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Gene Ontology Browser
Term Detail
GO term:TORC1 complex
Synonym: dTORC1
Synonym: dTOR/dRaptor complex
Synonym: mTORC1
Synonym: nutrient sensitive complex
Synonym: rapamycin and nutrient-sensitive TOR complex
Synonym: TORC1
Synonym: TORC 1 complex
Synonym: TOR complex 1
GO id:GO:0031931
Definition:A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aTOR complex
                                                        is-aTORC1 complex [GO:0031931] (7 genes, 7 annotations)
                                                        is-aTORC2 complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aTOR complex
                                                is-aTORC1 complex [GO:0031931] (7 genes, 7 annotations)
                                                is-aTORC2 complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aTOR complex
                                                is-aTORC1 complex [GO:0031931] (7 genes, 7 annotations)
                                                is-aTORC2 complex


obsolete Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aTOR complex
                                        is-aTORC1 complex [GO:0031931] (7 genes, 7 annotations)
                                        is-aTORC2 complex


obsolete Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aprotein complex
                                is-a3M complex
                                is-aABIN2-NFKB1-MAP3K8 complex
                                is-aacetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex
                                is-aactin filament +
                                is-aactivated SUMO-E1 ligase complex
                                is-aactivin complex +
                                is-aacyl-CoA ceramide synthase complex
                                is-aADPG pyrophosphorylase complex +
                                is-aAIP1-IRE1 complex
                                is-aaminoacyl-tRNA synthetase multienzyme complex
                                is-aaminodeoxychorismate synthase complex
                                is-aanaerobic ribonucleoside-triphosphate reductase complex
                                is-aangiogenin-PRI complex
                                is-aAnxA2-p11 complex
                                is-aAPC-IQGAP complex
                                is-aAPC-IQGAP1-Cdc42 complex
                                is-aAPC-IQGAP1-CLIP-170 complex
                                is-aAPC-IQGAP1-Rac1 complex
                                is-aAPC-tubulin-IQGAP1 complex
                                is-aapolipoprotein B mRNA editing enzyme complex
                                is-aapoptosome
                                is-aArp2/3 protein complex
                                is-aASAP complex
                                is-aaster +
                                is-aASTRA complex
                                is-aAtg12-Atg5-Atg16 complex
                                is-aATPase inhibitor complex +
                                is-aATR-ATRIP complex
                                is-aaxonemal heterotrimeric kinesin-II complex
                                is-aB800-820 antenna complex
                                is-aB800-850 antenna complex
                                is-aB875 antenna complex
                                is-aBBSome
                                is-aBcl-2 family protein complex +
                                is-aBcl3-Bcl10 complex
                                is-abeta-catenin destruction complex
                                is-aBID-BCL-xl complex
                                is-aBLOC complex +
                                is-aBRCA1-A complex
                                is-aBRCA1-B complex
                                is-aBRCA1-C complex
                                is-aBRCA1-Rad51 complex
                                is-aBRCA2-BRAF35 complex
                                is-aBRCA2-MAGE-D1 complex
                                is-aBRISC complex
                                is-abub1-bub3 complex
                                is-abursicon neuropeptide hormone complex
                                is-aCAF-1 complex
                                is-aCAK-ERCC2 complex
                                is-acalcium- and calmodulin-dependent protein kinase complex
                                is-acalprotectin complex
                                is-acatalytic complex +
                                is-acatenin-TCF7L2 complex +
                                is-aCbf1-Met4-Met28 complex
                                is-aCBF3 complex
                                is-aCBM complex
                                is-aCbp3p-Cbp6 complex
                                is-aCCR4-NOT complex +
                                is-aCCR4-NOT core complex
                                is-aCD20-Lck-Fyn complex
                                is-aCD20-Lck-Lyn-Fyn complex
                                is-aCdc42 GTPase complex
                                is-aCdc50p-Drs2p complex
                                is-acell envelope Sec protein transport complex
                                is-aCENP-A recruiting complex
                                is-acentralspindlin complex
                                is-achaperonin ATPase complex +
                                is-achaperonin-containing T-complex
                                is-acheckpoint clamp complex
                                is-aCHOP-ATF3 complex
                                is-achromatin silencing complex +
                                is-aCIA complex
                                is-aciliary transition fiber
                                is-acitrate lyase complex
                                is-aclassical-complement-pathway C3/C5 convertase complex
                                is-aCNTFR-CLCF1 complex
                                is-aCoA-synthesizing protein complex
                                is-acohesin complex +
                                is-acohesin core heterodimer
                                is-acollagen trimer +
                                is-aCOMA complex
                                is-acomplement component C1 complex
                                is-acomplex of collagen trimers +
                                is-acondensed chromosome inner kinetochore +
                                is-acondensed chromosome outer kinetochore +
                                is-acondensin core heterodimer
                                is-aCOP9 signalosome
                                is-acore TFIIH complex +
                                is-aCORVET complex
                                is-aCRD-mediated mRNA stability complex
                                is-aCRLF-CLCF1 complex
                                is-aCSF1-CSF1R complex
                                is-aCSK-GAP-A.p62 complex
                                is-aCtf18 RFC-like complex
                                is-aCUGBP1-eIF2 complex
                                is-aCURI complex
                                is-aCVT complex
                                is-acyclin-dependent protein kinase 5 holoenzyme complex
                                is-acytochrome complex +
                                is-acytosolic tRNA wobble base thiouridylase complex
                                is-aDbf4-dependent protein kinase complex
                                is-aDBIRD complex
                                is-aDiaA complex
                                is-adivisome complex +
                                is-aDNA bending complex +
                                is-aDNA ligase III-XRCC1 complex
                                is-aDNA ligase IV complex
                                is-aDNA packaging complex +
                                is-aDNA polymerase III, clamp loader chi/psi subcomplex
                                is-aDNA polymerase III, clamp loader complex +
                                is-aDNA polymerase III, core complex +
                                is-aDNA polymerase III, proofreading complex
                                is-aDNA polymerase processivity factor complex +
                                is-aDNA recombinase mediator complex +
                                is-aDNA repair complex +
                                is-aDNA replication factor A complex
                                is-aDNA replication factor C complex +
                                is-aDNA replication factor C core complex
                                is-aDNA topoisomerase complex (ATP-hydrolyzing)
                                is-aDNA topoisomerase IV complex
                                is-aDnaB-DnaC complex
                                is-aDom34-Hbs1 complex
                                is-aDsl1p complex
                                is-aDUBm complex
                                is-aDxr protein complex
                                is-aE.F.G complex
                                is-aEARP complex
                                is-aegasyn-beta-glucuronidase complex
                                is-aeisosome filament
                                is-aEKC/KEOPS complex
                                is-aelectron transfer flavoprotein complex +
                                is-aElg1 RFC-like complex
                                is-aElongator holoenzyme complex
                                is-aendopeptidase Clp complex +
                                is-aendoplasmic reticulum chaperone complex
                                is-aenterobactin synthetase complex
                                is-aER membrane insertion complex +
                                is-aESCRT complex +
                                is-aeukaryotic translation elongation factor 1 complex
                                is-aeukaryotic translation initiation factor 2 complex
                                is-aeukaryotic translation initiation factor 2B complex
                                is-aeukaryotic translation initiation factor 3 complex +
                                is-aeukaryotic translation initiation factor 4F complex
                                is-aexocyst
                                is-aexomer complex
                                is-aexon-exon junction complex +
                                is-aexosome (RNase complex) +
                                is-aextracellular exosome complex +
                                is-aF-actin capping protein complex +
                                is-aFAl1-SGD1 complex
                                is-aFANCM-MHF complex
                                is-aFanconi anaemia nuclear complex
                                is-aFAR/SIN/STRIPAK complex
                                is-afatty acid beta-oxidation multienzyme complex +
                                is-afatty acid synthase complex
                                is-aferritin complex +
                                is-aFHF complex
                                is-afibrinogen complex
                                is-afilamentous actin
                                is-aformyl-methanofuran dehydrogenase (molybdenum enzyme) complex
                                is-aformyl-methanofuran dehydrogenase (tungsten enzyme) complex
                                is-aG-protein alpha(13)-synembrin complex
                                is-aG-protein alpha(i)1-synembrin complex
                                is-aG-protein alpha(o)-synembrin complex
                                is-aG-protein alpha(q)-synembrin complex
                                is-aG-protein beta/gamma-Btk complex
                                is-aG-protein beta/gamma-Raf-1 complex
                                is-aG-protein beta/gamma-subunit complex
                                is-aGAIT complex
                                is-agamma-tubulin complex +
                                is-aGARP complex
                                is-aGATA1-TAL1-TCF3-Lmo2 complex
                                is-aGATA2-TAL1-TCF3-Lmo2 complex
                                is-aGATOR2 complex
                                is-aGemin3-Gemin4-Gemin5 complex
                                is-aGemin6-Gemin7-unrip complex
                                is-aGET complex
                                is-aGID complex
                                is-aGLI-SUFU complex
                                is-aglucosidase II complex
                                is-aglutamyl-tRNA(Gln) amidotransferase complex
                                is-aglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
                                is-aGolgi transport complex
                                is-agrowth factor complex +
                                is-aGTPase activator complex +
                                is-aGtr1-Gtr2 GTPase complex
                                is-aguanyl-nucleotide exchange factor complex +
                                is-aguanylate cyclase complex, soluble
                                is-aH-NS-Cnu complex
                                is-aH-NS-Hha complex
                                is-ahaptoglobin-hemoglobin complex
                                is-aHedgehog signaling complex
                                is-ahemidesmosome associated protein complex +
                                is-ahemoglobin complex
                                is-aHICS complex
                                is-aHIR complex
                                is-aHolliday junction resolvase complex +
                                is-aHSP90-CDC37 chaperone complex
                                is-aI-kappaB/NF-kappaB complex +
                                is-aIg heavy chain-bound endoplasmic reticulum chaperone complex
                                is-aIKKalpha-IKKalpha complex
                                is-aIml1 complex
                                is-aimmunoglobulin complex +
                                is-ainflammasome complex +
                                is-ainhibin complex +
                                is-aintegrator complex
                                is-ainterferon regulatory factor complex +
                                is-ainterleukin-12 complex
                                is-ainterleukin-23 complex
                                is-ainterleukin-27 complex
                                is-ainterleukin-35 complex
                                is-aintermediate filament +
                                is-aintraciliary transport particle +
                                is-aintraciliary transport particle A
                                is-aintraciliary transport particle B
                                is-aIRE1-RACK1-PP2A complex
                                is-airon-sulfur cluster assembly complex
                                is-ajunctional membrane complex
                                is-aKelch-containing formin regulatory complex
                                is-aKibra-Ex-Mer complex
                                is-akinetochore +
                                is-aKu70:Ku80 complex
                                is-aL-cysteine desulfurase complex +
                                is-alaminin complex +
                                is-alarge latent transforming growth factor-beta complex
                                is-alarval serum protein complex
                                is-alateral cortical node
                                is-aLid2 complex
                                is-alight-harvesting complex +
                                is-aLINC complex +
                                is-aLsd1/2 complex
                                is-aLsm1-7-Pat1 complex
                                is-aluminal surveillance complex
                                is-alysosomal multienzyme complex
                                is-aMAD1 complex
                                is-aMAML1-RBP-Jkappa- ICN1 complex
                                is-aMAML2-RBP-Jkappa-ICN1 complex
                                is-aMAML2-RBP-Jkappa-ICN2 complex
                                is-aMAML2-RBP-Jkappa-ICN3 complex
                                is-aMAML2-RBP-Jkappa-ICN4 complex
                                is-aMAML3-RBP-Jkappa-ICN1 complex
                                is-aMAML3-RBP-Jkappa-ICN2 complex
                                is-aMAML3-RBP-Jkappa-ICN3 complex
                                is-aMAML3-RBP-Jkappa-ICN4 complex
                                is-aMCM complex +
                                is-aMCM core complex
                                is-aMcs4 RR-MAPKKK complex
                                is-aMECO complex
                                is-amedial cortical node
                                is-amediator complex
                                is-ameiotic recombination initiation complex
                                is-amembrane protein complex +
                                is-ametallochaperone complex +
                                is-amethionyl glutamyl tRNA synthetase complex
                                is-amethyl accepting chemotaxis protein complex
                                is-amethyl-tetrahydromethanopterin:coenzyme M methyltransferase complex
                                is-amicrotubule +
                                is-amicrotubule associated complex +
                                is-aMIS12/MIND type complex +
                                is-aMis6-Sim4 complex
                                is-amitochondrial protein complex +
                                is-amitotic checkpoint complex +
                                is-amitotic checkpoint complex, CDC20-MAD2 subcomplex
                                is-amitotic spindle assembly checkpoint MAD1-MAD2 complex
                                is-aMmi1 nuclear focus complex
                                is-aMMXD complex
                                is-amolybdopterin synthase complex
                                is-aMon1-Ccz1 complex
                                is-amonopolin complex
                                is-aMpp10 complex
                                is-aMre11 complex
                                is-amRNA cleavage factor complex +
                                is-amRNA editing complex +
                                is-aMTREC complex
                                is-aMyb complex
                                is-aMyo2p-Vac17p-Vac8p transport complex
                                is-amyosin complex +
                                is-aNAD(P)+ transhydrogenase complex (AB-specific)
                                is-anascent polypeptide-associated complex
                                is-aNdc80 complex
                                is-anexin complex
                                is-aNF-kappaB complex +
                                is-aNHE3/E3KARP/ACTN4 complex
                                is-anitrite reductase complex [NAD(P)H]
                                is-aNMS complex
                                is-aNoc complex +
                                is-aNOS2-CD74 complex
                                is-aNrd1 complex
                                is-aNsk1-Dlc1 complex
                                is-anuclear RNA export factor complex
                                is-anucleocytoplasmic shuttling complex +
                                is-anucleolus organizer region
                                is-anucleosome disassembly/reassembly complex
                                is-anucleotide-excision repair, DNA damage recognition complex +
                                is-aNURS complex
                                is-aorigin recognition complex +
                                is-aornithine carbamoyltransferase inhibitor complex
                                is-aP-TEFb-cap methyltransferase complex
                                is-aPAN complex
                                is-aPar3-APC-KIF3A complex
                                is-aparaferritin complex
                                is-aPcG protein complex +
                                is-aPCNA-p21 complex
                                is-aPCSK9-AnxA2 complex
                                is-aPCSK9-LDLR complex
                                is-aPDX1-PBX1b-MRG1 complex
                                is-aPeBoW complex
                                is-apeptidase inhibitor complex
                                is-aPex17p-Pex14p docking complex +
                                is-aphosphoenolpyruvate-dependent sugar phosphotransferase complex
                                is-apICln-Sm protein complex
                                is-apituitary gonadotropin complex +
                                is-apodosome
                                is-apolarisome +
                                is-apolkadots
                                is-apolycystin complex
                                is-apolyketide synthase complex +
                                is-aprefoldin complex
                                is-aprimosome complex +
                                is-aprotease inhibitor complex +
                                is-aproteasome accessory complex +
                                is-aproteasome activator complex
                                is-aproteasome complex +
                                is-aproteasome core complex +
                                is-aproteasome core complex, alpha-subunit complex +
                                is-aproteasome core complex, beta-subunit complex +
                                is-aproteasome regulatory particle +
                                is-aproteasome regulatory particle, base subcomplex +
                                is-aproteasome regulatory particle, lid subcomplex +
                                is-aproteasome-activating nucleotidase complex
                                is-aprotein complex involved in cell adhesion +
                                is-aprotein kinase CK2 complex
                                is-aPrp19 complex
                                is-aPTEX complex
                                is-aPwp2p-containing subcomplex of 90S preribosome
                                is-aPYM-mago-Y14 complex
                                is-apyrophosphate-dependent phosphofructokinase complex +
                                is-apyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex
                                is-apyrophosphate-dependent phosphofructokinase complex, beta-subunit complex
                                is-apyroptosome complex
                                is-aR2TP complex
                                is-aRad17 RFC-like complex
                                is-aradial spoke +
                                is-aradial spoke stalk
                                is-aradial spokehead
                                is-araps-insc complex
                                is-aRasGAP-Fyn-Lyn-Yes complex
                                is-aRAVE complex
                                is-aRC-1 DNA recombination complex
                                is-aRCAF complex
                                is-areceptor complex +
                                is-aRecFOR complex
                                is-aRecQ helicase-Topo III complex
                                is-areplication fork protection complex
                                is-areplication inhibiting complex +
                                is-aRES complex
                                is-aRGS6-DNMT1-DMAP1 complex
                                is-aRhino-Deadlock-Cutoff Complex
                                is-aribonuclease H2 complex
                                is-aRix1 complex
                                is-aRNA cap binding complex +
                                is-aRNA polymerase II, RPB4-RPB7 subcomplex
                                is-aRPAP3/R2TP/prefoldin-like complex
                                is-aRQC complex
                                is-aRvs161p-Rvs167p complex
                                is-aRZZ complex
                                is-aS100A8 complex
                                is-ascaffoldin complex
                                is-aSCAR complex
                                is-aScrib-APC complex
                                is-aScrib-APC-beta-catenin complex
                                is-aSeh1-associated complex +
                                is-aseparase-securin complex
                                is-aseptin complex +
                                is-aSid2-Mob1 complex
                                is-asigma factor antagonist complex
                                is-asingle-stranded DNA-binding protein complex
                                is-aSki complex
                                is-aSlx1-Slx4 complex
                                is-aSMAD protein complex +
                                is-aSMC loading complex
                                is-aSmc5-Smc6 complex
                                is-aSMN complex
                                is-aSMN-Gemin2 complex
                                is-aSMN-Sm protein complex +
                                is-aSOD1-Bcl-2 complex
                                is-aSOD1-calcineurin complex
                                is-aSOSS complex
                                is-aspitzenkorper
                                is-aSsuD-SsuE complex
                                is-aSte12p-Dig1p-Dig2p complex
                                is-astereocilia ankle link complex
                                is-asteroid hormone aporeceptor complex
                                is-asulfite reductase complex (NADPH)
                                is-asumoylated E2 ligase complex
                                is-asurvivin complex
                                is-aSWI/SNF superfamily-type complex +
                                is-aSwi5-Swi2 complex
                                is-aSyp1 complex
                                is-at-UTP complex
                                is-aTACC/TOG complex
                                is-aTAM protein secretion complex
                                is-aTBK1-IKKE-DDX3 complex
                                is-aTCR signalosome
                                is-aTCTN-B9D complex
                                is-aTEAD-2 multiprotein complex
                                is-aTec1p-Ste12p-Dig1p complex
                                is-aTHO complex +
                                is-athrombospondin complex
                                is-atitin-telethonin complex
                                is-aTor2-Mei2-Ste11 complex
                                is-aTORC1 complex [GO:0031931] (7 genes, 7 annotations)
                                is-aTORC2 complex
                                is-aTRAF2-GSTP1 complex
                                is-aTRAMP complex
                                is-atrans-synaptic protein complex
                                is-atranscription elongation factor complex +
                                is-atranscription export complex +
                                is-atranscription export complex 2
                                is-atranscription factor complex +
                                is-atranscriptional repressor complex +
                                is-atransforming growth factor beta activated kinase 1 complex
                                is-atranslation release factor complex
                                is-atranslation repressor complex +
                                is-atransporter complex +
                                is-aTRAPP complex +
                                is-atricarboxylic acid cycle enzyme complex +
                                is-atRNA-splicing ligase complex
                                is-atroponin complex +
                                is-aTSC1-TSC2 complex
                                is-atubulin complex
                                is-atubulin folding cofactor complex
                                is-atubulobulbar complex
                                is-atype I protein secretion system complex
                                is-atype II protein secretion system complex
                                is-atype III protein secretion system complex
                                is-atype IV secretion system complex
                                is-atype V protein secretion system complex
                                is-atype VI protein secretion system complex
                                is-aU2AF
                                is-aubiquitin conjugating enzyme complex +
                                is-aUFD1-NPL4 complex
                                is-aUSH2 complex
                                is-aUTP-C complex
                                is-avacuolar transporter chaperone complex
                                is-aVCP-NSFL1C complex
                                is-aviral integration complex
                                is-aviral portal complex
                                is-aviral scaffold
                                is-aviral terminase complex +
                                is-aviral transcriptional complex
                                is-avirus terminase, large subunit
                                is-aVRK3/VHR/ERK complex
                                is-aWASH complex
                                is-aY-shaped link
                                is-azona pellucida receptor complex


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory