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Gene Ontology Browser
Term Detail
GO term:extracellular ligand-gated ion channel activity
GO id:GO:0005230
Definition:Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
Number of paths to term: 6

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity +
                                                                is-acalcium-release channel activity +
                                                                is-acyclic nucleotide-gated ion channel activity +
                                                                is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity +
                                                                is-ahistamine-gated chloride channel activity
                                                                is-aintracellular ligand-gated ion channel activity +
                                                                is-ainward rectifier potassium channel activity +
                                                                is-aligand-gated sodium channel activity +
                                                                is-astore-operated calcium channel activity
                                                                is-atransmitter-gated ion channel activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-asubstrate-specific transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity +
                                                                is-acalcium-release channel activity +
                                                                is-acyclic nucleotide-gated ion channel activity +
                                                                is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity +
                                                                is-ahistamine-gated chloride channel activity
                                                                is-aintracellular ligand-gated ion channel activity +
                                                                is-ainward rectifier potassium channel activity +
                                                                is-aligand-gated sodium channel activity +
                                                                is-astore-operated calcium channel activity
                                                                is-atransmitter-gated ion channel activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-agated channel activity
                                                        is-aligand-gated channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aATP-gated ion channel activity +
                                                                        is-acalcium-release channel activity +
                                                                        is-acyclic nucleotide-gated ion channel activity +
                                                                        is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                                is-aextracellular ammonia-gated ion channel activity
                                                                                is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                                is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                                is-aionotropic glutamate receptor activity +
                                                                        is-ahistamine-gated chloride channel activity
                                                                        is-aintracellular ligand-gated ion channel activity +
                                                                        is-ainward rectifier potassium channel activity +
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-astore-operated calcium channel activity
                                                                        is-atransmitter-gated ion channel activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-apassive transmembrane transporter activity
                                        is-achannel activity
                                                is-asubstrate-specific channel activity
                                                        is-aion channel activity
                                                                is-aligand-gated ion channel activity
                                                                        is-aATP-gated ion channel activity +
                                                                        is-acalcium-release channel activity +
                                                                        is-acyclic nucleotide-gated ion channel activity +
                                                                        is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                                is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                                is-aextracellular ammonia-gated ion channel activity
                                                                                is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                                is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                                is-aionotropic glutamate receptor activity +
                                                                        is-ahistamine-gated chloride channel activity
                                                                        is-aintracellular ligand-gated ion channel activity +
                                                                        is-ainward rectifier potassium channel activity +
                                                                        is-aligand-gated sodium channel activity +
                                                                        is-astore-operated calcium channel activity
                                                                        is-atransmitter-gated ion channel activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-aion transmembrane transporter activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity +
                                                                is-acalcium-release channel activity +
                                                                is-acyclic nucleotide-gated ion channel activity +
                                                                is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity +
                                                                is-ahistamine-gated chloride channel activity
                                                                is-aintracellular ligand-gated ion channel activity +
                                                                is-ainward rectifier potassium channel activity +
                                                                is-aligand-gated sodium channel activity +
                                                                is-astore-operated calcium channel activity
                                                                is-atransmitter-gated ion channel activity +


Gene_Ontology
        is-amolecular_function
                is-atransporter activity
                        is-atransmembrane transporter activity
                                is-asubstrate-specific transmembrane transporter activity
                                        is-asubstrate-specific channel activity
                                                is-aion channel activity
                                                        is-aligand-gated ion channel activity
                                                                is-aATP-gated ion channel activity +
                                                                is-acalcium-release channel activity +
                                                                is-acyclic nucleotide-gated ion channel activity +
                                                                is-aextracellular ligand-gated ion channel activity [GO:0005230] (67 genes, 196 annotations)
                                                                        is-aexcitatory extracellular ligand-gated ion channel activity +
                                                                        is-aextracellular ammonia-gated ion channel activity
                                                                        is-aextracellular phenylacetaldehyde-gated ion channel activity
                                                                        is-ainhibitory extracellular ligand-gated ion channel activity +
                                                                        is-aionotropic glutamate receptor activity +
                                                                is-ahistamine-gated chloride channel activity
                                                                is-aintracellular ligand-gated ion channel activity +
                                                                is-ainward rectifier potassium channel activity +
                                                                is-aligand-gated sodium channel activity +
                                                                is-astore-operated calcium channel activity
                                                                is-atransmitter-gated ion channel activity +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory