| GO term: | oxidative phosphorylation uncoupler activity |
| Synonym: | mitochondrial uncoupling protein activity |
| Synonym: | uncoupling protein activity |
| GO id: | GO:0017077 |
| Definition: | Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functiontransporter activitytransmembrane transporter activityacetate ester transmembrane transporter activity +active transmembrane transporter activity +azole transmembrane transporter activity +drug transmembrane transporter activity +efflux transmembrane transporter activity +galactosamine transmembrane transporter activity +hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances +lipo-chitin oligosaccharide transmembrane transporter activity +organic hydroxy compound transmembrane transporter activity +organic phosphonate transmembrane transporter activity +oxidative phosphorylation uncoupler activity [GO:0017077] (2 genes, 3 annotations)hydrophobic uncoupler:hydrogen antiporter activitypassive transmembrane transporter activity +phosphate transmembrane transporter activity +poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activitysalt transmembrane transporter activity +substrate-specific transmembrane transporter activity +sulfur compound transmembrane transporter activity +transmembrane electron transfer carrier +uptake transmembrane transporter activity +vitamin transmembrane transporter activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/22/2013 MGI 5.13 |
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