About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:2-oxoglutarate metabolic process
Synonym: 2-ketoglutarate metabolic process
Synonym: 2-ketoglutarate metabolism
Synonym: 2-oxoglutarate metabolism
Synonym: alpha-ketoglutarate metabolic process
Synonym: alpha-ketoglutarate metabolism
Synonym: alpha-oxoglutarate metabolic process
Synonym: alpha-oxoglutarate metabolism
GO id:GO:0006103
Definition:The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
Number of paths to term: 7

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular metabolic process
                                is-aorganic acid metabolic process
                                        is-aoxoacid metabolic process
                                                is-acarboxylic acid metabolic process
                                                        is-adicarboxylic acid metabolic process
                                                                is-a10-formyltetrahydrofolate metabolic process +
                                                                is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                        is-aacetyl-CoA assimilation pathway
                                                                        is-aglucose catabolic process to mixed acids
                                                                        is-aglutamate catabolic process to 2-oxoglutarate
                                                                        is-aglutamate catabolic process via 2-oxoglutarate
                                                                        is-ahistidine catabolic process to 2-oxoglutarate
                                                                        is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                        is-aproline catabolic process to 2-oxoglutarate
                                                                is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                is-aaldaric acid metabolic process +
                                                                is-aaspartate metabolic process +
                                                                is-achorismate metabolic process +
                                                                is-adiaminopimelate metabolic process +
                                                                is-adicarboxylic acid biosynthetic process +
                                                                is-adicarboxylic acid catabolic process +
                                                                is-adihydrofolate metabolic process +
                                                                is-afolic acid metabolic process +
                                                                is-afumarate metabolic process +
                                                                is-agibberellin 12 metabolic process +
                                                                is-aglutamate metabolic process +
                                                                is-aKdo2-lipid A metabolic process +
                                                                is-amalate metabolic process
                                                                is-aoxalate metabolic process +
                                                                is-aoxaloacetate metabolic process +
                                                                is-aphthalate metabolic process +
                                                                is-aprephenate(2-) metabolic process +
                                                                is-aprotocatechuate catabolic process, ortho-cleavage
                                                                is-aquinolinate metabolic process +
                                                                is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-aorganic acid metabolic process
                                        is-aoxoacid metabolic process
                                                is-acarboxylic acid metabolic process
                                                        is-adicarboxylic acid metabolic process
                                                                is-a10-formyltetrahydrofolate metabolic process +
                                                                is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                        is-aacetyl-CoA assimilation pathway
                                                                        is-aglucose catabolic process to mixed acids
                                                                        is-aglutamate catabolic process to 2-oxoglutarate
                                                                        is-aglutamate catabolic process via 2-oxoglutarate
                                                                        is-ahistidine catabolic process to 2-oxoglutarate
                                                                        is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                        is-aproline catabolic process to 2-oxoglutarate
                                                                is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                is-aaldaric acid metabolic process +
                                                                is-aaspartate metabolic process +
                                                                is-achorismate metabolic process +
                                                                is-adiaminopimelate metabolic process +
                                                                is-adicarboxylic acid biosynthetic process +
                                                                is-adicarboxylic acid catabolic process +
                                                                is-adihydrofolate metabolic process +
                                                                is-afolic acid metabolic process +
                                                                is-afumarate metabolic process +
                                                                is-agibberellin 12 metabolic process +
                                                                is-aglutamate metabolic process +
                                                                is-aKdo2-lipid A metabolic process +
                                                                is-amalate metabolic process
                                                                is-aoxalate metabolic process +
                                                                is-aoxaloacetate metabolic process +
                                                                is-aphthalate metabolic process +
                                                                is-aprephenate(2-) metabolic process +
                                                                is-aprotocatechuate catabolic process, ortho-cleavage
                                                                is-aquinolinate metabolic process +
                                                                is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-acellular metabolic process
                                is-aorganic acid metabolic process
                                        is-aoxoacid metabolic process
                                                is-acarboxylic acid metabolic process
                                                        is-adicarboxylic acid metabolic process
                                                                is-a10-formyltetrahydrofolate metabolic process +
                                                                is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                        is-aacetyl-CoA assimilation pathway
                                                                        is-aglucose catabolic process to mixed acids
                                                                        is-aglutamate catabolic process to 2-oxoglutarate
                                                                        is-aglutamate catabolic process via 2-oxoglutarate
                                                                        is-ahistidine catabolic process to 2-oxoglutarate
