| GO term: | protein retention in ER lumen |
| Synonym: | maintenance of protein location in ER lumen |
| GO id: | GO:0006621 |
| Definition: | The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER. |
| Number of paths to term: | 25 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological qualitymaintenance of locationmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processbiological regulationregulation of biological qualitymaintenance of locationmaintenance of protein locationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processcellular processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processcellular processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organellemaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processcellular processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organelleprotein localization to endoplasmic reticulummaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processcellular processsingle-organism cellular processcellular localizationmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processcellular processsingle-organism cellular processmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationcellular localizationcellular macromolecule localizationcellular protein localizationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organellemaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organelleprotein localization to endoplasmic reticulummaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationcellular localizationmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationcellular macromolecule localizationcellular protein localizationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationcellular macromolecule localizationcellular protein localizationprotein localization to organellemaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationcellular macromolecule localizationcellular protein localizationprotein localization to organelleprotein localization to endoplasmic reticulummaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationprotein localizationcellular protein localizationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationprotein localizationcellular protein localizationprotein localization to organellemaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationprotein localizationcellular protein localizationprotein localization to organelleprotein localization to endoplasmic reticulummaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmacromolecule localizationprotein localizationmaintenance of protein locationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmaintenance of locationmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processlocalizationmaintenance of locationmaintenance of protein locationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processsingle-organism processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processsingle-organism processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organellemaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processsingle-organism processsingle-organism cellular processcellular localizationcellular macromolecule localizationcellular protein localizationprotein localization to organelleprotein localization to endoplasmic reticulummaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processsingle-organism processsingle-organism cellular processcellular localizationmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumbiological_processsingle-organism processsingle-organism cellular processmaintenance of location in cellmaintenance of protein location in cellmaintenance of protein localization in organellemaintenance of protein localization in endoplasmic reticulumprotein retention in ER lumen [GO:0006621] (6 genes, 6 annotations)SREBP-SCAP complex retention in endoplasmic reticulumMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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