| GO term: | ribonuclease H activity |
| Synonym: | calf thymus ribonuclease H activity |
| Synonym: | endoribonuclease0 H activity |
| Synonym: | endoribonuclease H |
| Synonym: | endoribonuclease H (calf thymus) |
| Synonym: | hybridase activity |
| Synonym: | hybridase (ribonuclease H) |
| Synonym: | hybrid nuclease activity |
| Synonym: | hybrid ribonuclease activity |
| Synonym: | ribonuclease H1 activity |
| Synonym: | ribonuclease H2 activity |
| Synonym: | ribonuclease H3 activity |
| Synonym: | RNA*DNA hybrid ribonucleotidohydrolase activity |
| Synonym: | RNase H1 activity |
| Synonym: | RNase H2 activity |
| Synonym: | RNase H3 activity |
| Synonym: | RNase H activity |
| GO id: | GO:0004523 |
| Definition: | Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. |
| Comments | Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species. |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityhydrolase activityhydrolase activity, acting on ester bondsnuclease activityendonuclease activityendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersendoribonuclease activity, producing 5'-phosphomonoesters3'-tRNA processing endoribonuclease activityapurinic/apyrimidinic endoribonuclease activityendoribonuclease activity, cleaving siRNA-paired mRNAribonuclease [poly-(U)-specific] activityribonuclease H activity [GO:0004523] (3 genes, 4 annotations)ribonuclease III activity +ribonuclease IV activityribonuclease IX activityribonuclease M5 activityribonuclease P activityribonuclease P4 activityRNA lariat debranching enzyme activitymolecular_functioncatalytic activityhydrolase activityhydrolase activity, acting on ester bondsnuclease activityendonuclease activityendoribonuclease activityendoribonuclease activity, producing 5'-phosphomonoesters3'-tRNA processing endoribonuclease activityapurinic/apyrimidinic endoribonuclease activityendoribonuclease activity, cleaving siRNA-paired mRNAribonuclease [poly-(U)-specific] activityribonuclease H activity [GO:0004523] (3 genes, 4 annotations)ribonuclease III activity +ribonuclease IV activityribonuclease IX activityribonuclease M5 activityribonuclease P activityribonuclease P4 activityRNA lariat debranching enzyme activitymolecular_functioncatalytic activityhydrolase activityhydrolase activity, acting on ester bondsnuclease activityribonuclease activityendoribonuclease activityendoribonuclease activity, producing 5'-phosphomonoesters3'-tRNA processing endoribonuclease activityapurinic/apyrimidinic endoribonuclease activityendoribonuclease activity, cleaving siRNA-paired mRNAribonuclease [poly-(U)-specific] activityribonuclease H activity [GO:0004523] (3 genes, 4 annotations)ribonuclease III activity +ribonuclease IV activityribonuclease IX activityribonuclease M5 activityribonuclease P activityribonuclease P4 activityRNA lariat debranching enzyme activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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