                                                                        is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                        is-aproline catabolic process to 2-oxoglutarate
                                                                is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                is-aaldaric acid metabolic process +
                                                                is-aaspartate metabolic process +
                                                                is-achorismate metabolic process +
                                                                is-adiaminopimelate metabolic process +
                                                                is-adicarboxylic acid biosynthetic process +
                                                                is-adicarboxylic acid catabolic process +
                                                                is-adihydrofolate metabolic process +
                                                                is-afolic acid metabolic process +
                                                                is-afumarate metabolic process +
                                                                is-agibberellin 12 metabolic process +
                                                                is-aglutamate metabolic process +
                                                                is-aKdo2-lipid A metabolic process +
                                                                is-amalate metabolic process
                                                                is-aoxalate metabolic process +
                                                                is-aoxaloacetate metabolic process +
                                                                is-aphthalate metabolic process +
                                                                is-aprephenate(2-) metabolic process +
                                                                is-aprotocatechuate catabolic process, ortho-cleavage
                                                                is-aquinolinate metabolic process +
                                                                is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-aorganic substance metabolic process
                                is-aorganic acid metabolic process
                                        is-aoxoacid metabolic process
                                                is-acarboxylic acid metabolic process
                                                        is-adicarboxylic acid metabolic process
                                                                is-a10-formyltetrahydrofolate metabolic process +
                                                                is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                        is-aacetyl-CoA assimilation pathway
                                                                        is-aglucose catabolic process to mixed acids
                                                                        is-aglutamate catabolic process to 2-oxoglutarate
                                                                        is-aglutamate catabolic process via 2-oxoglutarate
                                                                        is-ahistidine catabolic process to 2-oxoglutarate
                                                                        is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                        is-aproline catabolic process to 2-oxoglutarate
                                                                is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                is-aaldaric acid metabolic process +
                                                                is-aaspartate metabolic process +
                                                                is-achorismate metabolic process +
                                                                is-adiaminopimelate metabolic process +
                                                                is-adicarboxylic acid biosynthetic process +
                                                                is-adicarboxylic acid catabolic process +
                                                                is-adihydrofolate metabolic process +
                                                                is-afolic acid metabolic process +
                                                                is-afumarate metabolic process +
                                                                is-agibberellin 12 metabolic process +
                                                                is-aglutamate metabolic process +
                                                                is-aKdo2-lipid A metabolic process +
                                                                is-amalate metabolic process
                                                                is-aoxalate metabolic process +
                                                                is-aoxaloacetate metabolic process +
                                                                is-aphthalate metabolic process +
                                                                is-aprephenate(2-) metabolic process +
                                                                is-aprotocatechuate catabolic process, ortho-cleavage
                                                                is-aquinolinate metabolic process +
                                                                is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-ametabolic process
                        is-asingle-organism metabolic process
                                is-asmall molecule metabolic process
                                        is-aorganic acid metabolic process
                                                is-aoxoacid metabolic process
                                                        is-acarboxylic acid metabolic process
                                                                is-adicarboxylic acid metabolic process
                                                                        is-a10-formyltetrahydrofolate metabolic process +
                                                                        is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                                is-aacetyl-CoA assimilation pathway
                                                                                is-aglucose catabolic process to mixed acids
                                                                                is-aglutamate catabolic process to 2-oxoglutarate
                                                                                is-aglutamate catabolic process via 2-oxoglutarate
                                                                                is-ahistidine catabolic process to 2-oxoglutarate
                                                                                is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                                is-aproline catabolic process to 2-oxoglutarate
                                                                        is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                        is-aaldaric acid metabolic process +
                                                                        is-aaspartate metabolic process +
                                                                        is-achorismate metabolic process +
                                                                        is-adiaminopimelate metabolic process +
                                                                        is-adicarboxylic acid biosynthetic process +
                                                                        is-adicarboxylic acid catabolic process +
                                                                        is-adihydrofolate metabolic process +
                                                                        is-afolic acid metabolic process +
                                                                        is-afumarate metabolic process +
                                                                        is-agibberellin 12 metabolic process +
                                                                        is-aglutamate metabolic process +
                                                                        is-aKdo2-lipid A metabolic process +
                                                                        is-amalate metabolic process
                                                                        is-aoxalate metabolic process +
                                                                        is-aoxaloacetate metabolic process +
                                                                        is-aphthalate metabolic process +
                                                                        is-aprephenate(2-) metabolic process +
                                                                        is-aprotocatechuate catabolic process, ortho-cleavage
                                                                        is-aquinolinate metabolic process +
                                                                        is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-aorganic acid metabolic process
                                        is-aoxoacid metabolic process
                                                is-acarboxylic acid metabolic process
                                                        is-adicarboxylic acid metabolic process
                                                                is-a10-formyltetrahydrofolate metabolic process +
                                                                is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                        is-aacetyl-CoA assimilation pathway
                                                                        is-aglucose catabolic process to mixed acids
                                                                        is-aglutamate catabolic process to 2-oxoglutarate
                                                                        is-aglutamate catabolic process via 2-oxoglutarate
                                                                        is-ahistidine catabolic process to 2-oxoglutarate
                                                                        is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                        is-aproline catabolic process to 2-oxoglutarate
                                                                is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                is-aaldaric acid metabolic process +
                                                                is-aaspartate metabolic process +
                                                                is-achorismate metabolic process +
                                                                is-adiaminopimelate metabolic process +
                                                                is-adicarboxylic acid biosynthetic process +
                                                                is-adicarboxylic acid catabolic process +
                                                                is-adihydrofolate metabolic process +
                                                                is-afolic acid metabolic process +
                                                                is-afumarate metabolic process +
                                                                is-agibberellin 12 metabolic process +
                                                                is-aglutamate metabolic process +
                                                                is-aKdo2-lipid A metabolic process +
                                                                is-amalate metabolic process
                                                                is-aoxalate metabolic process +
                                                                is-aoxaloacetate metabolic process +
                                                                is-aphthalate metabolic process +
                                                                is-aprephenate(2-) metabolic process +
                                                                is-aprotocatechuate catabolic process, ortho-cleavage
                                                                is-aquinolinate metabolic process +
                                                                is-asuccinate metabolic process +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism metabolic process
                                is-asmall molecule metabolic process
                                        is-aorganic acid metabolic process
                                                is-aoxoacid metabolic process
                                                        is-acarboxylic acid metabolic process
                                                                is-adicarboxylic acid metabolic process
                                                                        is-a10-formyltetrahydrofolate metabolic process +
                                                                        is-a2-oxoglutarate metabolic process [GO:0006103] (16 genes, 17 annotations)
                                                                                is-aacetyl-CoA assimilation pathway
                                                                                is-aglucose catabolic process to mixed acids
                                                                                is-aglutamate catabolic process to 2-oxoglutarate
                                                                                is-aglutamate catabolic process via 2-oxoglutarate
                                                                                is-ahistidine catabolic process to 2-oxoglutarate
                                                                                is-aL-arabinose catabolic process to 2-oxoglutarate
                                                                                is-aproline catabolic process to 2-oxoglutarate
                                                                        is-a5,6,7,8-tetrahydromethanopterin metabolic process +
                                                                        is-aaldaric acid metabolic process +
                                                                        is-aaspartate metabolic process +
                                                                        is-achorismate metabolic process +
                                                                        is-adiaminopimelate metabolic process +
                                                                        is-adicarboxylic acid biosynthetic process +
                                                                        is-adicarboxylic acid catabolic process +
                                                                        is-adihydrofolate metabolic process +
                                                                        is-afolic acid metabolic process +
                                                                        is-afumarate metabolic process +
                                                                        is-agibberellin 12 metabolic process +
                                                                        is-aglutamate metabolic process +
                                                                        is-aKdo2-lipid A metabolic process +
                                                                        is-amalate metabolic process
                                                                        is-aoxalate metabolic process +
                                                                        is-aoxaloacetate metabolic process +
                                                                        is-aphthalate metabolic process +
                                                                        is-aprephenate(2-) metabolic process +
                                                                        is-aprotocatechuate catabolic process, ortho-cleavage
                                                                        is-aquinolinate metabolic process +
                                                                        is-asuccinate metabolic process +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory