| GO term: | death-inducing signaling complex |
| Synonym: | death-inducing signalling complex |
| Synonym: | death receptor-induced signaling complex |
| Synonym: | death receptor-induced signalling complex |
| Synonym: | DISC |
| Synonym: | DISC protein complex |
| GO id: | GO:0031264 |
| Definition: | A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor. |
| Number of paths to term: | 10 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship