to term: | 17 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcellcell partintracellularintracellular partintracellular organelleintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcellcell partintracellularintracellular partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcellcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcellcell partintracellular partintracellular organelleintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcellcell partintracellular partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellularintracellular partintracellular organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellularintracellular partintracellular organelleintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellularintracellular partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellular partintracellular organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellular partintracellular organelleintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentcell partintracellular partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentorganelleintracellular organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentorganelleintracellular organelleintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentorganellenon-membrane-bounded organelleintracellular non-membrane-bounded organellechromosomechromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentorganelleorganelle partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +cellular_componentorganelle partintracellular organelle partchromosomal partchromatinheterochromatincentromeric heterochromatin +HULC complexmating-type region heterochromatinnuclear heterochromatin +rDNA heterochromatinsenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)telomeric heterochromatin +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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