| GO term: | carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
| GO id: | GO:0016884 |
| Definition: | Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityligase activityligase activity, forming carbon-nitrogen bonds5-(carboxyamino)imidazole ribonucleotide synthase activityacid-amino acid ligase activity +acid-ammonia (or amide) ligase activity +adenylosuccinate synthase activityargininosuccinate synthase activityAtg8 ligase activitybiotin carboxylase activitybiotin-protein ligase activity +carbamoyl-phosphate synthase (ammonia) activitycarbon-nitrogen ligase activity, with glutamine as amido-N-donor [GO:0016884] (9 genes, 11 annotations)adenosylcobyric acid synthase (glutamine-hydrolyzing) activityasparagine synthase (glutamine-hydrolyzing) activityasparaginyl-tRNA synthase (glutamine-hydrolyzing) activitycarbamoyl-phosphate synthase (glutamine-hydrolyzing) activitycobyrinate a,c-diamide synthase activityglutaminyl-tRNA synthase (glutamine-hydrolyzing) activityGMP synthase (glutamine-hydrolyzing) activityhydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activityNAD+ synthase (glutamine-hydrolyzing) activityphosphoribosylformylglycinamidine synthase activitycitrate-L-glutamate ligase activityCTP synthase activitycyclo-ligase activity +formate-dihydrofolate ligase activityformate-tetrahydrofolate ligase activityglutamate-methylamine ligase activityGMP synthase activityimidazoleacetate-phosphoribosyldiphosphate ligase activitylipoate-protein ligase activity +N-acetyl-L-aspartate-L-glutamate ligase activityphosphoribosylamine-glycine ligase activityribose-5-phosphate-ammonia ligase activitysulfinylpropanyl adenylate synthasetRNA(Ile)-lysidine synthase activityurea carboxylase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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