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Term Detail
GO term:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
Synonym: GPCR signaling pathway via activation of guanylate cyclase activity
Synonym: GPCR signaling pathway via cGMP second messenger
Synonym: G protein signaling, coupled to cGMP nucleotide second messenger
Synonym: G-protein signaling, coupled to cGMP nucleotide second messenger
Synonym: G protein signalling, coupled to cGMP nucleotide second messenger
Synonym: G-protein signalling, coupled to cGMP nucleotide second messenger
Synonym: guanylate cyclase-activating G-protein coupled receptor signaling pathway
GO id:GO:0007199
Definition:The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                        is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                        is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                        is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                        is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aG-protein coupled receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aG-protein coupled receptor signaling pathway
                                                                is-aG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
                                                                        is-aadenylate cyclase-modulating G-protein coupled receptor signaling pathway +
                                                                        is-aG-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [GO:0007199] (9 genes, 10 annotations)


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory