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Term Detail
GO term:Rho GTPase binding
Synonym: Rho interactor activity
Synonym: Rhophilin
GO id:GO:0017048
Alternate id: GO:0017031
Definition:Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                        is-aprotein binding
                                is-aenzyme binding
                                        is-aGTPase binding
                                                is-asmall GTPase binding
                                                        is-aRas GTPase binding
                                                                is-aRab GTPase binding
                                                                is-aRal GTPase binding
                                                                is-aRan GTPase binding
                                                                is-aRho GTPase binding [GO:0017048] (86 genes, 103 annotations)
                                                                        is-aGTP-Rho binding
                                                                        is-aRac GTPase binding

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory