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Gene Ontology Browser
Term Detail
GO term:cell aging
Synonym: cell ageing
GO id:GO:0007569
Definition:An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


obsolete Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-aascospore release from ascus +
                                        is-acell aging [GO:0007569] (80 genes, 109 annotations)
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence +
                                        is-acell dedifferentiation +
                                        is-acell development +
                                        is-acell differentiation +
                                        is-acell fate commitment +
                                        is-acell fate determination +
                                        is-acell fate specification +
                                        is-acell maturation +
                                        is-acellular component morphogenesis +
                                        is-acentrosomal and pronuclear rotation
                                        is-acreation of an inductive signal +
                                        is-adonor selection +
                                        is-ainitiation of movement involved in cerebral cortex radial glia guided migration +
                                        is-aplant-type spore development +
                                        is-aprogrammed cell death involved in cell development +
                                        is-astomatal lineage progression +


obsolete Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-aaging
                                        part-ofage-dependent general metabolic decline +
                                        is-acell aging [GO:0007569] (80 genes, 109 annotations)
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence +
                                        is-afruit ripening +
                                        part-ofmodulation of age-related behavioral decline
                                        is-amulticellular organism aging +
                                        is-aorgan senescence +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-aascospore release from ascus +
                                        is-acell aging [GO:0007569] (80 genes, 109 annotations)
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence +
                                        is-acell dedifferentiation +
                                        is-acell development +
                                        is-acell differentiation +
                                        is-acell fate commitment +
                                        is-acell fate determination +
                                        is-acell fate specification +
                                        is-acell maturation +
                                        is-acellular component morphogenesis +
                                        is-acentrosomal and pronuclear rotation
                                        is-acreation of an inductive signal +
                                        is-adonor selection +
                                        is-ainitiation of movement involved in cerebral cortex radial glia guided migration +
                                        is-aplant-type spore development +
                                        is-aprogrammed cell death involved in cell development +
                                        is-astomatal lineage progression +


obsolete Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-aaging
                                        part-ofage-dependent general metabolic decline +
                                        is-acell aging [GO:0007569] (80 genes, 109 annotations)
                                                is-acellular senescence +
                                                is-achronological cell aging +
                                                negatively-regulatesnegative regulation of cell aging +
                                                part-ofnucleolar fragmentation +
                                                positively-regulatespositive regulation of cell aging +
                                                part-ofprogressive alteration of chromatin involved in cell aging +
                                                regulatesregulation of cell aging +
                                                is-areplicative cell aging +
                                                is-areplicative senescence +
                                        is-afruit ripening +
                                        part-ofmodulation of age-related behavioral decline
                                        is-amulticellular organism aging +
                                        is-aorgan senescence +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory