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Gene Ontology Browser
Term Detail
GO term:protein retention in ER lumen
Synonym: maintenance of protein location in ER lumen
GO id:GO:0006621
Definition:The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
Number of paths to term: 19

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-amaintenance of location
                                        is-amaintenance of location in cell
                                                is-amaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological quality
                                is-amaintenance of location
                                        is-amaintenance of protein location
                                                is-amaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-amaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofmaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        part-ofmaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        is-aprotein localization to endoplasmic reticulum
                                                                part-ofmaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-acellular localization
                                part-ofmaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                part-ofmaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        part-ofmaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-acellular macromolecule localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        is-aprotein localization to endoplasmic reticulum
                                                                part-ofmaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-acellular protein localization
                                                part-ofmaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        part-ofmaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        is-acellular protein localization
                                                is-aprotein localization to organelle
                                                        is-aprotein localization to endoplasmic reticulum
                                                                part-ofmaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amacromolecule localization
                                is-aprotein localization
                                        part-ofmaintenance of protein location
                                                is-amaintenance of protein location in cell
                                                        is-amaintenance of protein localization in organelle
                                                                is-amaintenance of protein localization in endoplasmic reticulum
                                                                        is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                        is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amaintenance of location
                                is-amaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-amaintenance of location
                                is-amaintenance of protein location
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-alocalization
                        is-asingle-organism localization
                                is-amaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-amaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism localization
                                is-amaintenance of location in cell
                                        is-amaintenance of protein location in cell
                                                is-amaintenance of protein localization in organelle
                                                        is-amaintenance of protein localization in endoplasmic reticulum
                                                                is-aprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)
                                                                is-aSREBP-SCAP complex retention in endoplasmic reticulum


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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory