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Gene Ontology Browser
Term Detail
GO term:tumor necrosis factor-activated receptor activity
Synonym: NGF/TNF (6 C-domain) receptor activity
Synonym: TNF receptor activity
Synonym: TNF receptor activity, type I
Synonym: TNF receptor activity, type II
Synonym: tumor necrosis factor receptor activity
Synonym: tumor necrosis factor receptor activity, type I
Synonym: tumor necrosis factor receptor activity, type II
GO id:GO:0005031
Definition:Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-adeath receptor activity
                                                        is-aTRAIL receptor activity
                                                        is-atumor necrosis factor-activated receptor activity [GO:0005031] (5 genes, 9 annotations)
                                                                is-aTNFSF11 receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-adeath receptor activity
                                                is-aTRAIL receptor activity
                                                is-atumor necrosis factor-activated receptor activity [GO:0005031] (5 genes, 9 annotations)
                                                        is-aTNFSF11 receptor activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory