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Gene Ontology Browser
Term Detail
GO term:Notch receptor processing
Synonym: N receptor processing
GO id:GO:0007220
Definition:The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
Number of paths to term: 5

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-aCAAX-box protein maturation +
                                                is-acellular protein catabolic process +
                                                is-acellular protein modification process +
                                                is-aferredoxin metabolic process +
                                                is-amitochondrial protein processing +
                                                negatively-regulatesnegative regulation of cellular protein metabolic process +
                                                is-aNotch receptor processing [GO:0007220] (7 genes, 8 annotations)
                                                        part-ofNotch receptor processing, ligand-dependent
                                                        part-ofNotch receptor processing, ligand-independent
                                                positively-regulatespositive regulation of cellular protein metabolic process +
                                                part-ofprosthetic group metabolic process +
                                                is-aprotein folding +
                                                is-aprotein repair +
                                                is-aprotein unfolding
                                                regulatesregulation of cellular protein metabolic process +
                                                is-arhodopsin metabolic process +
                                                is-asignal peptide processing +
                                                is-asterol regulatory element binding protein cleavage +
                                                is-atranslation +
                                                is-avacuolar protein processing +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-acellular macromolecule metabolic process
                                        is-acellular protein metabolic process
                                                is-aCAAX-box protein maturation +
                                                is-acellular protein catabolic process +
                                                is-acellular protein modification process +
                                                is-aferredoxin metabolic process +
                                                is-amitochondrial protein processing +
                                                negatively-regulatesnegative regulation of cellular protein metabolic process +
                                                is-aNotch receptor processing [GO:0007220] (7 genes, 8 annotations)
                                                        part-ofNotch receptor processing, ligand-dependent
                                                        part-ofNotch receptor processing, ligand-independent
                                                positively-regulatespositive regulation of cellular protein metabolic process +
                                                part-ofprosthetic group metabolic process +
                                                is-aprotein folding +
                                                is-aprotein repair +
                                                is-aprotein unfolding
                                                regulatesregulation of cellular protein metabolic process +
                                                is-arhodopsin metabolic process +
                                                is-asignal peptide processing +
                                                is-asterol regulatory element binding protein cleavage +
                                                is-atranslation +
                                                is-avacuolar protein processing +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-acellular macromolecule metabolic process
                                                is-acellular protein metabolic process
                                                        is-aCAAX-box protein maturation +
                                                        is-acellular protein catabolic process +
                                                        is-acellular protein modification process +
                                                        is-aferredoxin metabolic process +
                                                        is-amitochondrial protein processing +
                                                        negatively-regulatesnegative regulation of cellular protein metabolic process +
                                                        is-aNotch receptor processing [GO:0007220] (7 genes, 8 annotations)
                                                                part-ofNotch receptor processing, ligand-dependent
                                                                part-ofNotch receptor processing, ligand-independent
                                                        positively-regulatespositive regulation of cellular protein metabolic process +
                                                        part-ofprosthetic group metabolic process +
                                                        is-aprotein folding +
                                                        is-aprotein repair +
                                                        is-aprotein unfolding
                                                        regulatesregulation of cellular protein metabolic process +
                                                        is-arhodopsin metabolic process +
                                                        is-asignal peptide processing +
                                                        is-asterol regulatory element binding protein cleavage +
                                                        is-atranslation +
                                                        is-avacuolar protein processing +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-acellular protein metabolic process
                                                        is-aCAAX-box protein maturation +
                                                        is-acellular protein catabolic process +
                                                        is-acellular protein modification process +
                                                        is-aferredoxin metabolic process +
                                                        is-amitochondrial protein processing +
                                                        negatively-regulatesnegative regulation of cellular protein metabolic process +
                                                        is-aNotch receptor processing [GO:0007220] (7 genes, 8 annotations)
                                                                part-ofNotch receptor processing, ligand-dependent
                                                                part-ofNotch receptor processing, ligand-independent
                                                        positively-regulatespositive regulation of cellular protein metabolic process +
                                                        part-ofprosthetic group metabolic process +
                                                        is-aprotein folding +
                                                        is-aprotein repair +
                                                        is-aprotein unfolding
                                                        regulatesregulation of cellular protein metabolic process +
                                                        is-arhodopsin metabolic process +
                                                        is-asignal peptide processing +
                                                        is-asterol regulatory element binding protein cleavage +
                                                        is-atranslation +
                                                        is-avacuolar protein processing +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-acellular protein metabolic process
                                                is-aCAAX-box protein maturation +
                                                is-acellular protein catabolic process +
                                                is-acellular protein modification process +
                                                is-aferredoxin metabolic process +
                                                is-amitochondrial protein processing +
                                                negatively-regulatesnegative regulation of cellular protein metabolic process +
                                                is-aNotch receptor processing [GO:0007220] (7 genes, 8 annotations)
                                                        part-ofNotch receptor processing, ligand-dependent
                                                        part-ofNotch receptor processing, ligand-independent
                                                positively-regulatespositive regulation of cellular protein metabolic process +
                                                part-ofprosthetic group metabolic process +
                                                is-aprotein folding +
                                                is-aprotein repair +
                                                is-aprotein unfolding
                                                regulatesregulation of cellular protein metabolic process +
                                                is-arhodopsin metabolic process +
                                                is-asignal peptide processing +
                                                is-asterol regulatory element binding protein cleavage +
                                                is-atranslation +
                                                is-avacuolar protein processing +


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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory