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Gene Ontology Browser
Term Detail
GO term:monooxygenase activity
Synonym: hydroxylase activity
GO id:GO:0004497
Definition:Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-aoxidoreductase activity
                                is-a1,1,1-trichloroethane reductive dehalogenase activity
                                is-a1,1,2-trichloroethene reductive dehalogenase activity
                                is-a1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity
                                is-a1,1-dichloroethane reductive dehalogenase activity
                                is-a1,2-dichloroethene reductive dehalogenase activity
                                is-a2,4-dichloroaniline reductive dehalogenase activity
                                is-a2,4-dichlorophenoxyacetate dehalogenase activity
                                is-a2,5-dichlorohydroquinone reductive dehalogenase activity
                                is-a2-chloro-N-isopropylacetanilide reductive dehalogenase activity
                                is-a2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity
                                is-a2-octaprenylphenol hydroxylase activity
                                is-a2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity
                                is-a3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity
                                is-a3,3',5-tribromobisphenol A reductive dehalogenase activity
                                is-a3,3'-dibromobisphenol A reductive dehalogenase activity
                                is-a3,8-divinyl protochlorophyllide a 8-vinyl reductase activity
                                is-a3-monobromobisphenol A reductive dehalogenase activity
                                is-a[formate-C-acetyltransferase]-activating enzyme activity
                                is-aalpha-ketoacid dehydrogenase activity
                                is-aarsenate reductase activity +
                                is-achlorate reductase activity
                                is-achromate reductase activity
                                is-acrotonyl-CoA reductase activity
                                is-adelta1-piperideine-6-carboxylate dehydrogenase activity
                                is-adihydronicotinamide riboside quinone reductase activity
                                is-adihydropterin oxidase activity
                                is-adimethylarsinate reductase activity
                                is-adioxygenase activity +
                                is-aepoxyqueuosine reductase activity
                                is-afatty acid alpha-hydroxylase activity
                                is-ageranylgeranyl reductase activity
                                is-aheme-copper terminal oxidase activity +
                                is-ahydroxymethylbutenyl pyrophosphate reductase activity
                                is-amalolactic enzyme activity
                                is-amonooxygenase activity [GO:0004497] (150 genes, 638 annotations)
                                        is-a2-hydroxyisobutyrate 3-monooxygenase activity
                                        is-a2-hydroxypyridine 5-monooxygenase activity
                                        is-a20-aldehyde-leukotriene B4 20-monooxygenase activity
                                        is-a25-hydroxycholecalciferol-24-hydroxylase activity
                                        is-a3-hydroxybenzoate 2-monooxygenase activity
                                        is-a4-chlorophenoxyacetate monooxygenase activity
                                        is-a4-ketotorulene 3-hydroxylase activity
                                        is-a4-methoxybenzoate monooxygenase (O-demethylating) activity
                                        is-a4-nitrocatechol 4-monooxygenase activity
                                        is-aadonirubin 3-hydroxylase activity
                                        is-aalpha-pinene monooxygenase activity
                                        is-aammonia monooxygenase activity
                                        is-aandrost-4-ene-3,17-dione monooxygenase activity
                                        is-aarachidonic acid monooxygenase activity +
                                        is-abeta-carotene 3-hydroxylase activity
                                        is-abeta-cryptoxanthin hydroxylase activity
                                        is-acanthaxanthin 3-hydroxylase activity
                                        is-acarotene beta-ring hydroxylase activity
                                        is-acarotene epsilon hydroxylase activity +
                                        is-acoumarin 7-hydroxylase activity
                                        is-adeoxyhypusine monooxygenase activity
                                        is-adibenzothiophene-5,5-dioxide monooxygenase activity
                                        is-aechinenone 3-hydroxylase activity
                                        is-aestradiol 6-beta-monooxygenase activity
                                        is-afatty acid in-chain hydroxylase activity
                                        is-aferulate 5-hydroxylase activity
                                        is-ajasmonoyl-isoleucine-12-hydroxylase activity
                                        is-alinalool 8-monooxygenase activity
                                        is-alinoleic acid epoxygenase activity
                                        is-aluciferin monooxygenase activity +
                                        is-amethyl tertiary butyl ether 3-monooxygenase activity
                                        is-anaphthalene hydroxylase activity
                                        is-anitrilotriacetate monooxygenase activity
                                        is-aornithine N5-monooxygenase activity
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen +
                                        is-aoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +
                                        is-ap-coumarate 3-hydroxylase activity
                                        is-aphylloquinone monooxygenase (2,3-epoxidizing) activity
                                        is-aprogesterone 11-alpha-monooxygenase activity
                                        is-aprogesterone monooxygenase activity
                                        is-aretinoic acid 4-hydroxylase activity
                                        is-asteroid 9-alpha-monooxygenase activity
                                        is-asteroid hydroxylase activity +
                                        is-atert-butanol 2-monooxygenase activity
                                        is-athalianol hydroxylase activity
                                        is-athiophene-2-carbonyl-CoA monooxygenase activity
                                is-aN-ethylmaleimide reductase activity
                                is-aNADPH-adrenodoxin reductase activity
                                is-aNADPH:sulfur oxidoreductase activity
                                is-aortho-trichlorophenol reductive dehalogenase activity
                                is-aoxidative DNA demethylase activity
                                is-aoxidative RNA demethylase activity
                                is-aoxidoreductase activity, acting on a heme group of donors +
                                is-aoxidoreductase activity, acting on a sulfur group of donors +
                                is-aoxidoreductase activity, acting on CH or CH2 groups +
                                is-aoxidoreductase activity, acting on CH-OH group of donors +
                                is-aoxidoreductase activity, acting on diphenols and related substances as donors +
                                is-aoxidoreductase activity, acting on halogen in donors +
                                is-aoxidoreductase activity, acting on hydrogen as donor +
                                is-aoxidoreductase activity, acting on iron-sulfur proteins as donors +
                                is-aoxidoreductase activity, acting on NAD(P)H +
                                is-aoxidoreductase activity, acting on other nitrogenous compounds as donors +
                                is-aoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen +
                                is-aoxidoreductase activity, acting on peroxide as acceptor +
                                is-aoxidoreductase activity, acting on phosphorus or arsenic in donors +
                                is-aoxidoreductase activity, acting on reduced flavodoxin as donor +
                                is-aoxidoreductase activity, acting on single donors with incorporation of molecular oxygen +
                                is-aoxidoreductase activity, acting on superoxide radicals as acceptor +
                                is-aoxidoreductase activity, acting on the aldehyde or oxo group of donors +
                                is-aoxidoreductase activity, acting on the CH-CH group of donors +
                                is-aoxidoreductase activity, acting on the CH-NH group of donors +
                                is-aoxidoreductase activity, acting on the CH-NH2 group of donors +
                                is-aoxidoreductase activity, acting on X-H and Y-H to form an X-Y bond +
                                is-aoxidoreductase activity, oxidizing metal ions +
                                is-aoxygen evolving activity
                                is-aperchlorate reductase activity
                                is-aphthalate dioxygenase reductase activity
                                is-apyrogallol hydroxytransferase activity
                                is-areduced coenzyme F420 dehydrogenase activity
                                is-areduced coenzyme F420 oxidase activity
                                is-areduced coenzyme F420:quinone oxidoreductase activity
                                is-aselenate reductase activity
                                is-asphingosine hydroxylase activity
                                is-asteroid dehydrogenase activity +
                                is-asulfur oxygenase reductase activity
                                is-asulfur reductase activity
                                is-atetrachloroethene reductive dehalogenase activity
                                is-atetrahydrothiophene 1-oxide reductase activity
                                is-athyroxine 5'-deiodinase activity
                                is-athyroxine 5-deiodinase activity
                                is-atrimethylarsine oxidase activity
                                is-atRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity
                                is-atyramine-beta hydroxylase activity
                                is-auracil oxygenase activity
                                is-avinyl chloride reductive dehalogenase activity
                                is-aviolaxanthin de-epoxidase activity
                                is-avitamin D 24-hydroxylase activity +
                                is-avitamin D 25-hydroxylase activity +


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory