| GO term: | cell aging |
| Synonym: | cell ageing |
| GO id: | GO:0007569 |
| Definition: | An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469). |
| Number of paths to term: | 4 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processcellular processsingle-organism cellular processactin cortical patch organization +actin filament-based process +blood microparticle formation +cell activation +cell adhesion +cell adhesion molecule production +cell aging [GO:0007569] (65 genes, 89 annotations)cellular senescence +chronological cell aging +negative regulation of cell aging +nucleolar fragmentation +positive regulation of cell aging +progressive alteration of chromatin involved in cell aging +regulation of cell aging +replicative cell aging +replicative senescencecell communication +cell competition in a multicellular organismcell cycle +cell cycle process +cell death +cell division +cell growth +cell junction organization +cell projection organization +cell recognition +cell wall organization or biogenesis +cellular component disassembly +cellular component maintenance +cellular component movement +cellular developmental process +cellular homeostasis +cellular localization +cellular membrane organization +cellular pigmentation +cellular potassium ion transport +cellular response to stimulus +chromosome number maintenancechromosome segregation +contact inhibition +cytoplasm organization +dendritic spine organization +DNA packaging +ensheathment of neurons +establishment or maintenance of cell polarity +establishment or maintenance of cell type involved in phenotypic switchingexecution phase of apoptosis +external encapsulating structure organization +extracellular structure organization +fibril organization +G0 to G1 transition +G1 to G0 transition +gene silencing +generation of a signal involved in cell-cell signaling +intercellular transport +intermediate filament-based process +light absorption +maintenance of blood-brain barriermaintenance of location in cell +membrane docking +microtubule organizing center attachment site organizationmicrotubule-based process +negative regulation of cellular component organization +nucleoid organization +organelle organization +periplasmic space organizationphotoreceptor cell outer segment organizationplasmid maintenance +plastoglobule organizationregulation of cellular component size +reversion of cell type to default state involved in phenotypic switchingsecretion by cell +signal maturation +signal release +single-celled organism vegetative growth phase +stomatal movement +synapse organization +syncytium formation +terminal button organization +translational initiation +transmembrane transport +transposition +vesicle targeting +biological_processdevelopmental processsingle-organism developmental processagingage-dependent behavioral declineage-dependent general metabolic decline +cell aging [GO:0007569] (65 genes, 89 annotations)cellular senescence +chronological cell aging +negative regulation of cell aging +nucleolar fragmentation +positive regulation of cell aging +progressive alteration of chromatin involved in cell aging +regulation of cell aging +replicative cell aging +replicative senescencefruit ripening +multicellular organismal aging +organ senescence +biological_processsingle-organism processsingle-organism cellular processactin cortical patch organization +actin filament-based process +blood microparticle formation +cell activation +cell adhesion +cell adhesion molecule production +cell aging [GO:0007569] (65 genes, 89 annotations)cellular senescence +chronological cell aging +negative regulation of cell aging +nucleolar fragmentation +positive regulation of cell aging +progressive alteration of chromatin involved in cell aging +regulation of cell aging +replicative cell aging +replicative senescencecell communication +cell competition in a multicellular organismcell cycle +cell cycle process +cell death +cell division +cell growth +cell junction organization +cell projection organization +cell recognition +cell wall organization or biogenesis +cellular component disassembly +cellular component maintenance +cellular component movement +cellular developmental process +cellular homeostasis +cellular localization +cellular membrane organization +cellular pigmentation +cellular potassium ion transport +cellular response to stimulus +chromosome number maintenancechromosome segregation +contact inhibition +cytoplasm organization +dendritic spine organization +DNA packaging +ensheathment of neurons +establishment or maintenance of cell polarity +establishment or maintenance of cell type involved in phenotypic switchingexecution phase of apoptosis +external encapsulating structure organization +extracellular structure organization +fibril organization +G0 to G1 transition +G1 to G0 transition +gene silencing +generation of a signal involved in cell-cell signaling +intercellular transport +intermediate filament-based process +light absorption +maintenance of blood-brain barriermaintenance of location in cell +membrane docking +microtubule organizing center attachment site organizationmicrotubule-based process +negative regulation of cellular component organization +nucleoid organization +organelle organization +periplasmic space organizationphotoreceptor cell outer segment organizationplasmid maintenance +plastoglobule organizationregulation of cellular component size +reversion of cell type to default state involved in phenotypic switchingsecretion by cell +signal maturation +signal release +single-celled organism vegetative growth phase +stomatal movement +synapse organization +syncytium formation +terminal button organization +translational initiation +transmembrane transport +transposition +vesicle targeting +biological_processsingle-organism processsingle-organism developmental processagingage-dependent behavioral declineage-dependent general metabolic decline +cell aging [GO:0007569] (65 genes, 89 annotations)cellular senescence +chronological cell aging +negative regulation of cell aging +nucleolar fragmentation +positive regulation of cell aging +progressive alteration of chromatin involved in cell aging +regulation of cell aging +replicative cell aging +replicative senescencefruit ripening +multicellular organismal aging +organ senescence +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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