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Gene Ontology Browser
Term Detail
GO term:histone-lysine N-methyltransferase activity
Synonym: histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity
Synonym: histone-lysine N-methylase activity
Synonym: protein (lysine) methyltransferase activity
Synonym: protein methylase 3 activity
Synonym: protein methylase III activity
Synonym: protein methyltransferase II activity
Synonym: S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity
Synonym: S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity
GO id:GO:0018024
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aN-methyltransferase activity
                                                        is-alysine N-methyltransferase activity
                                                                is-aprotein-lysine N-methyltransferase activity
                                                                        is-a[cytochrome c]-lysine N-methyltransferase activity
                                                                        is-acalmodulin-lysine N-methyltransferase activity
                                                                        is-ahistone-lysine N-methyltransferase activity [GO:0018024] (39 genes, 74 annotations)
                                                                                is-ahistone methyltransferase activity (H3-K27 specific)
                                                                                is-ahistone methyltransferase activity (H3-K36 specific)
                                                                                is-ahistone methyltransferase activity (H3-K4 specific)
                                                                                is-ahistone methyltransferase activity (H3-K79 specific)
                                                                                is-ahistone methyltransferase activity (H3-K9 specific)
                                                                                is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aprotein methyltransferase activity
                                                        is-ahistone methyltransferase activity
                                                                is-ahistone-arginine N-methyltransferase activity +
                                                                is-ahistone-glutamine methyltransferase activity
                                                                is-ahistone-lysine N-methyltransferase activity [GO:0018024] (39 genes, 74 annotations)
                                                                        is-ahistone methyltransferase activity (H3-K27 specific)
                                                                        is-ahistone methyltransferase activity (H3-K36 specific)
                                                                        is-ahistone methyltransferase activity (H3-K4 specific)
                                                                        is-ahistone methyltransferase activity (H3-K79 specific)
                                                                        is-ahistone methyltransferase activity (H3-K9 specific)
                                                                        is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aprotein methyltransferase activity
                                                        is-aprotein-lysine N-methyltransferase activity
                                                                is-a[cytochrome c]-lysine N-methyltransferase activity
                                                                is-acalmodulin-lysine N-methyltransferase activity
                                                                is-ahistone-lysine N-methyltransferase activity [GO:0018024] (39 genes, 74 annotations)
                                                                        is-ahistone methyltransferase activity (H3-K27 specific)
                                                                        is-ahistone methyltransferase activity (H3-K36 specific)
                                                                        is-ahistone methyltransferase activity (H3-K4 specific)
                                                                        is-ahistone methyltransferase activity (H3-K79 specific)
                                                                        is-ahistone methyltransferase activity (H3-K9 specific)
                                                                        is-ahistone methyltransferase activity (H4-K20 specific)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring one-carbon groups
                                        is-amethyltransferase activity
                                                is-aS-adenosylmethionine-dependent methyltransferase activity
                                                        is-alysine N-methyltransferase activity
                                                                is-aprotein-lysine N-methyltransferase activity
                                                                        is-a[cytochrome c]-lysine N-methyltransferase activity
                                                                        is-acalmodulin-lysine N-methyltransferase activity
                                                                        is-ahistone-lysine N-methyltransferase activity [GO:0018024] (39 genes, 74 annotations)
                                                                                is-ahistone methyltransferase activity (H3-K27 specific)
                                                                                is-ahistone methyltransferase activity (H3-K36 specific)
                                                                                is-ahistone methyltransferase activity (H3-K4 specific)
                                                                                is-ahistone methyltransferase activity (H3-K79 specific)
                                                                                is-ahistone methyltransferase activity (H3-K9 specific)
                                                                                is-ahistone methyltransferase activity (H4-K20 specific)


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory