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Gene Ontology Browser
Term Detail
GO term:intrinsic component of membrane
Synonym: intrinsic to membrane
GO id:GO:0031224
Definition:The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
CommentsNote that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane
                        part-ofmembrane part
                                is-aalpha-1,6-mannosyltransferase complex
                                is-achaperone-mediated autophagy translocation complex
                                is-adolichyl-phosphate-mannose-protein mannosyltransferase complex +
                                is-aDsc E3 ubiquitin ligase complex
                                is-aendoplasmic reticulum membrane +
                                is-aendoplasmic reticulum palmitoyltransferase complex +
                                is-aER ubiquitin ligase complex +
                                is-aextrinsic component of membrane +
                                is-afatty acid elongase complex
                                is-aGPI-anchor transamidase complex
                                is-aintrinsic component of membrane [GO:0031224] (5882 genes, 8436 annotations)
                                        is-aanchored component of membrane +
                                        is-aintegral component of membrane +
                                        is-aintrinsic component of cell outer membrane +
                                        is-aintrinsic component of endoplasmic reticulum membrane +
                                        is-aintrinsic component of organelle membrane +
                                        is-aintrinsic component of plasma membrane +
                                        is-aintrinsic component of pre-autophagosomal structure membrane +
                                        is-aintrinsic component of thylakoid membrane +
                                is-aIre1 complex
                                is-aleaflet of membrane bilayer
                                is-alipopolysaccharide receptor complex
                                is-amembrane protein complex +
                                is-amembrane region +
                                is-amitochondrial membrane part +
                                is-aNADH dehydrogenase complex +
                                is-aNem1-Spo7 phosphatase complex
                                is-anuclear membrane part +
                                is-anuclear outer membrane +
                                is-aoligosaccharyltransferase complex +
                                is-aperinuclear endoplasmic reticulum membrane
                                is-aphosphatidylinositol 3-kinase complex +
                                is-aphotosystem II oxygen evolving complex
                                is-aplasma membrane part +
                                is-aprospore membrane spindle pole body attachment site
                                is-arespiratory chain +
                                is-aside of membrane +
                                is-asuccinate dehydrogenase complex +
                                is-atransmembrane transporter complex +


obsolete Gene_Ontology
        is-acellular_component
                is-amembrane part
                        is-aalpha-1,6-mannosyltransferase complex
                        is-achaperone-mediated autophagy translocation complex
                        is-adolichyl-phosphate-mannose-protein mannosyltransferase complex +
                        is-aDsc E3 ubiquitin ligase complex
                        is-aendoplasmic reticulum membrane +
                        is-aendoplasmic reticulum palmitoyltransferase complex +
                        is-aER ubiquitin ligase complex +
                        is-aextrinsic component of membrane +
                        is-afatty acid elongase complex
                        is-aGPI-anchor transamidase complex
                        is-aintrinsic component of membrane [GO:0031224] (5882 genes, 8436 annotations)
                                is-aanchored component of membrane +
                                is-aintegral component of membrane +
                                is-aintrinsic component of cell outer membrane +
                                is-aintrinsic component of endoplasmic reticulum membrane +
                                is-aintrinsic component of organelle membrane +
                                is-aintrinsic component of plasma membrane +
                                is-aintrinsic component of pre-autophagosomal structure membrane +
                                is-aintrinsic component of thylakoid membrane +
                        is-aIre1 complex
                        is-aleaflet of membrane bilayer
                        is-alipopolysaccharide receptor complex
                        is-amembrane protein complex +
                        is-amembrane region +
                        is-amitochondrial membrane part +
                        is-aNADH dehydrogenase complex +
                        is-aNem1-Spo7 phosphatase complex
                        is-anuclear membrane part +
                        is-anuclear outer membrane +
                        is-aoligosaccharyltransferase complex +
                        is-aperinuclear endoplasmic reticulum membrane
                        is-aphosphatidylinositol 3-kinase complex +
                        is-aphotosystem II oxygen evolving complex
                        is-aplasma membrane part +
                        is-aprospore membrane spindle pole body attachment site
                        is-arespiratory chain +
                        is-aside of membrane +
                        is-asuccinate dehydrogenase complex +
                        is-atransmembrane transporter complex +


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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory