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Gene Ontology Browser
Term Detail
GO term:senescence-associated heterochromatin focus
Synonym: SAHF
Synonym: senescence-associated heterochromatin foci
GO id:GO:0035985
Definition:A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
Number of paths to term: 18

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular non-membrane-bounded organelle
                                                                is-achromosome
                                                                        part-ofchromosomal part
                                                                                is-achromatin
                                                                                        is-aheterochromatin
                                                                                                part-ofHULC complex
                                                                                                is-amating-type region heterochromatin
                                                                                                is-anuclear heterochromatin +
                                                                                                is-apericentric heterochromatin +
                                                                                                is-arDNA heterochromatin +
                                                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                                is-asubtelomeric heterochromatin
                                                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        part-ofintracellular organelle part
                                                                is-achromosomal part
                                                                        is-achromatin
                                                                                is-aheterochromatin
                                                                                        part-ofHULC complex
                                                                                        is-amating-type region heterochromatin
                                                                                        is-anuclear heterochromatin +
                                                                                        is-apericentric heterochromatin +
                                                                                        is-arDNA heterochromatin +
                                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                        is-asubtelomeric heterochromatin
                                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle part
                                                        is-achromosomal part
                                                                is-achromatin
                                                                        is-aheterochromatin
                                                                                part-ofHULC complex
                                                                                is-amating-type region heterochromatin
                                                                                is-anuclear heterochromatin +
                                                                                is-apericentric heterochromatin +
                                                                                is-arDNA heterochromatin +
                                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                is-asubtelomeric heterochromatin
                                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-achromosome
                                                                part-ofchromosomal part
                                                                        is-achromatin
                                                                                is-aheterochromatin
                                                                                        part-ofHULC complex
                                                                                        is-amating-type region heterochromatin
                                                                                        is-anuclear heterochromatin +
                                                                                        is-apericentric heterochromatin +
                                                                                        is-arDNA heterochromatin +
                                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                        is-asubtelomeric heterochromatin
                                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-achromosomal part
                                                                is-achromatin
                                                                        is-aheterochromatin
                                                                                part-ofHULC complex
                                                                                is-amating-type region heterochromatin
                                                                                is-anuclear heterochromatin +
                                                                                is-apericentric heterochromatin +
                                                                                is-arDNA heterochromatin +
                                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                is-asubtelomeric heterochromatin
                                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle part
                                                is-achromosomal part
                                                        is-achromatin
                                                                is-aheterochromatin
                                                                        part-ofHULC complex
                                                                        is-amating-type region heterochromatin
                                                                        is-anuclear heterochromatin +
                                                                        is-apericentric heterochromatin +
                                                                        is-arDNA heterochromatin +
                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                        is-asubtelomeric heterochromatin
                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-achromosome
                                                                part-ofchromosomal part
                                                                        is-achromatin
                                                                                is-aheterochromatin
                                                                                        part-ofHULC complex
                                                                                        is-amating-type region heterochromatin
                                                                                        is-anuclear heterochromatin +
                                                                                        is-apericentric heterochromatin +
                                                                                        is-arDNA heterochromatin +
                                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                        is-asubtelomeric heterochromatin
                                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-achromosomal part
                                                                is-achromatin
                                                                        is-aheterochromatin
                                                                                part-ofHULC complex
                                                                                is-amating-type region heterochromatin
                                                                                is-anuclear heterochromatin +
                                                                                is-apericentric heterochromatin +
                                                                                is-arDNA heterochromatin +
                                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                is-asubtelomeric heterochromatin
                                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle part
                                                is-achromosomal part
                                                        is-achromatin
                                                                is-aheterochromatin
                                                                        part-ofHULC complex
                                                                        is-amating-type region heterochromatin
                                                                        is-anuclear heterochromatin +
                                                                        is-apericentric heterochromatin +
                                                                        is-arDNA heterochromatin +
                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                        is-asubtelomeric heterochromatin
                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular non-membrane-bounded organelle
                                                is-achromosome
                                                        part-ofchromosomal part
                                                                is-achromatin
                                                                        is-aheterochromatin
                                                                                part-ofHULC complex
                                                                                is-amating-type region heterochromatin
                                                                                is-anuclear heterochromatin +
                                                                                is-apericentric heterochromatin +
                                                                                is-arDNA heterochromatin +
                                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                                is-asubtelomeric heterochromatin
                                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        part-ofintracellular organelle part
                                                is-achromosomal part
                                                        is-achromatin
                                                                is-aheterochromatin
                                                                        part-ofHULC complex
                                                                        is-amating-type region heterochromatin
                                                                        is-anuclear heterochromatin +
                                                                        is-apericentric heterochromatin +
                                                                        is-arDNA heterochromatin +
                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                        is-asubtelomeric heterochromatin
                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle part
                                        is-achromosomal part
                                                is-achromatin
                                                        is-aheterochromatin
                                                                part-ofHULC complex
                                                                is-amating-type region heterochromatin
                                                                is-anuclear heterochromatin +
                                                                is-apericentric heterochromatin +
                                                                is-arDNA heterochromatin +
                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                is-asubtelomeric heterochromatin
                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-achromatin
                                is-aheterochromatin
                                        part-ofHULC complex
                                        is-amating-type region heterochromatin
                                        is-anuclear heterochromatin +
                                        is-apericentric heterochromatin +
                                        is-arDNA heterochromatin +
                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                        is-asubtelomeric heterochromatin
                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-achromosome
                                                part-ofchromosomal part
                                                        is-achromatin
                                                                is-aheterochromatin
                                                                        part-ofHULC complex
                                                                        is-amating-type region heterochromatin
                                                                        is-anuclear heterochromatin +
                                                                        is-apericentric heterochromatin +
                                                                        is-arDNA heterochromatin +
                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                        is-asubtelomeric heterochromatin
                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                part-ofintracellular organelle part
                                        is-achromosomal part
                                                is-achromatin
                                                        is-aheterochromatin
                                                                part-ofHULC complex
                                                                is-amating-type region heterochromatin
                                                                is-anuclear heterochromatin +
                                                                is-apericentric heterochromatin +
                                                                is-arDNA heterochromatin +
                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                is-asubtelomeric heterochromatin
                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-anon-membrane-bounded organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-achromosome
                                                part-ofchromosomal part
                                                        is-achromatin
                                                                is-aheterochromatin
                                                                        part-ofHULC complex
                                                                        is-amating-type region heterochromatin
                                                                        is-anuclear heterochromatin +
                                                                        is-apericentric heterochromatin +
                                                                        is-arDNA heterochromatin +
                                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                        is-asubtelomeric heterochromatin
                                                                        is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        part-oforganelle part
                                is-aintracellular organelle part
                                        is-achromosomal part
                                                is-achromatin
                                                        is-aheterochromatin
                                                                part-ofHULC complex
                                                                is-amating-type region heterochromatin
                                                                is-anuclear heterochromatin +
                                                                is-apericentric heterochromatin +
                                                                is-arDNA heterochromatin +
                                                                is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                                is-asubtelomeric heterochromatin
                                                                is-atelomeric heterochromatin +


Gene_Ontology
        is-acellular_component
                is-aorganelle part
                        is-aintracellular organelle part
                                is-achromosomal part
                                        is-achromatin
                                                is-aheterochromatin
                                                        part-ofHULC complex
                                                        is-amating-type region heterochromatin
                                                        is-anuclear heterochromatin +
                                                        is-apericentric heterochromatin +
                                                        is-arDNA heterochromatin +
                                                        is-asenescence-associated heterochromatin focus [GO:0035985] (3 genes, 3 annotations)
                                                        is-asubtelomeric heterochromatin
                                                        is-atelomeric heterochromatin +


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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory