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Gene Ontology Browser
Term Detail
GO term:chemokine binding
GO id:GO:0019956
Definition:Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-aprotein binding
                                is-acytokine binding
                                        is-aBMP binding
                                        is-achemokine binding [GO:0019956] (14 genes, 25 annotations)
                                                is-aC-C chemokine binding +
                                                is-aC-X-C chemokine binding +
                                                is-aC-X3-C chemokine binding
                                        is-aciliary neurotrophic factor binding
                                        is-agranulocyte colony-stimulating factor binding
                                        is-agranulocyte macrophage colony-stimulating factor complex binding
                                        is-ahigh mobility group box 1 binding
                                        is-ainterferon binding +
                                        is-ainterleukin-1 binding
                                        is-ainterleukin-10 binding
                                        is-ainterleukin-11 binding
                                        is-ainterleukin-12 binding +
                                        is-ainterleukin-13 binding
                                        is-ainterleukin-14 binding
                                        is-ainterleukin-15 binding
                                        is-ainterleukin-16 binding
                                        is-ainterleukin-17 binding
                                        is-ainterleukin-18 binding +
                                        is-ainterleukin-19 binding
                                        is-ainterleukin-2 binding
                                        is-ainterleukin-20 binding
                                        is-ainterleukin-21 binding
                                        is-ainterleukin-22 binding
                                        is-ainterleukin-23 binding
                                        is-ainterleukin-24 binding
                                        is-ainterleukin-25 binding
                                        is-ainterleukin-26 binding
                                        is-ainterleukin-27 binding
                                        is-ainterleukin-3 binding
                                        is-ainterleukin-33 binding
                                        is-ainterleukin-35 binding
                                        is-ainterleukin-4 binding
                                        is-ainterleukin-5 binding
                                        is-ainterleukin-6 binding
                                        is-ainterleukin-7 binding
                                        is-ainterleukin-9 binding
                                        is-amacrophage migration inhibitory factor binding
                                        is-atransforming growth factor beta binding
                                        is-atumor necrosis factor binding +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory