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Gene Ontology Browser
Term Detail
GO term:regulation of proteolysis
Synonym: regulation of peptidolysis
GO id:GO:0030162
Definition:Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Number of paths to term: 12

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-anegative regulation of protein metabolic process +
                                                        is-apositive regulation of protein metabolic process +
                                                        is-aregulation of amyloid precursor protein catabolic process +
                                                        is-aregulation of angiotensin metabolic process +
                                                        is-aregulation of cellular protein metabolic process +
                                                        is-aregulation of cytokine biosynthetic process +
                                                        is-aregulation of glycoprotein metabolic process +
                                                        is-aregulation of hemoglobin biosynthetic process +
                                                        is-aregulation of lipoprotein metabolic process +
                                                        is-aregulation of protein activation cascade +
                                                        is-aregulation of protein catabolic process +
                                                        is-aregulation of protein maturation +
                                                        is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                                is-anegative regulation of proteolysis +
                                                                is-apositive regulation of proteolysis +
                                                                is-aregulation of membrane protein ectodomain proteolysis +
                                                                is-aregulation of peptidase activity +
                                                                is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of metabolic process
                                        is-aregulation of primary metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-anegative regulation of protein metabolic process +
                                                        is-apositive regulation of protein metabolic process +
                                                        is-aregulation of amyloid precursor protein catabolic process +
                                                        is-aregulation of angiotensin metabolic process +
                                                        is-aregulation of cellular protein metabolic process +
                                                        is-aregulation of cytokine biosynthetic process +
                                                        is-aregulation of glycoprotein metabolic process +
                                                        is-aregulation of hemoglobin biosynthetic process +
                                                        is-aregulation of lipoprotein metabolic process +
                                                        is-aregulation of protein activation cascade +
                                                        is-aregulation of protein catabolic process +
                                                        is-aregulation of protein maturation +
                                                        is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                                is-anegative regulation of proteolysis +
                                                                is-apositive regulation of proteolysis +
                                                                is-aregulation of membrane protein ectodomain proteolysis +
                                                                is-aregulation of peptidase activity +
                                                                is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aproteolysis
                                                        is-amembrane protein proteolysis +
                                                        negatively-regulatesnegative regulation of proteolysis +
                                                        positively-regulatespositive regulation of proteolysis +
                                                        is-aproteolysis in other organism +
                                                        is-aproteolysis involved in cellular protein catabolic process +
                                                        regulatesregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                                is-anegative regulation of proteolysis +
                                                                is-apositive regulation of proteolysis +
                                                                is-aregulation of membrane protein ectodomain proteolysis +
                                                                is-aregulation of peptidase activity +
                                                                is-aregulation of proteolysis involved in cellular protein catabolic process +
                                                        is-aself proteolysis +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                regulatesregulation of protein metabolic process
                                                        is-anegative regulation of protein metabolic process +
                                                        is-apositive regulation of protein metabolic process +
                                                        is-aregulation of amyloid precursor protein catabolic process +
                                                        is-aregulation of angiotensin metabolic process +
                                                        is-aregulation of cellular protein metabolic process +
                                                        is-aregulation of cytokine biosynthetic process +
                                                        is-aregulation of glycoprotein metabolic process +
                                                        is-aregulation of hemoglobin biosynthetic process +
                                                        is-aregulation of lipoprotein metabolic process +
                                                        is-aregulation of protein activation cascade +
                                                        is-aregulation of protein catabolic process +
                                                        is-aregulation of protein maturation +
                                                        is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                                is-anegative regulation of proteolysis +
                                                                is-apositive regulation of proteolysis +
                                                                is-aregulation of membrane protein ectodomain proteolysis +
                                                                is-aregulation of peptidase activity +
                                                                is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        regulatesregulation of macromolecule metabolic process
                                                is-aregulation of protein metabolic process
                                                        is-anegative regulation of protein metabolic process +
                                                        is-apositive regulation of protein metabolic process +
                                                        is-aregulation of amyloid precursor protein catabolic process +
                                                        is-aregulation of angiotensin metabolic process +
                                                        is-aregulation of cellular protein metabolic process +
                                                        is-aregulation of cytokine biosynthetic process +
                                                        is-aregulation of glycoprotein metabolic process +
                                                        is-aregulation of hemoglobin biosynthetic process +
                                                        is-aregulation of lipoprotein metabolic process +
                                                        is-aregulation of protein activation cascade +
                                                        is-aregulation of protein catabolic process +
                                                        is-aregulation of protein maturation +
                                                        is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                                is-anegative regulation of proteolysis +
                                                                is-apositive regulation of proteolysis +
                                                                is-aregulation of membrane protein ectodomain proteolysis +
                                                                is-aregulation of peptidase activity +
                                                                is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aproteolysis
                                                is-amembrane protein proteolysis +
                                                negatively-regulatesnegative regulation of proteolysis +
                                                positively-regulatespositive regulation of proteolysis +
                                                is-aproteolysis in other organism +
                                                is-aproteolysis involved in cellular protein catabolic process +
                                                regulatesregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +
                                                is-aself proteolysis +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        regulatesregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                regulatesregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        regulatesregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of macromolecule metabolic process
                                        is-aregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of metabolic process
                                is-aregulation of primary metabolic process
                                        is-aregulation of protein metabolic process
                                                is-anegative regulation of protein metabolic process +
                                                is-apositive regulation of protein metabolic process +
                                                is-aregulation of amyloid precursor protein catabolic process +
                                                is-aregulation of angiotensin metabolic process +
                                                is-aregulation of cellular protein metabolic process +
                                                is-aregulation of cytokine biosynthetic process +
                                                is-aregulation of glycoprotein metabolic process +
                                                is-aregulation of hemoglobin biosynthetic process +
                                                is-aregulation of lipoprotein metabolic process +
                                                is-aregulation of protein activation cascade +
                                                is-aregulation of protein catabolic process +
                                                is-aregulation of protein maturation +
                                                is-aregulation of proteolysis [GO:0030162] (590 genes, 893 annotations)
                                                        is-anegative regulation of proteolysis +
                                                        is-apositive regulation of proteolysis +
                                                        is-aregulation of membrane protein ectodomain proteolysis +
                                                        is-aregulation of peptidase activity +
                                                        is-aregulation of proteolysis involved in cellular protein catabolic process +


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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory