| GO term: | ARF guanyl-nucleotide exchange factor activity |
| GO id: | GO:0005086 |
| Definition: | Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionenzyme regulator activitynucleoside-triphosphatase regulator activityGTPase regulator activityguanyl-nucleotide exchange factor activityARF guanyl-nucleotide exchange factor activity [GO:0005086] (17 genes, 18 annotations)cyclic nucleotide-dependent guanyl-nucleotide exchange factor activityRas guanyl-nucleotide exchange factor activity +Sar guanyl-nucleotide exchange factor activitymolecular_functionenzyme regulator activitynucleoside-triphosphatase regulator activityGTPase regulator activitysmall GTPase regulator activityARF GTPase activator activityARF guanyl-nucleotide exchange factor activity [GO:0005086] (17 genes, 18 annotations)GDP-dissociation inhibitor activity +guanyl-nucleotide exchange factor adaptor activityRas GTPase activator activity +Ras guanyl-nucleotide exchange factor activity +Sar GTPase activator activitySar guanyl-nucleotide exchange factor activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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