| GO term: | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
| Synonym: | inositol-1,4,5-trisphosphate receptor activity |
| Synonym: | InsP3 receptor |
| Synonym: | IP3 receptor activity |
| GO id: | GO:0005220 |
| Definition: | Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts. |
| Number of paths to term: | 31 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionmolecular transducer activitysignal transducer activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)leucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity +neurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity +U-plasminogen activator receptor activitymolecular_functionreceptor activitysignaling receptor activityadvanced glycation end-product receptor activityaryl hydrocarbon receptor activitycoreceptor activity +corticotropin-releasing hormone receptor activitydiuretic hormone receptor activityhigh molecular weight B cell growth factor receptor activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)leucokinin receptor activityligand-activated RNA polymerase II transcription factor binding transcription factor activity +ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity +neurotransmitter receptor activity +neurotrophin receptor activity +pattern recognition receptor activity +peptide receptor activity +phorbol ester receptor activity +phosphorelay sensor kinase activityphotoreceptor activity +steroid hormone receptor activity +thrombospondin receptor activitytransmembrane signaling receptor activity +U-plasminogen activator receptor activitymolecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activityinorganic cation transmembrane transporter activitydivalent inorganic cation transmembrane transporter activitycalcium ion transmembrane transporter activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitymetal ion transmembrane transporter activitycalcium ion transmembrane transporter activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitysubstrate-specific transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityion gated channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitygated channel activityligand-gated channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitypassive transmembrane transporter activitychannel activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activityinorganic cation transmembrane transporter activitydivalent inorganic cation transmembrane transporter activitycalcium ion transmembrane transporter activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activitycation transmembrane transporter activitymetal ion transmembrane transporter activitycalcium ion transmembrane transporter activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activityion transmembrane transporter activityion gated channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activitycation channel activitycalcium channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activitycalcium-release channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular ligand-gated calcium channel activity +molecular_functiontransporter activitytransmembrane transporter activitysubstrate-specific transmembrane transporter activitysubstrate-specific channel activityion channel activityligand-gated ion channel activityintracellular ligand-gated ion channel activityATP-binding and phosphorylation-dependent chloride channel activityinositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0005220] (3 genes, 7 annotations)intracellular cyclic nucleotide activated cation channel activity +intracellular ligand-gated calcium channel activity +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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