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Term Detail
GO term:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
Synonym: P-type ATPase activity
Synonym: zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
GO id:GO:0015662
Definition:Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on acid anhydrides
                                        is-ahydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
                                                is-aATPase activity, coupled to transmembrane movement of substances
                                                        is-aATPase activity, coupled to transmembrane movement of ions
                                                                is-aanion transmembrane-transporting ATPase activity +
                                                                is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                        is-acadmium-exporting ATPase activity
                                                                        is-acalcium-transporting ATPase activity +
                                                                        is-achloride-transporting ATPase activity
                                                                        is-acopper-transporting ATPase activity +
                                                                        is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                        is-amagnesium-importing ATPase activity
                                                                        is-apotassium-transporting ATPase activity +
                                                                        is-asilver-exporting ATPase activity
                                                                        is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                        is-azinc-exporting ATPase activity
                                                                is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                                is-acation-transporting ATPase activity +


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on acid anhydrides
                                        is-ahydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
                                                is-apyrophosphatase activity
                                                        is-anucleoside-triphosphatase activity
                                                                is-aATPase activity
                                                                        is-aATPase activity, coupled
                                                                                is-aATPase activity, coupled to movement of substances
                                                                                        is-aATPase activity, coupled to transmembrane movement of substances
                                                                                                is-aATPase activity, coupled to transmembrane movement of ions
                                                                                                        is-aanion transmembrane-transporting ATPase activity +
                                                                                                        is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                                                                is-acadmium-exporting ATPase activity
                                                                                                                is-acalcium-transporting ATPase activity +
                                                                                                                is-achloride-transporting ATPase activity
                                                                                                                is-acopper-transporting ATPase activity +
                                                                                                                is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                                                                is-amagnesium-importing ATPase activity
                                                                                                                is-apotassium-transporting ATPase activity +
                                                                                                                is-asilver-exporting ATPase activity
                                                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                                                is-azinc-exporting ATPase activity
                                                                                                        is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                                                                        is-acation-transporting ATPase activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aATPase activity, coupled to transmembrane movement of ions
                                                        is-aanion transmembrane-transporting ATPase activity +
                                                        is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                is-acadmium-exporting ATPase activity
                                                                is-acalcium-transporting ATPase activity +
                                                                is-achloride-transporting ATPase activity
                                                                is-acopper-transporting ATPase activity +
                                                                is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                is-amagnesium-importing ATPase activity
                                                                is-apotassium-transporting ATPase activity +
                                                                is-asilver-exporting ATPase activity
                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                is-azinc-exporting ATPase activity
                                                        is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                        is-acation-transporting ATPase activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-aactive transmembrane transporter activity
                                        is-aprimary active transmembrane transporter activity
                                                is-aP-P-bond-hydrolysis-driven transmembrane transporter activity
                                                        is-aATPase activity, coupled to transmembrane movement of substances
                                                                is-aATPase activity, coupled to transmembrane movement of ions
                                                                        is-aanion transmembrane-transporting ATPase activity +
                                                                        is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                                is-acadmium-exporting ATPase activity
                                                                                is-acalcium-transporting ATPase activity +
                                                                                is-achloride-transporting ATPase activity
                                                                                is-acopper-transporting ATPase activity +
                                                                                is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                                is-amagnesium-importing ATPase activity
                                                                                is-apotassium-transporting ATPase activity +
                                                                                is-asilver-exporting ATPase activity
                                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                                is-azinc-exporting ATPase activity
                                                                        is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                                        is-acation-transporting ATPase activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-ahydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
                                        is-aATPase activity, coupled to transmembrane movement of substances
                                                is-aATPase activity, coupled to transmembrane movement of ions
                                                        is-aanion transmembrane-transporting ATPase activity +
                                                        is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                is-acadmium-exporting ATPase activity
                                                                is-acalcium-transporting ATPase activity +
                                                                is-achloride-transporting ATPase activity
                                                                is-acopper-transporting ATPase activity +
                                                                is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                is-amagnesium-importing ATPase activity
                                                                is-apotassium-transporting ATPase activity +
                                                                is-asilver-exporting ATPase activity
                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                is-azinc-exporting ATPase activity
                                                        is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                        is-acation-transporting ATPase activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aATPase activity, coupled to transmembrane movement of ions
                                                        is-aanion transmembrane-transporting ATPase activity +
                                                        is-aATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [GO:0015662] (35 genes, 43 annotations)
                                                                is-acadmium-exporting ATPase activity
                                                                is-acalcium-transporting ATPase activity +
                                                                is-achloride-transporting ATPase activity
                                                                is-acopper-transporting ATPase activity +
                                                                is-ahydrogen-exporting ATPase activity, phosphorylative mechanism
                                                                is-amagnesium-importing ATPase activity
                                                                is-apotassium-transporting ATPase activity +
                                                                is-asilver-exporting ATPase activity
                                                                is-asodium-exporting ATPase activity, phosphorylative mechanism
                                                                is-azinc-exporting ATPase activity
                                                        is-aATPase activity, coupled to transmembrane movement of ions, rotational mechanism +
                                                        is-acation-transporting ATPase activity +


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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory