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Gene Ontology Browser
Term Detail
GO term:aminoacyl-tRNA ligase activity
Synonym: aminoacyl-tRNA synthetase activity
Synonym: aminoacyl-tRNA synthetase auxiliary protein activity
GO id:GO:0004812
Definition:Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
CommentsNote that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aligase activity
                                is-aligase activity, forming carbon-oxygen bonds
                                        is-aligase activity, forming aminoacyl-tRNA and related compounds
                                                is-aaminoacyl-tRNA ligase activity [GO:0004812] (42 genes, 90 annotations)
                                                        is-aalanine-tRNA ligase activity
                                                        is-aarginine-tRNA ligase activity
                                                        is-aasparagine-tRNA ligase activity
                                                        is-aaspartate-tRNA ligase activity
                                                        is-aaspartate-tRNA(Asn) ligase activity
                                                        is-acysteine-tRNA ligase activity
                                                        is-aglutamate-tRNA ligase activity
                                                        is-aglutamate-tRNA(Gln) ligase activity
                                                        is-aglutamine-tRNA ligase activity
                                                        is-aglycine-tRNA ligase activity
                                                        is-ahistidine-tRNA ligase activity
                                                        is-aisoleucine-tRNA ligase activity
                                                        is-aleucine-tRNA ligase activity
                                                        is-alysine-tRNA ligase activity
                                                        is-alysine-tRNA(Pyl) ligase activity
                                                        is-amethionine-tRNA ligase activity
                                                        is-aphenylalanine-tRNA ligase activity
                                                        is-aphosphoserine-tRNA(Cys) ligase activity
                                                        is-aproline-tRNA ligase activity
                                                        is-apyrrolysyl-tRNA synthetase activity
                                                        is-aselenocysteine-tRNA ligase activity
                                                        is-aselenomethionine-tRNA ligase activity
                                                        is-aserine-tRNA ligase activity
                                                        is-athreonine-tRNA ligase activity
                                                        is-atryptophan-tRNA ligase activity
                                                        is-atyrosine-tRNA ligase activity
                                                        is-avaline-tRNA ligase activity
                                                is-aD-alanine-poly(phosphoribitol) ligase activity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory