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Term Detail
GO term:interleukin-1 receptor activity
Synonym: IL-1R
Synonym: IL-1 receptor activity
GO id:GO:0004908
Definition:Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-amolecular transducer activity
                        is-asignal transducer activity
                                is-asignaling receptor activity
                                        is-atransmembrane signaling receptor activity
                                                is-acytokine receptor activity
                                                        is-achemokine receptor activity +
                                                        is-aciliary neurotrophic factor receptor activity +
                                                        is-aerythropoietin receptor activity
                                                        is-aglial cell-derived neurotrophic factor receptor activity
                                                        is-agranulocyte colony-stimulating factor receptor activity
                                                        is-agranulocyte macrophage colony-stimulating factor receptor activity
                                                        is-agrowth hormone receptor activity
                                                        is-ahigh mobility group box 1 receptor activity
                                                        is-ainterferon receptor activity +
                                                        is-ainterleukin-1 receptor activity [GO:0004908] (7 genes, 11 annotations)
                                                                is-ainterleukin-1, Type I, activating receptor activity
                                                                is-ainterleukin-1, Type II, blocking receptor activity
                                                        is-ainterleukin-10 receptor activity
                                                        is-ainterleukin-11 receptor activity
                                                        is-ainterleukin-12 receptor activity
                                                        is-ainterleukin-13 receptor activity
                                                        is-ainterleukin-14 receptor activity
                                                        is-ainterleukin-15 receptor activity
                                                        is-ainterleukin-16 receptor activity
                                                        is-ainterleukin-17 receptor activity +
                                                        is-ainterleukin-18 receptor activity
                                                        is-ainterleukin-19 receptor activity
                                                        is-ainterleukin-2 receptor activity
                                                        is-ainterleukin-20 receptor activity
                                                        is-ainterleukin-21 receptor activity
                                                        is-ainterleukin-22 receptor activity
                                                        is-ainterleukin-23 receptor activity
                                                        is-ainterleukin-24 receptor activity
                                                        is-ainterleukin-25 receptor activity
                                                        is-ainterleukin-26 receptor activity
                                                        is-ainterleukin-27 receptor activity
                                                        is-ainterleukin-3 receptor activity
                                                        is-ainterleukin-33 receptor activity
                                                        is-ainterleukin-35 receptor activity
                                                        is-ainterleukin-4 receptor activity
                                                        is-ainterleukin-5 receptor activity
                                                        is-ainterleukin-6 receptor activity
                                                        is-ainterleukin-7 receptor activity
                                                        is-ainterleukin-9 receptor activity
                                                        is-aleptin receptor activity
                                                        is-aoncostatin-M receptor activity
                                                        is-aprolactin receptor activity
                                                        is-athrombopoietin receptor activity


Gene_Ontology
        is-amolecular_function
                is-areceptor activity
                        is-asignaling receptor activity
                                is-atransmembrane signaling receptor activity
                                        is-acytokine receptor activity
                                                is-achemokine receptor activity +
                                                is-aciliary neurotrophic factor receptor activity +
                                                is-aerythropoietin receptor activity
                                                is-aglial cell-derived neurotrophic factor receptor activity
                                                is-agranulocyte colony-stimulating factor receptor activity
                                                is-agranulocyte macrophage colony-stimulating factor receptor activity
                                                is-agrowth hormone receptor activity
                                                is-ahigh mobility group box 1 receptor activity
                                                is-ainterferon receptor activity +
                                                is-ainterleukin-1 receptor activity [GO:0004908] (7 genes, 11 annotations)
                                                        is-ainterleukin-1, Type I, activating receptor activity
                                                        is-ainterleukin-1, Type II, blocking receptor activity
                                                is-ainterleukin-10 receptor activity
                                                is-ainterleukin-11 receptor activity
                                                is-ainterleukin-12 receptor activity
                                                is-ainterleukin-13 receptor activity
                                                is-ainterleukin-14 receptor activity
                                                is-ainterleukin-15 receptor activity
                                                is-ainterleukin-16 receptor activity
                                                is-ainterleukin-17 receptor activity +
                                                is-ainterleukin-18 receptor activity
                                                is-ainterleukin-19 receptor activity
                                                is-ainterleukin-2 receptor activity
                                                is-ainterleukin-20 receptor activity
                                                is-ainterleukin-21 receptor activity
                                                is-ainterleukin-22 receptor activity
                                                is-ainterleukin-23 receptor activity
                                                is-ainterleukin-24 receptor activity
                                                is-ainterleukin-25 receptor activity
                                                is-ainterleukin-26 receptor activity
                                                is-ainterleukin-27 receptor activity
                                                is-ainterleukin-3 receptor activity
                                                is-ainterleukin-33 receptor activity
                                                is-ainterleukin-35 receptor activity
                                                is-ainterleukin-4 receptor activity
                                                is-ainterleukin-5 receptor activity
                                                is-ainterleukin-6 receptor activity
                                                is-ainterleukin-7 receptor activity
                                                is-ainterleukin-9 receptor activity
                                                is-aleptin receptor activity
                                                is-aoncostatin-M receptor activity
                                                is-aprolactin receptor activity
                                                is-athrombopoietin receptor activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory