MGI 5.13 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	nitric-oxide synthase activity
Synonym:	endothelium-derived relaxation factor-forming enzyme activity
Synonym:	endothelium-derived relaxing factor synthase activity
Synonym:	L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity
Synonym:	NADPH-diaphorase activity
Synonym:	nitric oxide synthase activity
Synonym:	nitric oxide synthetase activity
Synonym:	nitric-oxide synthetase activity
Synonym:	NO synthase activity
GO id:	GO:0004517
Definition:	Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
Number of paths to term:	2

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

molecular_function

catalytic activity

oxidoreductase activity

monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

(+)-abscisic acid 8'-hydroxylase activity

(+)-menthofuran synthase activity

(-)-menthol monooxygenase activity

(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity

1-hydroxy-2-naphthoate hydroxylase activity

1-hydroxy-2-oxolimonene 1,2-monooxygenase activity

1-methylnaphthalene hydroxylase activity

2,4-dichlorophenol 6-monooxygenase activity

2,6-dihydroxypyridine 3-monooxygenase activity

2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity

2-hydroxy-phenylacetate hydroxylase activity

2-hydroxybiphenyl 3-monooxygenase activity

2-hydroxycyclohexanone 2-monooxygenase activity

2-hydroxyisoflavanone synthase activity

2-hydroxyquinoline 8-monooxygenase activity

2-methylnaphthalene hydroxylase activity

2-nitrophenol 2-monooxygenase activity

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity

2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity

24-hydroxycholesterol 7alpha-hydroxylase activity

25-hydroxycholesterol 7alpha-hydroxylase activity

27-hydroxycholesterol 7-alpha-monooxygenase activity

3,5-xylenol methylhydroxylase activity

3,9-dihydroxypterocarpan 6a-monooxygenase activity

3-(3-hydroxyphenyl)propionate hydroxylase activity

3-HSA hydroxylase activity

3-hydroxybenzoate 4-monooxygenase activity

3-hydroxybenzoate 6-monooxygenase activity

3-hydroxyindolin-2-one monooxygenase activity

3-hydroxyphenylacetate 6-hydroxylase activity

3-ketosteroid 9-alpha-monooxygenase activity

3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity

4'-methoxyisoflavone 2'-hydroxylase activity

4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity

4-aminobenzoate 1-monooxygenase activity

4-chlorobenzaldehyde oxidase activity

4-hydroxyacetophenone monooxygenase activity

4-hydroxybenzoate 1-hydroxylase activity

4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity

4-hydroxybenzoate 3-monooxygenase activity

4-hydroxyphenylacetaldehyde oxime monooxygenase activity

4-hydroxyphenylacetate 1-monooxygenase activity

4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity

4-hydroxypyridine-3-hydroxylase activity

4-hydroxyquinoline 3-monooxygenase activity

4-nitrophenol 2-monooxygenase activity

4-nitrophenol 4-monooxygenase activity

5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity

5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity

6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity

6-hydroxynicotinate 3-monooxygenase activity

6-oxocineole dehydrogenase activity

7-deoxyloganin 7-hydroxylase activity

7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity

9beta-pimara-7,15-diene oxidase activity

abieta-7,13-dien-18-ol hydroxylase activity

abieta-7,13-diene hydroxylase activity

albendazole monooxygenase activity

alkene monooxygenase activity

alpha-pinene monooxygenase [NADH] activity

anhydrotetracycline monooxygenase activity

antheraxanthin epoxidase activity

anthranilate 3-monooxygenase (deaminating) activity

anthraniloyl-CoA monooxygenase activity

benzoate 4-monooxygenase activity

benzoyl-CoA 3-monooxygenase activity

bisphenol A hydroxylase A activity

branched-chain dodecylbenzene sulfonate monooxygenase activity

C-4 methylsterol oxidase activity +

calcidiol 1-monooxygenase activity

carbon disulfide oxygenase activity

chlorophenol 4-monooxygenase activity

cholest-4-en-3-one 26-monooxygenase activity

cholestanetriol 26-monooxygenase activity

cholesterol 24-hydroxylase activity

cholesterol 7-alpha-monooxygenase activity

cyclohexanone monooxygenase activity

cyclopentanone monooxygenase activity

deoxysarpagine hydroxylase activity

dibenzothiophene monooxygenase activity

dihydrochelirubine 12-monooxygenase activity

dihydrosanguinarine 10-monooxygenase activity

dimethyl sulfide monooxygenase activity

ent-7-alpha-hydroxykaurenoate oxidase activity

ent-cassa-12,15-diene 11-hydroxylase activity

ent-isokaurene C2-hydroxylase activity

ent-kaur-16-en-19-al oxidase activity

ent-kaur-16-en-19-ol oxidase activity

ent-kaurene oxidase activity

ent-kaurenoate oxidase activity

flavonoid 3',5'-hydroxylase activity

flavonoid 3'-monooxygenase activity

gibberellin 12-aldehyde oxidase activity

glyceollin synthase activity

hydroxyphenylacetonitrile 2-monooxygenase activity

imidazoleacetate 4-monooxygenase activity

indole-2-monooxygenase activity

indolin-2-one monooxygenase activity

isobutylamine N-hydroxylase activity

isoflavone 2'-hydroxylase activity

isoflavone 3'-hydroxylase activity

ketosteroid monooxygenase activity

kynurenine 3-monooxygenase activity

L-lysine 6-monooxygenase (NADPH) activity

L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)

L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

leukotriene-B4 20-monooxygenase activity

leukotriene-E4 20-monooxygenase activity

licodione synthase activity

limonene monooxygenase activity +

lithocholate 6beta-hydroxylase activity

magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity

melilotate 3-monooxygenase activity

methane monooxygenase activity

methanesulfonate monooxygenase activity

methyltetrahydroprotoberberine 14-monooxygenase activity

N,N-dimethylaniline monooxygenase activity

N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)

N-methylcoclaurine 3'-monooxygenase activity

nitric-oxide synthase activity [GO:0004517] (3 genes, 6 annotations)

orcinol 2-monooxygenase activity

pentachlorophenol monooxygenase activity

phenanthrene 1,2-monooxygenase activity

phenanthrene 3,4-monooxygenase activity

phenanthrene 9,10-monooxygenase activity

phenol 2-monooxygenase activity

phenylacetate hydroxylase activity

phenylacetone monooxygenase activity

phenylacetyl-CoA 1,2-epoxidase activity

phosphatidylcholine 12-monooxygenase activity

precorrin-3B synthase activity

protopine 6-monooxygenase activity

questin monooxygenase activity

quinine 3-monooxygenase activity

salicylate 1-monooxygenase activity

salicylate 5-hydroxylase activity

senecionine N-oxygenase activity

squalene monooxygenase activity

sterol 14-demethylase activity

styrene monooxygenase activity

tabersonine 16-hydroxylase activity

taurochenodeoxycholate 6alpha-hydroxylase activity

taxane 10-beta-hydroxylase activity

taxane 13-alpha-hydroxylase activity

taxifolin 8-monooxygenase activity

taxoid 14-beta-hydroxylase activity

taxoid 7beta-hydroxylase activity

tetrahydrofuran hydroxylase activity

tocopherol omega-hydroxylase activity +

tocotrienol omega-hydroxylase activity

toluene 2-monooxygenase activity

toluene 3-monooxygenase activity

toluene 4-monooxygenase activity

toluene-4-sulfonate monooxygenase activity

toluene-sulfonate methyl-monooxygenase activity

trans-cinnamate 2-monooxygenase activity

trans-cinnamate 4-monooxygenase activity

tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity +

tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity +

trimethylamine monooxygenase activity

tyrosine N-monooxygenase activity

vanillate monooxygenase activity

vinorine hydroxylase activity

xylene monooxygenase activity

zeaxanthin epoxidase [overall] activity

zeaxanthin epoxidase activity