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Gene Ontology Browser
Term Detail
GO term:ligase activity
Synonym: synthetase activity
GO id:GO:0016874
Definition:Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-acatalysis of free radical formation +
                        is-acyclase activity +
                        is-adeaminase activity +
                        is-ademethylase activity +
                        is-afirst spliceosomal transesterification activity
                        is-aglycogen debranching enzyme activity +
                        is-ahydrolase activity +
                        is-aintegrase activity +
                        is-aisomerase activity +
                        is-aligase activity [GO:0016874] (408 genes, 3213 annotations)
                                is-abeta-alanyl-dopamine synthase activity
                                is-adelta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity
                                is-aligase activity, forming carbon-carbon bonds +
                                is-aligase activity, forming carbon-nitrogen bonds +
                                is-aligase activity, forming carbon-oxygen bonds +
                                is-aligase activity, forming carbon-sulfur bonds +
                                is-aligase activity, forming nitrogen-metal bonds +
                                is-aligase activity, forming phosphoric ester bonds +
                                is-aO antigen ligase activity
                        is-alyase activity +
                        is-aMo-molybdopterin cofactor sulfurase activity
                        is-amolybdopterin synthase activity
                        is-aN-ethylammeline chlorohydrolase activity
                        is-aoxidoreductase activity +
                        is-aphenylacetaldehyde synthase activity
                        is-aphytoene synthase activity
                        is-aquinolinate synthetase A activity
                        is-aradical SAM enzyme activity +
                        is-arecombinase activity
                        is-aretroviral strand transfer activity
                        is-asecond spliceosomal transesterification activity
                        is-asite-specific recombinase activity +
                        is-asite-specific telomere resolvase activity
                        is-atransferase activity +
                        is-atransposase activity
                        is-aUDP-L-rhamnose synthase activity
                        is-aversicolorin B synthase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory