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Gene Ontology Browser
Term Detail
GO term:complement activation
Synonym: complement activity
Synonym: complement cascade
Synonym: complement response
GO id:GO:0006956
Definition:Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
CommentsThis term was improved by GO_REF:0000022. It was moved.
Number of paths to term: 33

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-apositive regulation of biological process
                                        is-apositive regulation of immune system process
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-apositive regulation of biological process
                                        is-apositive regulation of response to stimulus
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of immune system process
                                        is-apositive regulation of immune system process
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of immune system process
                                        is-aregulation of immune response
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-apositive regulation of response to stimulus
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of response to stimulus
                                        is-aregulation of immune response
                                                is-apositive regulation of immune response
                                                        is-aactivation of immune response
                                                                is-aactivation of innate immune response +
                                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                        is-aactivation of membrane attack complex +
                                                                        is-acomplement activation, alternative pathway +
                                                                        is-acomplement activation, classical pathway +
                                                                        is-acomplement activation, lectin pathway +
                                                                        negatively-regulatesnegative regulation of complement activation +
                                                                        positively-regulatespositive regulation of complement activation +
                                                                        regulatesregulation of complement activation +
                                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aactivation of immune response
                                is-aactivation of innate immune response +
                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                        is-aactivation of membrane attack complex +
                                        is-acomplement activation, alternative pathway +
                                        is-acomplement activation, classical pathway +
                                        is-acomplement activation, lectin pathway +
                                        negatively-regulatesnegative regulation of complement activation +
                                        positively-regulatespositive regulation of complement activation +
                                        regulatesregulation of complement activation +
                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune effector process
                                is-acell activation involved in immune response +
                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                        is-aactivation of membrane attack complex +
                                        is-acomplement activation, alternative pathway +
                                        is-acomplement activation, classical pathway +
                                        is-acomplement activation, lectin pathway +
                                        negatively-regulatesnegative regulation of complement activation +
                                        positively-regulatespositive regulation of complement activation +
                                        regulatesregulation of complement activation +
                                is-adefense response to virus +
                                is-aencapsulation of foreign target +
                                is-agranuloma formation +
                                is-aimmune complex clearance +
                                is-aimmune response-regulating cell surface receptor signaling pathway involved in phagocytosis +
                                is-ainduced systemic resistance, ethylene mediated signaling pathway
                                is-ainduced systemic resistance, jasmonic acid mediated signaling pathway
                                is-aleukocyte degranulation +
                                is-aleukocyte mediated immunity +
                                is-aleukocyte migration involved in immune response +
                                negatively-regulatesnegative regulation of immune effector process +
                                is-aopsonization +
                                positively-regulatespositive regulation of immune effector process +
                                regulatesregulation of immune effector process +
                                is-arespiratory burst involved in defense response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune response
                                is-ahumoral immune response
                                        is-aantimicrobial humoral response +
                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                is-aactivation of membrane attack complex +
                                                is-acomplement activation, alternative pathway +
                                                is-acomplement activation, classical pathway +
                                                is-acomplement activation, lectin pathway +
                                                negatively-regulatesnegative regulation of complement activation +
                                                positively-regulatespositive regulation of complement activation +
                                                regulatesregulation of complement activation +
                                        is-ahemolymph coagulation
                                        is-ahumoral immune response mediated by circulating immunoglobulin +
                                        negatively-regulatesnegative regulation of humoral immune response +
                                        positively-regulatespositive regulation of humoral immune response +
                                        regulatesregulation of humoral immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune response
                                positively-regulatespositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune response
                                regulatesregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        positively-regulatespositive regulation of immune system process
                                is-apositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        regulatesregulation of immune system process
                                is-apositive regulation of immune system process
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        regulatesregulation of immune system process
                                is-aregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-amacromolecule metabolic process
                                        is-aprotein metabolic process
                                                is-aprotein activation cascade
                                                        is-ablood coagulation, common pathway +
                                                        is-ablood coagulation, extrinsic pathway +
                                                        is-ablood coagulation, fibrin clot formation +
                                                        is-ablood coagulation, intrinsic pathway +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-akinin cascade +
                                                        negatively-regulatesnegative regulation of protein activation cascade +
                                                        positively-regulatespositive regulation of protein activation cascade +
                                                        regulatesregulation of protein activation cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aprimary metabolic process
                                is-aprotein metabolic process
                                        is-aprotein activation cascade
                                                is-ablood coagulation, common pathway +
                                                is-ablood coagulation, extrinsic pathway +
                                                is-ablood coagulation, fibrin clot formation +
                                                is-ablood coagulation, intrinsic pathway +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-akinin cascade +
                                                negatively-regulatesnegative regulation of protein activation cascade +
                                                positively-regulatespositive regulation of protein activation cascade +
                                                regulatesregulation of protein activation cascade +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-aprotein activation cascade
                                        is-ablood coagulation, common pathway +
                                        is-ablood coagulation, extrinsic pathway +
                                        is-ablood coagulation, fibrin clot formation +
                                        is-ablood coagulation, intrinsic pathway +
                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                is-aactivation of membrane attack complex +
                                                is-acomplement activation, alternative pathway +
                                                is-acomplement activation, classical pathway +
                                                is-acomplement activation, lectin pathway +
                                                negatively-regulatesnegative regulation of complement activation +
                                                positively-regulatespositive regulation of complement activation +
                                                regulatesregulation of complement activation +
                                        is-akinin cascade +
                                        negatively-regulatesnegative regulation of protein activation cascade +
                                        positively-regulatespositive regulation of protein activation cascade +
                                        regulatesregulation of protein activation cascade +


Gene_Ontology
        is-abiological_process
                positively-regulatespositive regulation of biological process
                        is-apositive regulation of immune system process
                                is-apositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                positively-regulatespositive regulation of biological process
                        is-apositive regulation of response to stimulus
                                is-apositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-apositive regulation of biological process
                                is-apositive regulation of immune system process
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-apositive regulation of biological process
                                is-apositive regulation of response to stimulus
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of immune system process
                                is-apositive regulation of immune system process
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of immune system process
                                is-aregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of response to stimulus
                                is-apositive regulation of response to stimulus
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of response to stimulus
                                is-aregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aimmune response
                                is-ahumoral immune response
                                        is-aantimicrobial humoral response +
                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                is-aactivation of membrane attack complex +
                                                is-acomplement activation, alternative pathway +
                                                is-acomplement activation, classical pathway +
                                                is-acomplement activation, lectin pathway +
                                                negatively-regulatesnegative regulation of complement activation +
                                                positively-regulatespositive regulation of complement activation +
                                                regulatesregulation of complement activation +
                                        is-ahemolymph coagulation
                                        is-ahumoral immune response mediated by circulating immunoglobulin +
                                        negatively-regulatesnegative regulation of humoral immune response +
                                        positively-regulatespositive regulation of humoral immune response +
                                        regulatesregulation of humoral immune response +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aimmune response
                                positively-regulatespositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aimmune response
                                regulatesregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        positively-regulatespositive regulation of response to stimulus
                                is-apositive regulation of immune response
                                        is-aactivation of immune response
                                                is-aactivation of innate immune response +
                                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                        is-aactivation of membrane attack complex +
                                                        is-acomplement activation, alternative pathway +
                                                        is-acomplement activation, classical pathway +
                                                        is-acomplement activation, lectin pathway +
                                                        negatively-regulatesnegative regulation of complement activation +
                                                        positively-regulatespositive regulation of complement activation +
                                                        regulatesregulation of complement activation +
                                                is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aprotein activation cascade
                                is-ablood coagulation, common pathway +
                                is-ablood coagulation, extrinsic pathway +
                                is-ablood coagulation, fibrin clot formation +
                                is-ablood coagulation, intrinsic pathway +
                                is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                        is-aactivation of membrane attack complex +
                                        is-acomplement activation, alternative pathway +
                                        is-acomplement activation, classical pathway +
                                        is-acomplement activation, lectin pathway +
                                        negatively-regulatesnegative regulation of complement activation +
                                        positively-regulatespositive regulation of complement activation +
                                        regulatesregulation of complement activation +
                                is-akinin cascade +
                                negatively-regulatesnegative regulation of protein activation cascade +
                                positively-regulatespositive regulation of protein activation cascade +
                                regulatesregulation of protein activation cascade +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        regulatesregulation of response to stimulus
                                is-apositive regulation of response to stimulus
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        regulatesregulation of response to stimulus
                                is-aregulation of immune response
                                        is-apositive regulation of immune response
                                                is-aactivation of immune response
                                                        is-aactivation of innate immune response +
                                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                                is-aactivation of membrane attack complex +
                                                                is-acomplement activation, alternative pathway +
                                                                is-acomplement activation, classical pathway +
                                                                is-acomplement activation, lectin pathway +
                                                                negatively-regulatesnegative regulation of complement activation +
                                                                positively-regulatespositive regulation of complement activation +
                                                                regulatesregulation of complement activation +
                                                        is-aimmune response-activating signal transduction +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-aprotein activation cascade
                                        is-ablood coagulation, common pathway +
                                        is-ablood coagulation, extrinsic pathway +
                                        is-ablood coagulation, fibrin clot formation +
                                        is-ablood coagulation, intrinsic pathway +
                                        is-acomplement activation [GO:0006956] (47 genes, 89 annotations)
                                                is-aactivation of membrane attack complex +
                                                is-acomplement activation, alternative pathway +
                                                is-acomplement activation, classical pathway +
                                                is-acomplement activation, lectin pathway +
                                                negatively-regulatesnegative regulation of complement activation +
                                                positively-regulatespositive regulation of complement activation +
                                                regulatesregulation of complement activation +
                                        is-akinin cascade +
                                        negatively-regulatesnegative regulation of protein activation cascade +
                                        positively-regulatespositive regulation of protein activation cascade +
                                        regulatesregulation of protein activation cascade +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory