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Gene Ontology Browser
Term Detail
GO term:CD95 death-inducing signaling complex
Synonym: CD95 death-inducing signalling complex
Synonym: CD95 DISC
Synonym: Fas death-inducing signaling complex
GO id:GO:0031265
Definition:A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
Number of paths to term: 10

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-acell periphery
                                        part-ofplasma membrane
                                                part-ofplasma membrane part
                                                        is-adeath-inducing signaling complex
                                                                is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                                is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aplasma membrane
                                        part-ofplasma membrane part
                                                is-adeath-inducing signaling complex
                                                        is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                        is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aplasma membrane part
                                        is-adeath-inducing signaling complex
                                                is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-acell periphery
                                part-ofplasma membrane
                                        part-ofplasma membrane part
                                                is-adeath-inducing signaling complex
                                                        is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                        is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aplasma membrane
                                part-ofplasma membrane part
                                        is-adeath-inducing signaling complex
                                                is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aplasma membrane part
                                is-adeath-inducing signaling complex
                                        is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                        is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-amacromolecular complex
                        is-aprotein complex
                                is-adeath-inducing signaling complex
                                        is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                        is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aplasma membrane part
                                        is-adeath-inducing signaling complex
                                                is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-amembrane
                        is-aplasma membrane
                                part-ofplasma membrane part
                                        is-adeath-inducing signaling complex
                                                is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                                is-aTRAIL death-inducing signaling complex


Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aplasma membrane part
                                is-adeath-inducing signaling complex
                                        is-aCD95 death-inducing signaling complex [GO:0031265] (4 genes, 5 annotations)
                                        is-aTRAIL death-inducing signaling complex


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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory