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Gene Ontology Browser
Term Detail
GO term:ARF guanyl-nucleotide exchange factor activity
GO id:GO:0005086
Definition:Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

                is-amolecular function regulator
                        is-aguanyl-nucleotide exchange factor activity
                                is-aARF guanyl-nucleotide exchange factor activity [GO:0005086] (20 genes, 23 annotations)
                                is-acyclic nucleotide-dependent guanyl-nucleotide exchange factor activity
                                is-aRas guanyl-nucleotide exchange factor activity +
                                is-aSar guanyl-nucleotide exchange factor activity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.08
The Jackson Laboratory