MGI 5.14 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	cholesterol catabolic process
Synonym:	cholesterol breakdown
Synonym:	cholesterol catabolism
Synonym:	cholesterol degradation
GO id:	GO:0006707
Definition:	The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Number of paths to term:	32

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

biological_process

metabolic process

catabolic process

organic substance catabolic process

lipid catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

catabolic process

organic substance catabolic process

organic cyclic compound catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

catabolic process

organic substance catabolic process

organic hydroxy compound catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

catabolic process

single-organism catabolic process

small molecule catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

lipid metabolic process

lipid catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

lipid metabolic process

steroid metabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

organic cyclic compound catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

steroid metabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

steroid metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic cyclic compound metabolic process

steroid metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic hydroxy compound metabolic process

alcohol metabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic hydroxy compound metabolic process

alcohol metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic hydroxy compound metabolic process

alcohol metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic hydroxy compound metabolic process

organic hydroxy compound catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic substance catabolic process

lipid catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic substance catabolic process

organic cyclic compound catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

organic substance metabolic process

organic substance catabolic process

organic hydroxy compound catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

primary metabolic process

lipid metabolic process

lipid catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

primary metabolic process

lipid metabolic process

steroid metabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

primary metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

primary metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

lipid metabolic process

lipid catabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

lipid metabolic process

steroid metabolic process

steroid catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

lipid metabolic process

steroid metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

single-organism catabolic process

small molecule catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

small molecule metabolic process

alcohol metabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

small molecule metabolic process

alcohol metabolic process

sterol metabolic process

cholesterol metabolic process

cholesterol biosynthetic process +

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

cholesterol ester hydrolysis involved in cholesterol transport

negative regulation of cholesterol metabolic process +

peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine

positive regulation of cholesterol metabolic process +

regulation of cholesterol metabolic process +

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

small molecule metabolic process

alcohol metabolic process

sterol metabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Gene_Ontology

biological_process

metabolic process

single-organism metabolic process

small molecule metabolic process

small molecule catabolic process

alcohol catabolic process

sterol catabolic process

cholesterol catabolic process [GO:0006707] (8 genes, 10 annotations)

ecdysone catabolic process

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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